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Acquired hemophilia B

MedGen UID:
98305
•Concept ID:
C0398609
•
Disease or Syndrome
Synonyms: Acquired F9 deficiency; Acquired factor IX deficiency; Acquired Factor IX Deficiency; Acquired factor IX deficiency disease; acquired hemophilia B; AHB; Hemophilia B, acquired
SNOMED CT: Acquired factor IX deficiency (12153008); Acquired factor IX deficiency disease (12153008); Hemophilia B, acquired (12153008)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0035736
Orphanet: ORPHA599485

Definition

An acquired coagulation disorder characterized by the partial or complete absence of factor IX activity in the blood. [from NCI]

Professional guidelines

PubMed

Practices and challenges for hemophilia management under resource constraints in Thailand.
Moonla C, Sosothikul D, Pongtanakul B, Suwanawiboon B, Traivaree C, Natesirinilkul R, Sirachainan N, Angchaisuksiri P
Orphanet J Rare Dis 2023 May 10;18(1):110. doi: 10.1186/s13023-023-02718-1. PMID: 37161533Free PMC Article
Paradigm shift for the treatment of hereditary haemophilia: Towards precision medicine.
Spadarella G, Di Minno A, Milan G, Franco N, Polimeno M, Castaldo F, Di Minno G
Blood Rev 2020 Jan;39:100618. Epub 2019 Oct 15 doi: 10.1016/j.blre.2019.100618. PMID: 31676141
Management of haemophilia.
Jones P
Arch Dis Child 1984 Nov;59(11):1010-2. doi: 10.1136/adc.59.11.1010. PMID: 6439126Free PMC Article

Recent clinical studies

Clinical prediction guides

Influence of factor VIIa and phospholipids on coagulation in "acquired" hemophilia.
Butenas S, Brummel KE, Paradis SG, Mann KG
Arterioscler Thromb Vasc Biol 2003 Jan 1;23(1):123-9. doi: 10.1161/01.atv.0000042081.57854.a2. PMID: 12524235

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