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Tonsillopharyngitis

MedGen UID:
922968
•Concept ID:
C0749591
•
Disease or Syndrome

Definition

Inflammation of the palatine tonsils and the posterior pharynx (throat). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTonsillopharyngitis

Professional guidelines

PubMed

Antimicrobial treatment of ENT infections.
Cohen R, Madhi F, Thollot F, Hau I, Vie le Sage F, Lemaître C, Magendie C, Werner A, Gelbert N, Cohen JF, Couloigner V
Infect Dis Now 2023 Nov;53(8S):104785. Epub 2023 Sep 18 doi: 10.1016/j.idnow.2023.104785. PMID: 37730165
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689

Recent clinical studies

Etiology

Antimicrobial treatment of ENT infections.
Cohen R, Madhi F, Thollot F, Hau I, Vie le Sage F, Lemaître C, Magendie C, Werner A, Gelbert N, Cohen JF, Couloigner V
Infect Dis Now 2023 Nov;53(8S):104785. Epub 2023 Sep 18 doi: 10.1016/j.idnow.2023.104785. PMID: 37730165
Fusobacterium necrophorum oral infections - A need for guidance.
Centor RM, Atkinson TP, Xiao L
Anaerobe 2022 Jun;75:102532. Epub 2022 Feb 2 doi: 10.1016/j.anaerobe.2022.102532. PMID: 35122953
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689
Tonsillopharyngitis 1994.
Denny FW Jr
Pediatr Rev 1994 May;15(5):185-91. doi: 10.1542/pir.15-5-185. PMID: 8036194

Diagnosis

Antimicrobial treatment of ENT infections.
Cohen R, Madhi F, Thollot F, Hau I, Vie le Sage F, Lemaître C, Magendie C, Werner A, Gelbert N, Cohen JF, Couloigner V
Infect Dis Now 2023 Nov;53(8S):104785. Epub 2023 Sep 18 doi: 10.1016/j.idnow.2023.104785. PMID: 37730165
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Lemierre's syndrome: A forgotten and re-emerging infection.
Lee WS, Jean SS, Chen FL, Hsieh SM, Hsueh PR
J Microbiol Immunol Infect 2020 Aug;53(4):513-517. Epub 2020 Apr 4 doi: 10.1016/j.jmii.2020.03.027. PMID: 32303484
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689
Tonsillopharyngitis 1994.
Denny FW Jr
Pediatr Rev 1994 May;15(5):185-91. doi: 10.1542/pir.15-5-185. PMID: 8036194

Therapy

Antimicrobial treatment of ENT infections.
Cohen R, Madhi F, Thollot F, Hau I, Vie le Sage F, Lemaître C, Magendie C, Werner A, Gelbert N, Cohen JF, Couloigner V
Infect Dis Now 2023 Nov;53(8S):104785. Epub 2023 Sep 18 doi: 10.1016/j.idnow.2023.104785. PMID: 37730165
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Lemierre's syndrome: A forgotten and re-emerging infection.
Lee WS, Jean SS, Chen FL, Hsieh SM, Hsueh PR
J Microbiol Immunol Infect 2020 Aug;53(4):513-517. Epub 2020 Apr 4 doi: 10.1016/j.jmii.2020.03.027. PMID: 32303484
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689
Tonsillopharyngitis 1994.
Denny FW Jr
Pediatr Rev 1994 May;15(5):185-91. doi: 10.1542/pir.15-5-185. PMID: 8036194

Prognosis

Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Defining the optimum treatment regimen for azithromycin in acute tonsillopharyngitis.
Cohen R
Pediatr Infect Dis J 2004 Feb;23(2 Suppl):S129-34. doi: 10.1097/01.inf.0000112527.33870.0d. PMID: 14770076
Short-Course antimicrobial therapy for upper respiratory tract infections.
Guay DR
Clin Ther 2000 Jun;22(6):673-84. doi: 10.1016/S0149-2918(00)90003-1. PMID: 10929916
Tonsillopharyngitis: evaluation of short-term treatment with cefuroxime axetil versus standard 10-day penicillin V therapy.
Gehanno P, Chichie D
Br J Clin Pract 1995 Jan-Feb;49(1):28-32. PMID: 7742180
Tonsillopharyngitis 1994.
Denny FW Jr
Pediatr Rev 1994 May;15(5):185-91. doi: 10.1542/pir.15-5-185. PMID: 8036194

Clinical prediction guides

Respiratory Diagnoses Year-Round: Unraveling the Multifaceted Pediatric Infection Cycles.
Walkowiak MP, Walkowiak J, Walkowiak D
Influenza Other Respir Viruses 2024 Nov;18(11):e70037. doi: 10.1111/irv.70037. PMID: 39497019Free PMC Article
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
A highly-sensitive rapid test for the diagnosis of streptococcal pharyngitis: BD veritor ™ system.
Bulut ME, Kına N, Büyükyanbolu E, Özer VY, Aktaş E, Bayraktar B
Int J Pediatr Otorhinolaryngol 2020 Jun;133:109980. Epub 2020 Mar 4 doi: 10.1016/j.ijporl.2020.109980. PMID: 32197187
Increase in fluoroquinolone non-susceptibility among clinical Streptococcus pyogenes in Belgium during 2007-10.
Van Heirstraeten L, Leten G, Lammens C, Goossens H, Malhotra-Kumar S
J Antimicrob Chemother 2012 Nov;67(11):2602-5. Epub 2012 Jul 19 doi: 10.1093/jac/dks281. PMID: 22815354
Relief of symptoms in patients with group A beta-hemolytic streptococcus tonsillopharyngitis: comparison between telithromycin and penicillin V.
Norrby SR, Chang J, Stewart JA, Brumpt I, Conway DP
Scand J Infect Dis 2003;35(4):223-5. doi: 10.1080/0036554021000027021. PMID: 12839147

Recent systematic reviews

Different antibiotic treatments for group A streptococcal pharyngitis.
Hedin K, Thorning S, van Driel ML
Cochrane Database Syst Rev 2023 Nov 15;11(11):CD004406. doi: 10.1002/14651858.CD004406.pub6. PMID: 37965935Free PMC Article
Complementary and alternative medicine in the (symptomatic) treatment of acute tonsillitis in children: A systematic review.
Büttner R, Schwermer M, Ostermann T, Längler A, Zuzak T
Complement Ther Med 2023 May;73:102940. Epub 2023 Mar 1 doi: 10.1016/j.ctim.2023.102940. PMID: 36868289
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Thorning S, Christiaens T
Cochrane Database Syst Rev 2021 Mar 17;3(3):CD004406. doi: 10.1002/14651858.CD004406.pub5. PMID: 33728634Free PMC Article
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Keber N, Habraken H, Christiaens T
Cochrane Database Syst Rev 2013 Apr 30;(4):CD004406. doi: 10.1002/14651858.CD004406.pub3. PMID: 23633318
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Keber N, Habraken H, Christiaens T
Cochrane Database Syst Rev 2010 Oct 6;(10):CD004406. doi: 10.1002/14651858.CD004406.pub2. PMID: 20927734

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