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Intestinal type adenocarcinoma

MedGen UID:
87206
•Concept ID:
C0334279
•
Neoplastic Process
Synonyms: Adenocarcinoma - intestinal type; Adenocarcinoma, intestinal type; Adenocarcinoma, Intestinal Type; Carcinoma - intestinal type; Carcinoma, intestinal type; intestinal type adenocarcinoma; Intestinal Type Carcinoma; intestinal type carcinoma; Intestinal-Type Adenocarcinoma; intestinal-type adenocarcinoma
SNOMED CT: Carcinoma - intestinal type (25190001); Adenocarcinoma - intestinal type (25190001); Adenocarcinoma, intestinal type (25190001); Carcinoma, intestinal type (25190001)
 
Monarch Initiative: MONDO:0006254

Definition

An adenocarcinoma arising from epithelium which has undergone intestinal metaplasia. Representative examples include gastric, gallbladder, and ampulla of Vater intestinal type adenocarcinomas. [from NCI]

Professional guidelines

PubMed

Molecular Biomarkers in Sinonasal Cancers: New Frontiers in Diagnosis and Treatment.
Turri-Zanoni M, Gravante G, Castelnuovo P
Curr Oncol Rep 2022 Jan;24(1):55-67. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01154-3. PMID: 35059992Free PMC Article
Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and Differential Diagnosis.
Leivo I
Head Neck Pathol 2017 Sep;11(3):295-300. Epub 2017 Mar 20 doi: 10.1007/s12105-017-0800-7. PMID: 28321774Free PMC Article
Intestinal-type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment.
Hoeben A, van de Winkel L, Hoebers F, Kross K, Driessen C, Slootweg P, Tjan-Heijnen VC, van Herpen C
Head Neck 2016 Oct;38(10):1564-70. Epub 2016 May 25 doi: 10.1002/hed.24416. PMID: 27224655

Recent clinical studies

Etiology

Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma.
Codina-Martínez H, Lorenzo-Guerra SL, Cabal VN, García-Marín R, Suárez-Fernández L, Vivanco B, Sánchez-Fernández P, López F, Llorente JL, Hermsen MA
Int J Mol Sci 2023 Oct 12;24(20) doi: 10.3390/ijms242015110. PMID: 37894790Free PMC Article
Sinonasal low-grade non-intestinal-type adenocarcinoma: A retrospective analysis and literature review.
Yue C, Piao Y, Bai Y, Liu H, Zhang L
Ann Diagn Pathol 2021 Jun;52:151709. Epub 2021 Jan 29 doi: 10.1016/j.anndiagpath.2021.151709. PMID: 33550111
Intestinal-type adenocarcinoma of the sinonasal tract: an update.
Rampinelli V, Ferrari M, Nicolai P
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):115-121. doi: 10.1097/MOO.0000000000000445. PMID: 29389737
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974
Intestinal-Type Adenocarcinoma Arising in a Mature Cystic Teratoma of the Ovary.
Clark ME, Will MD
Int J Gynecol Pathol 2016 Jul;35(4):352-6. doi: 10.1097/PGP.0000000000000258. PMID: 26937866

Diagnosis

Sinonasal Adenocarcinomas: An Update.
Arcovito G, Franchi A
Surg Pathol Clin 2024 Dec;17(4):653-666. Epub 2024 Aug 17 doi: 10.1016/j.path.2024.07.005. PMID: 39489555
Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and Differential Diagnosis.
Leivo I
Head Neck Pathol 2017 Sep;11(3):295-300. Epub 2017 Mar 20 doi: 10.1007/s12105-017-0800-7. PMID: 28321774Free PMC Article
Intestinal-type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment.
Hoeben A, van de Winkel L, Hoebers F, Kross K, Driessen C, Slootweg P, Tjan-Heijnen VC, van Herpen C
Head Neck 2016 Oct;38(10):1564-70. Epub 2016 May 25 doi: 10.1002/hed.24416. PMID: 27224655
Sinonasal Adenocarcinoma: Update on Classification, Immunophenotype and Molecular Features.
Leivo I
Head Neck Pathol 2016 Mar;10(1):68-74. Epub 2016 Feb 1 doi: 10.1007/s12105-016-0694-9. PMID: 26830399Free PMC Article
Pulmonary intestinal-type adenocarcinoma.
Maeda R, Isowa N, Onuma H, Miura H
Interact Cardiovasc Thorac Surg 2008 Apr;7(2):349-51. Epub 2008 Jan 9 doi: 10.1510/icvts.2007.168716. PMID: 18184677

Therapy

Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma.
Codina-Martínez H, Lorenzo-Guerra SL, Cabal VN, García-Marín R, Suárez-Fernández L, Vivanco B, Sánchez-Fernández P, López F, Llorente JL, Hermsen MA
Int J Mol Sci 2023 Oct 12;24(20) doi: 10.3390/ijms242015110. PMID: 37894790Free PMC Article
5-fluorouracil with oxaliplatin and/or irinotecan for advanced sinonasal intestinal-type adenocarcinoma (ITAC).
Sarradin V, Betrian S, Chaltiel L, Brac De La Perriere C, Delord JP
Bull Cancer 2023 Feb;110(2):168-173. Epub 2022 Nov 10 doi: 10.1016/j.bulcan.2022.10.004. PMID: 36372589
The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Skalova A, Sar A, Laco J, Metelkova A, Miesbauerova M, Steiner P, Švajdler M, Michal M
Appl Immunohistochem Mol Morphol 2018 Feb;26(2):140-146. doi: 10.1097/PAI.0000000000000388. PMID: 27258560
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974
The role of systemic therapy in the management of sinonasal cancer: A critical review.
Bossi P, Saba NF, Vermorken JB, Strojan P, Pala L, de Bree R, Rodrigo JP, Lopez F, Hanna EY, Haigentz M, Takes RP, Slootweg PJ, Silver CE, Rinaldo A, Ferlito A
Cancer Treat Rev 2015 Dec;41(10):836-43. Epub 2015 Jul 31 doi: 10.1016/j.ctrv.2015.07.004. PMID: 26255226

Prognosis

Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma.
Codina-Martínez H, Lorenzo-Guerra SL, Cabal VN, García-Marín R, Suárez-Fernández L, Vivanco B, Sánchez-Fernández P, López F, Llorente JL, Hermsen MA
Int J Mol Sci 2023 Oct 12;24(20) doi: 10.3390/ijms242015110. PMID: 37894790Free PMC Article
HER2 status in sinonasal intestinal-type adenocarcinoma.
Maffeis V, Cappellesso R, Zanon A, Cazzador D, Emanuelli E, Martini A, Fassina A
Pathol Res Pract 2019 Jun;215(6):152432. Epub 2019 Apr 28 doi: 10.1016/j.prp.2019.04.024. PMID: 31047725
Intestinal-type adenocarcinoma of the sinonasal tract: an update.
Rampinelli V, Ferrari M, Nicolai P
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):115-121. doi: 10.1097/MOO.0000000000000445. PMID: 29389737
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974
Intestinal-type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment.
Hoeben A, van de Winkel L, Hoebers F, Kross K, Driessen C, Slootweg P, Tjan-Heijnen VC, van Herpen C
Head Neck 2016 Oct;38(10):1564-70. Epub 2016 May 25 doi: 10.1002/hed.24416. PMID: 27224655

Clinical prediction guides

Outcomes of endoscopic submucosal dissection for intestinal-type adenocarcinoma with anastomosing glands of the stomach.
Kim TS, Kim B, Min BH, Min YW, Lee H, Lee JH, Rhee PL, Kim JJ, Kushima R, Kim KM
J Gastroenterol Hepatol 2020 Jan;35(1):50-55. Epub 2019 Jul 29 doi: 10.1111/jgh.14756. PMID: 31242325
HER2 status in sinonasal intestinal-type adenocarcinoma.
Maffeis V, Cappellesso R, Zanon A, Cazzador D, Emanuelli E, Martini A, Fassina A
Pathol Res Pract 2019 Jun;215(6):152432. Epub 2019 Apr 28 doi: 10.1016/j.prp.2019.04.024. PMID: 31047725
Intestinal-type adenocarcinoma of the vagina: clinico-pathologic features of a common tumor with a rare localization.
Broggi G, Piombino E, Magro G, Vecchio GM
Pathologica 2018 Sep;110(2):92-95. PMID: 30546144
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974
Pulmonary intestinal-type adenocarcinoma does not show enteric differentiation by immunohistochemical study.
Yousem SA
Mod Pathol 2005 Jun;18(6):816-21. doi: 10.1038/modpathol.3800358. PMID: 15605076

Recent systematic reviews

Tumors of the Nose and Paranasal Sinuses: Promoting Factors and Molecular Mechanisms-A Systematic Review.
Lucidi D, Cantaffa C, Miglio M, Spina F, Alicandri Ciufelli M, Marchioni A, Marchioni D
Int J Mol Sci 2023 Jan 31;24(3) doi: 10.3390/ijms24032670. PMID: 36768990Free PMC Article
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974

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