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Abnormality of vitamin B12 metabolism

MedGen UID:
867295
•Concept ID:
C4021658
•
Finding
Synonym: Abnormality of the vitamin B12 metabolism
 
HPO: HP:0004341

Professional guidelines

PubMed

Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048
Recognition and Differential Diagnosis of Psychosis in Primary Care.
Griswold KS, Del Regno PA, Berger RC
Am Fam Physician 2015 Jun 15;91(12):856-63. PMID: 26131945
Cobalamin C defect: natural history, pathophysiology, and treatment.
Martinelli D, Deodato F, Dionisi-Vici C
J Inherit Metab Dis 2011 Feb;34(1):127-35. Epub 2010 Jul 15 doi: 10.1007/s10545-010-9161-z. PMID: 20632110

Recent clinical studies

Etiology

Folic acid versus 5- methyl tetrahydrofolate supplementation in pregnancy.
Ferrazzi E, Tiso G, Di Martino D
Eur J Obstet Gynecol Reprod Biol 2020 Oct;253:312-319. Epub 2020 Jun 13 doi: 10.1016/j.ejogrb.2020.06.012. PMID: 32868164
Folic acid and primary prevention of neural tube defects: A review.
van Gool JD, Hirche H, Lax H, De Schaepdrijver L
Reprod Toxicol 2018 Sep;80:73-84. Epub 2018 May 16 doi: 10.1016/j.reprotox.2018.05.004. PMID: 29777755
Vitamin B(12) deficiency.
Green R, Allen LH, Bjørke-Monsen AL, Brito A, Guéant JL, Miller JW, Molloy AM, Nexo E, Stabler S, Toh BH, Ueland PM, Yajnik C
Nat Rev Dis Primers 2017 Jun 29;3:17040. doi: 10.1038/nrdp.2017.40. PMID: 28660890
Vitamin B12 in health and disease.
O'Leary F, Samman S
Nutrients 2010 Mar;2(3):299-316. Epub 2010 Mar 5 doi: 10.3390/nu2030299. PMID: 22254022Free PMC Article
Evaluation of macrocytosis.
Kaferle J, Strzoda CE
Am Fam Physician 2009 Feb 1;79(3):203-8. PMID: 19202968

Diagnosis

Vitamin B12 deficiency: case report and review of literature.
Hasbaoui BE, Mebrouk N, Saghir S, Yajouri AE, Abilkassem R, Agadr A
Pan Afr Med J 2021;38:237. Epub 2021 Mar 4 doi: 10.11604/pamj.2021.38.237.20967. PMID: 34046142Free PMC Article
Vitamin B(12) deficiency.
Green R, Allen LH, Bjørke-Monsen AL, Brito A, Guéant JL, Miller JW, Molloy AM, Nexo E, Stabler S, Toh BH, Ueland PM, Yajnik C
Nat Rev Dis Primers 2017 Jun 29;3:17040. doi: 10.1038/nrdp.2017.40. PMID: 28660890
Vitamin B12 deficiency - A 21st century perspective .
Shipton MJ, Thachil J
Clin Med (Lond) 2015 Apr;15(2):145-50. doi: 10.7861/clinmedicine.15-2-145. PMID: 25824066Free PMC Article
The pathophysiology of elevated vitamin B12 in clinical practice.
Andrès E, Serraj K, Zhu J, Vermorken AJ
QJM 2013 Jun;106(6):505-15. Epub 2013 Feb 27 doi: 10.1093/qjmed/hct051. PMID: 23447660
Evaluation of macrocytosis.
Kaferle J, Strzoda CE
Am Fam Physician 2009 Feb 1;79(3):203-8. PMID: 19202968

Therapy

Vitamin B12 deficiency: case report and review of literature.
Hasbaoui BE, Mebrouk N, Saghir S, Yajouri AE, Abilkassem R, Agadr A
Pan Afr Med J 2021;38:237. Epub 2021 Mar 4 doi: 10.11604/pamj.2021.38.237.20967. PMID: 34046142Free PMC Article
AGA Clinical Practice Update on Small Intestinal Bacterial Overgrowth: Expert Review.
Quigley EMM, Murray JA, Pimentel M
Gastroenterology 2020 Oct;159(4):1526-1532. Epub 2020 Jul 15 doi: 10.1053/j.gastro.2020.06.090. PMID: 32679220
Folic acid and primary prevention of neural tube defects: A review.
van Gool JD, Hirche H, Lax H, De Schaepdrijver L
Reprod Toxicol 2018 Sep;80:73-84. Epub 2018 May 16 doi: 10.1016/j.reprotox.2018.05.004. PMID: 29777755
Vitamin B12 deficiency - A 21st century perspective .
Shipton MJ, Thachil J
Clin Med (Lond) 2015 Apr;15(2):145-50. doi: 10.7861/clinmedicine.15-2-145. PMID: 25824066Free PMC Article
Evaluation of macrocytosis.
Kaferle J, Strzoda CE
Am Fam Physician 2009 Feb 1;79(3):203-8. PMID: 19202968

Prognosis

Vitamin B12 deficiency: case report and review of literature.
Hasbaoui BE, Mebrouk N, Saghir S, Yajouri AE, Abilkassem R, Agadr A
Pan Afr Med J 2021;38:237. Epub 2021 Mar 4 doi: 10.11604/pamj.2021.38.237.20967. PMID: 34046142Free PMC Article
Recognition and Differential Diagnosis of Psychosis in Primary Care.
Griswold KS, Del Regno PA, Berger RC
Am Fam Physician 2015 Jun 15;91(12):856-63. PMID: 26131945
The pathophysiology of elevated vitamin B12 in clinical practice.
Andrès E, Serraj K, Zhu J, Vermorken AJ
QJM 2013 Jun;106(6):505-15. Epub 2013 Feb 27 doi: 10.1093/qjmed/hct051. PMID: 23447660
Cobalamin C defect: natural history, pathophysiology, and treatment.
Martinelli D, Deodato F, Dionisi-Vici C
J Inherit Metab Dis 2011 Feb;34(1):127-35. Epub 2010 Jul 15 doi: 10.1007/s10545-010-9161-z. PMID: 20632110
Evaluation of macrocytosis.
Kaferle J, Strzoda CE
Am Fam Physician 2009 Feb 1;79(3):203-8. PMID: 19202968

Clinical prediction guides

Vitamin B12 deficiency and metabolism-mediated thrombotic microangiopathy (MM-TMA).
Sabry W, Elemary M, Burnouf T, Seghatchian J, Goubran H
Transfus Apher Sci 2020 Feb;59(1):102717. Epub 2019 Dec 31 doi: 10.1016/j.transci.2019.102717. PMID: 31902683
Pearls: myelopathy.
Kumar N
Semin Neurol 2010 Feb;30(1):38-43. Epub 2010 Feb 1 doi: 10.1055/s-0029-1244993. PMID: 20127580
Evaluation of macrocytosis.
Kaferle J, Strzoda CE
Am Fam Physician 2009 Feb 1;79(3):203-8. PMID: 19202968
Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment.
Solomon LR
Blood Rev 2007 May;21(3):113-30. Epub 2006 Jul 11 doi: 10.1016/j.blre.2006.05.001. PMID: 16814909
Physiology of folate and vitamin B12 in health and disease.
Stover PJ
Nutr Rev 2004 Jun;62(6 Pt 2):S3-12; discussion S13. doi: 10.1111/j.1753-4887.2004.tb00070.x. PMID: 15298442

Recent systematic reviews

Vitamin B12 deficiency in inflammatory bowel disease: prevalence, risk factors, evaluation, and management.
Battat R, Kopylov U, Szilagyi A, Saxena A, Rosenblatt DS, Warner M, Bessissow T, Seidman E, Bitton A
Inflamm Bowel Dis 2014 Jun;20(6):1120-8. doi: 10.1097/MIB.0000000000000024. PMID: 24739632
Micronutrient deficiencies after bariatric surgery.
Shankar P, Boylan M, Sriram K
Nutrition 2010 Nov-Dec;26(11-12):1031-7. Epub 2010 Apr 3 doi: 10.1016/j.nut.2009.12.003. PMID: 20363593
Oral cobalamin (vitamin B(12)) treatment. An update.
Andrès E, Dali-Youcef N, Vogel T, Serraj K, Zimmer J
Int J Lab Hematol 2009 Feb;31(1):1-8. Epub 2008 Nov 19 doi: 10.1111/j.1751-553X.2008.01115.x. PMID: 19032377
Vitamin B12 insufficiency and the risk of fetal neural tube defects.
Ray JG, Blom HJ
QJM 2003 Apr;96(4):289-95. doi: 10.1093/qjmed/hcg043. PMID: 12651973
Blood folic acid and vitamin B12 in relation to neural tube defects.
Wald NJ, Hackshaw AD, Stone R, Sourial NA
Br J Obstet Gynaecol 1996 Apr;103(4):319-24. doi: 10.1111/j.1471-0528.1996.tb09735.x. PMID: 8605127

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