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Ovarian Hilus Cell Tumor

MedGen UID:
83413
•Concept ID:
C0346179
•
Neoplastic Process
Synonyms: Hilar Cell Neoplasm; Hilar cell tumor; Hilar Cell Tumor of Ovary; Hilar Cell Tumor of the Ovary; Hilus Cell Neoplasm; Hilus cell tumor; Hilus Cell Tumor; Hilus cell tumor of ovary; Ovarian Hilar Cell Tumor
SNOMED CT: Hilus cell tumor (11506001); Hilar cell tumor (11506001); Hilus cell tumor of ovary (254868008)

Definition

A benign Leydig cell tumor which arises in the hilar area of the ovary. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Hilus Cell Tumor

Professional guidelines

PubMed

Ovarian pathology in risk-reducing salpingo-oophorectomies from women with BRCA mutations, emphasizing the differential diagnosis of occult primary and metastatic carcinoma.
Rabban JT, Barnes M, Chen LM, Powell CB, Crawford B, Zaloudek CJ
Am J Surg Pathol 2009 Aug;33(8):1125-36. doi: 10.1097/PAS.0b013e31819e986a. PMID: 19440148
Value of A103 (melan-A) immunostaining in the differential diagnosis of ovarian sex cord stromal tumours.
Stewart CJ, Nandini CL, Richmond JA
J Clin Pathol 2000 Mar;53(3):206-11. doi: 10.1136/jcp.53.3.206. PMID: 10823140Free PMC Article

Recent clinical studies

Diagnosis

Woman with virilizing congenital adrenal hyperplasia and Leydig cell tumor of the ovary.
Fernández-García Salazar R, Muñoz-Darias C, Haro-Mora JJ, Almaraz MC, Audí L, Martínez-Tudela J, Yahyaoui R, Esteva I
Gynecol Endocrinol 2014 Aug;30(8):549-52. Epub 2014 Apr 7 doi: 10.3109/09513590.2014.907260. PMID: 24702195
Histopathology and ultrastructure of ovarian hilus cell tumor: report of two cases.
Sohval AR, Churg J, Cobin RH, Katz N, Gabrilove JL
Gynecol Oncol 1979 Feb;7(1):79-101. doi: 10.1016/0090-8258(79)90084-2. PMID: 220151

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