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feeding intolerance

MedGen UID:
810928
•Concept ID:
C1820738
•
Finding
Synonym: Feeding intolerance

Definition

Inability to achieve a full feeding volume. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVfeeding intolerance

Professional guidelines

PubMed

Best evidence summary for prevention and management of enteral feeding intolerance in critically ill patients.
Peng F, Wang H, Li J, Ma M, Jiang X, Run H, Li Q, Leng J, Xiao L, Tang L
J Clin Nurs 2024 Mar;33(3):781-796. Epub 2023 Nov 22 doi: 10.1111/jocn.16934. PMID: 37994227
Glycerin laxatives for prevention or treatment of feeding intolerance in very low birth weight infants.
Anabrees J, Shah VS, AlOsaimi A, AlFaleh K
Cochrane Database Syst Rev 2015 Sep 30;2015(9):CD010464. doi: 10.1002/14651858.CD010464.pub2. PMID: 26421424Free PMC Article
Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems.
Reintam Blaser A, Malbrain ML, Starkopf J, Fruhwald S, Jakob SM, De Waele J, Braun JP, Poeze M, Spies C
Intensive Care Med 2012 Mar;38(3):384-94. Epub 2012 Feb 7 doi: 10.1007/s00134-011-2459-y. PMID: 22310869Free PMC Article

Recent clinical studies

Etiology

Best evidence summary for prevention and management of enteral feeding intolerance in critically ill patients.
Peng F, Wang H, Li J, Ma M, Jiang X, Run H, Li Q, Leng J, Xiao L, Tang L
J Clin Nurs 2024 Mar;33(3):781-796. Epub 2023 Nov 22 doi: 10.1111/jocn.16934. PMID: 37994227
The effect of oropharyngeal colostrum administration on the clinical outcomes of premature infants: A meta-analysis.
Fu ZY, Huang C, Lei L, Chen LC, Wei LJ, Zhou J, Tao M, Quan MT, Huang Y
Int J Nurs Stud 2023 Aug;144:104527. Epub 2023 May 19 doi: 10.1016/j.ijnurstu.2023.104527. PMID: 37295286
Effects of kangaroo mother care on feeding intolerance in preterm infants.
Çaka SY, Topal S, Yurttutan S, Aytemiz S, Çıkar Y, Sarı M
J Trop Pediatr 2023 Feb 6;69(2) doi: 10.1093/tropej/fmad015. PMID: 36897067Free PMC Article
Positive Effects of Kangaroo Mother Care on Long-Term Breastfeeding Rates, Growth, and Neurodevelopment in Preterm Infants.
Wang Y, Zhao T, Zhang Y, Li S, Cong X
Breastfeed Med 2021 Apr;16(4):282-291. Epub 2021 Feb 2 doi: 10.1089/bfm.2020.0358. PMID: 33533688
Necrotizing enterocolitis: It's not all in the gut.
Meister AL, Doheny KK, Travagli RA
Exp Biol Med (Maywood) 2020 Jan;245(2):85-95. Epub 2019 Dec 6 doi: 10.1177/1535370219891971. PMID: 31810384Free PMC Article

Diagnosis

Gastrointestinal function in critically ill patients.
Reintam Blaser A, Bachmann KF, Deane AM
Curr Opin Clin Nutr Metab Care 2023 Sep 1;26(5):463-469. Epub 2023 Jun 19 doi: 10.1097/MCO.0000000000000955. PMID: 37389469
Current insights in ICU nutrition: tailored nutrition.
Hermans AJH, Laarhuis BI, Kouw IWK, van Zanten ARH
Curr Opin Crit Care 2023 Apr 1;29(2):101-107. Epub 2023 Jan 27 doi: 10.1097/MCC.0000000000001016. PMID: 36762671Free PMC Article
Optimal Nutrition Parameters for Neonates and Infants with Congenital Heart Disease.
Luca AC, Miron IC, Mîndru DE, Curpăn AȘ, Stan RC, Țarcă E, Luca FA, Pădureț AI
Nutrients 2022 Apr 17;14(8) doi: 10.3390/nu14081671. PMID: 35458233Free PMC Article
Necrotizing enterocolitis: It's not all in the gut.
Meister AL, Doheny KK, Travagli RA
Exp Biol Med (Maywood) 2020 Jan;245(2):85-95. Epub 2019 Dec 6 doi: 10.1177/1535370219891971. PMID: 31810384Free PMC Article
Heart Disease in Children.
Garcia RU, Peddy SB
Prim Care 2018 Mar;45(1):143-154. doi: 10.1016/j.pop.2017.10.005. PMID: 29406940

Therapy

The effect of oropharyngeal colostrum administration on the clinical outcomes of premature infants: A meta-analysis.
Fu ZY, Huang C, Lei L, Chen LC, Wei LJ, Zhou J, Tao M, Quan MT, Huang Y
Int J Nurs Stud 2023 Aug;144:104527. Epub 2023 May 19 doi: 10.1016/j.ijnurstu.2023.104527. PMID: 37295286
Effects of kangaroo mother care on feeding intolerance in preterm infants.
Çaka SY, Topal S, Yurttutan S, Aytemiz S, Çıkar Y, Sarı M
J Trop Pediatr 2023 Feb 6;69(2) doi: 10.1093/tropej/fmad015. PMID: 36897067Free PMC Article
Nutrition in acute pancreatitis: when, what and how.
Fostier R, Arvanitakis M, Gkolfakis P
Curr Opin Clin Nutr Metab Care 2022 Sep 1;25(5):325-328. Epub 2022 Jul 5 doi: 10.1097/MCO.0000000000000851. PMID: 35787593
Positive Effects of Kangaroo Mother Care on Long-Term Breastfeeding Rates, Growth, and Neurodevelopment in Preterm Infants.
Wang Y, Zhao T, Zhang Y, Li S, Cong X
Breastfeed Med 2021 Apr;16(4):282-291. Epub 2021 Feb 2 doi: 10.1089/bfm.2020.0358. PMID: 33533688
The role of magnesium sulfate (MgSO(4)) in fetal neuroprotection.
Bachnas MA, Akbar MIA, Dachlan EG, Dekker G
J Matern Fetal Neonatal Med 2021 Mar;34(6):966-978. Epub 2019 May 27 doi: 10.1080/14767058.2019.1619688. PMID: 31092073

Prognosis

The future of artificial intelligence in clinical nutrition.
Singer P, Robinson E, Raphaeli O
Curr Opin Clin Nutr Metab Care 2024 Mar 1;27(2):200-206. Epub 2023 Aug 29 doi: 10.1097/MCO.0000000000000977. PMID: 37650706
Effect of a Multi-Strain Probiotic on the Incidence and Severity of Necrotizing Enterocolitis and Feeding Intolerances in Preterm Neonates.
Sowden M, van Weissenbruch MM, Bulabula ANH, van Wyk L, Twisk J, van Niekerk E
Nutrients 2022 Aug 12;14(16) doi: 10.3390/nu14163305. PMID: 36014810Free PMC Article
Optimal Nutrition Parameters for Neonates and Infants with Congenital Heart Disease.
Luca AC, Miron IC, Mîndru DE, Curpăn AȘ, Stan RC, Țarcă E, Luca FA, Pădureț AI
Nutrients 2022 Apr 17;14(8) doi: 10.3390/nu14081671. PMID: 35458233Free PMC Article
Incidence, Risk Factors, and Clinical Consequence of Enteral Feeding Intolerance in the Mechanically Ventilated Critically Ill: An Analysis of a Multicenter, Multiyear Database.
Heyland DK, Ortiz A, Stoppe C, Patel JJ, Yeh DD, Dukes G, Chen YJ, Almansa C, Day AG
Crit Care Med 2021 Jan 1;49(1):49-59. doi: 10.1097/CCM.0000000000004712. PMID: 33148950
Necrotizing enterocolitis: It's not all in the gut.
Meister AL, Doheny KK, Travagli RA
Exp Biol Med (Maywood) 2020 Jan;245(2):85-95. Epub 2019 Dec 6 doi: 10.1177/1535370219891971. PMID: 31810384Free PMC Article

Clinical prediction guides

The future of artificial intelligence in clinical nutrition.
Singer P, Robinson E, Raphaeli O
Curr Opin Clin Nutr Metab Care 2024 Mar 1;27(2):200-206. Epub 2023 Aug 29 doi: 10.1097/MCO.0000000000000977. PMID: 37650706
Gastrointestinal function in critically ill patients.
Reintam Blaser A, Bachmann KF, Deane AM
Curr Opin Clin Nutr Metab Care 2023 Sep 1;26(5):463-469. Epub 2023 Jun 19 doi: 10.1097/MCO.0000000000000955. PMID: 37389469
Enteral Nutrition in Term Infants with Congenital Heart Disease: Knowledge Gaps and Future Directions to Improve Clinical Practice.
Martini S, Beghetti I, Annunziata M, Aceti A, Galletti S, Ragni L, Donti A, Corvaglia L
Nutrients 2021 Mar 13;13(3) doi: 10.3390/nu13030932. PMID: 33805775Free PMC Article
Positive Effects of Kangaroo Mother Care on Long-Term Breastfeeding Rates, Growth, and Neurodevelopment in Preterm Infants.
Wang Y, Zhao T, Zhang Y, Li S, Cong X
Breastfeed Med 2021 Apr;16(4):282-291. Epub 2021 Feb 2 doi: 10.1089/bfm.2020.0358. PMID: 33533688
Necrotizing enterocolitis: It's not all in the gut.
Meister AL, Doheny KK, Travagli RA
Exp Biol Med (Maywood) 2020 Jan;245(2):85-95. Epub 2019 Dec 6 doi: 10.1177/1535370219891971. PMID: 31810384Free PMC Article

Recent systematic reviews

Best evidence summary for prevention and management of enteral feeding intolerance in critically ill patients.
Peng F, Wang H, Li J, Ma M, Jiang X, Run H, Li Q, Leng J, Xiao L, Tang L
J Clin Nurs 2024 Mar;33(3):781-796. Epub 2023 Nov 22 doi: 10.1111/jocn.16934. PMID: 37994227
Comparative efficacy and safety of caffeine citrate and aminophylline in treating apnea of prematurity: A systematic review and meta-analysis.
Miao Y, Zhou Y, Zhao S, Liu W, Wang A, Zhang Y, Li Y, Jiang H
PLoS One 2022;17(9):e0274882. Epub 2022 Sep 19 doi: 10.1371/journal.pone.0274882. PMID: 36121807Free PMC Article
A systematic review of the definitions and prevalence of feeding intolerance in preterm infants.
Weeks CL, Marino LV, Johnson MJ
Clin Nutr 2021 Nov;40(11):5576-5586. Epub 2021 Sep 17 doi: 10.1016/j.clnu.2021.09.010. PMID: 34656954
Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine.
Reintam Blaser A, Preiser JC, Fruhwald S, Wilmer A, Wernerman J, Benstoem C, Casaer MP, Starkopf J, van Zanten A, Rooyackers O, Jakob SM, Loudet CI, Bear DE, Elke G, Kott M, Lautenschläger I, Schäper J, Gunst J, Stoppe C, Nobile L, Fuhrmann V, Berger MM, Oudemans-van Straaten HM, Arabi YM, Deane AM; Working Group on Gastrointestinal Function within the Section of Metabolism, Endocrinology and Nutrition (MEN Section) of ESICM
Crit Care 2020 May 15;24(1):224. doi: 10.1186/s13054-020-02889-4. PMID: 32414423Free PMC Article
The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials.
Lewis K, Alqahtani Z, Mcintyre L, Almenawer S, Alshamsi F, Rhodes A, Evans L, Angus DC, Alhazzani W
Crit Care 2016 Aug 15;20(1):259. doi: 10.1186/s13054-016-1441-z. PMID: 27527069Free PMC Article

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