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Uterine polyp

MedGen UID:
57628
•Concept ID:
C0156369
•
Neoplastic Process
Synonyms: endometrial/uterine polyp; Intrauterine polyp; Polyp of corpus uteri; polyp of corpus uteri; Polyp of the Uterus; polyp of the uterus; Polyp of Uterus; polyp of uterus; polyp, uterus; Uterine Polyp; uterine polyp; Uterus Polyp; uterus polyp
SNOMED CT: Intrauterine polyp (11314008); Polyp of corpus uteri (11314008); Uterine polyp (11314008)
 
Monarch Initiative: MONDO:0004701

Definition

A benign protruding lesion arising either from the endometrial cavity (endometrial polyp) or the endocervix (endocervical polyp). It may occasionally recur following complete resection. [from NCI]

Professional guidelines

PubMed

Evaluation and management of abnormal uterine bleeding.
Achanna KS, Nanda J
Med J Malaysia 2022 May;77(3):374-383. PMID: 35638495
Endometrial polyps. An evidence-based diagnosis and management guide.
Vitale SG, Haimovich S, Laganà AS, Alonso L, Di Spiezio Sardo A, Carugno J; From the Global Community of Hysteroscopy Guidelines Committee
Eur J Obstet Gynecol Reprod Biol 2021 May;260:70-77. Epub 2021 Mar 13 doi: 10.1016/j.ejogrb.2021.03.017. PMID: 33756339
Evaluation and Management of Abnormal Uterine Bleeding.
Marnach ML, Laughlin-Tommaso SK
Mayo Clin Proc 2019 Feb;94(2):326-335. doi: 10.1016/j.mayocp.2018.12.012. PMID: 30711128

Recent clinical studies

Etiology

Nonelectric shaving of endometrial polyp by hysteroscopy - A new technique to eliminate thermal damage.
Sharon A, Zidane M, Aiob A, Apel-Sarid L, Bornstein J
Eur J Obstet Gynecol Reprod Biol 2023 Jun;285:170-174. Epub 2023 Apr 27 doi: 10.1016/j.ejogrb.2023.04.018. PMID: 37146506
ESTIMATION OF RELATIVE RISK OF DEVELOPMENT AND INFORMATIVENESS OF DIAGNOSTIC METHODS OF HYPERPROLIFERATIVE PROCESSES OF ENDOMETRIUM.
Boychuk AV, Vereshchahina TV, Nikitina IM
Wiad Lek 2020;73(9 cz. 2):2004-2009. PMID: 33148849
A randomised controlled trial of Outpatient versus inpatient Polyp Treatment (OPT) for abnormal uterine bleeding.
Clark TJ, Middleton LJ, Cooper NA, Diwakar L, Denny E, Smith P, Gennard L, Stobert L, Roberts TE, Cheed V, Bingham T, Jowett S, Brettell E, Connor M, Jones SE, Daniels JP
Health Technol Assess 2015 Jul;19(61):1-194. doi: 10.3310/hta19610. PMID: 26240949Free PMC Article
Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study.
Cooper NA, Clark TJ, Middleton L, Diwakar L, Smith P, Denny E, Roberts T, Stobert L, Jowett S, Daniels J; OPT Trial Collaborative Group
BMJ 2015 Mar 23;350:h1398. doi: 10.1136/bmj.h1398. PMID: 25801579Free PMC Article
Some minor female reproductive system disorders: findings in the Oxford-Family Planning Association contraceptive study.
Vessey M, Yeates D
J Fam Plann Reprod Health Care 2009 Apr;35(2):105-10. doi: 10.1783/147118909787931988. PMID: 19356282

Diagnosis

Uterine embryonal rhabdomyosarcoma in adult women: a case report on the challenging diagnosis and treatment.
Pop CF, Stanciu-Pop CM, Jungels C, Chintinne M, Artigas Guix C, Grosu F, Juravle C, Veys I
Rom J Morphol Embryol 2023 Jan-Mar;64(1):83-88. doi: 10.47162/RJME.64.1.10. PMID: 37128795Free PMC Article
Metastatic malignant melanoma in an endometrial polyp.
Ulmer K, Powers J, Alrwashdeh A, Hardy-Fairbanks A
Dermatol Online J 2021 Apr 15;27(4) PMID: 33999583
Two-Step Office-Based Hysteroscopic Operation for Submucosal Myoma.
Oh ST, Ryu HK
JSLS 2019 Jul-Sep;23(3) doi: 10.4293/JSLS.2019.00028. PMID: 31488942Free PMC Article
Clinicopathological and immunohistochemical features of uterine adenomyomatous polyps.
Strickland KC, Yuan L, Quade BJ, Nucci MR, Howitt BE
Hum Pathol 2019 Feb;84:239-245. Epub 2018 Oct 16 doi: 10.1016/j.humpath.2018.10.002. PMID: 30339971
Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study.
Cooper NA, Clark TJ, Middleton L, Diwakar L, Smith P, Denny E, Roberts T, Stobert L, Jowett S, Daniels J; OPT Trial Collaborative Group
BMJ 2015 Mar 23;350:h1398. doi: 10.1136/bmj.h1398. PMID: 25801579Free PMC Article

Therapy

Nonelectric shaving of endometrial polyp by hysteroscopy - A new technique to eliminate thermal damage.
Sharon A, Zidane M, Aiob A, Apel-Sarid L, Bornstein J
Eur J Obstet Gynecol Reprod Biol 2023 Jun;285:170-174. Epub 2023 Apr 27 doi: 10.1016/j.ejogrb.2023.04.018. PMID: 37146506
Prediction of endometrial cancer recurrence by using a novel machine learning algorithm: An Israeli gynecologic oncology group study.
Houri O, Gil Y, Gemer O, Helpman L, Vaknin Z, Lavie O, Arie AB, Amit A, Levy T, Namazov A, Shachar IB, Atlas I, Bruchim I, Eitan R
J Gynecol Obstet Hum Reprod 2022 Nov;51(9):102466. Epub 2022 Aug 28 doi: 10.1016/j.jogoh.2022.102466. PMID: 36041694
Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study.
Cooper NA, Clark TJ, Middleton L, Diwakar L, Smith P, Denny E, Roberts T, Stobert L, Jowett S, Daniels J; OPT Trial Collaborative Group
BMJ 2015 Mar 23;350:h1398. doi: 10.1136/bmj.h1398. PMID: 25801579Free PMC Article
Some minor female reproductive system disorders: findings in the Oxford-Family Planning Association contraceptive study.
Vessey M, Yeates D
J Fam Plann Reprod Health Care 2009 Apr;35(2):105-10. doi: 10.1783/147118909787931988. PMID: 19356282
Adverse effects of phytoestrogens on reproductive health: a report of three cases.
Chandrareddy A, Muneyyirci-Delale O, McFarlane SI, Murad OM
Complement Ther Clin Pract 2008 May;14(2):132-5. Epub 2008 Mar 7 doi: 10.1016/j.ctcp.2008.01.002. PMID: 18396257

Prognosis

Uterine embryonal rhabdomyosarcoma in adult women: a case report on the challenging diagnosis and treatment.
Pop CF, Stanciu-Pop CM, Jungels C, Chintinne M, Artigas Guix C, Grosu F, Juravle C, Veys I
Rom J Morphol Embryol 2023 Jan-Mar;64(1):83-88. doi: 10.47162/RJME.64.1.10. PMID: 37128795Free PMC Article
Can endometrial thickness at baseline or maximum stimulated levels during IVF predict the presence of endometrial polyps in women with two failed embryo transfers?
Hussaini S, Nayot D, Hartman M, Dahan MH
Arch Gynecol Obstet 2023 May;307(5):1645-1653. Epub 2022 Jun 9 doi: 10.1007/s00404-022-06646-6. PMID: 35680687
Prediction of endometrial cancer recurrence by using a novel machine learning algorithm: An Israeli gynecologic oncology group study.
Houri O, Gil Y, Gemer O, Helpman L, Vaknin Z, Lavie O, Arie AB, Amit A, Levy T, Namazov A, Shachar IB, Atlas I, Bruchim I, Eitan R
J Gynecol Obstet Hum Reprod 2022 Nov;51(9):102466. Epub 2022 Aug 28 doi: 10.1016/j.jogoh.2022.102466. PMID: 36041694
Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study.
Cooper NA, Clark TJ, Middleton L, Diwakar L, Smith P, Denny E, Roberts T, Stobert L, Jowett S, Daniels J; OPT Trial Collaborative Group
BMJ 2015 Mar 23;350:h1398. doi: 10.1136/bmj.h1398. PMID: 25801579Free PMC Article
The natural course of endometrial polyps: could they vanish when left untreated?
Haimov-Kochman R, Deri-Hasid R, Hamani Y, Voss E
Fertil Steril 2009 Aug;92(2):828.e11-2. Epub 2009 Jun 13 doi: 10.1016/j.fertnstert.2009.04.054. PMID: 19524890

Clinical prediction guides

Can endometrial thickness at baseline or maximum stimulated levels during IVF predict the presence of endometrial polyps in women with two failed embryo transfers?
Hussaini S, Nayot D, Hartman M, Dahan MH
Arch Gynecol Obstet 2023 May;307(5):1645-1653. Epub 2022 Jun 9 doi: 10.1007/s00404-022-06646-6. PMID: 35680687
Prediction of endometrial cancer recurrence by using a novel machine learning algorithm: An Israeli gynecologic oncology group study.
Houri O, Gil Y, Gemer O, Helpman L, Vaknin Z, Lavie O, Arie AB, Amit A, Levy T, Namazov A, Shachar IB, Atlas I, Bruchim I, Eitan R
J Gynecol Obstet Hum Reprod 2022 Nov;51(9):102466. Epub 2022 Aug 28 doi: 10.1016/j.jogoh.2022.102466. PMID: 36041694
Some minor female reproductive system disorders: findings in the Oxford-Family Planning Association contraceptive study.
Vessey M, Yeates D
J Fam Plann Reprod Health Care 2009 Apr;35(2):105-10. doi: 10.1783/147118909787931988. PMID: 19356282

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