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Menometrorrhagia

MedGen UID:: 534930
•Concept ID:: C0232943
•: Sign or Symptom

Synonyms:	Intermenstrual heavy bleeding; Metromenorrhagia
SNOMED CT:	Menometrorrhagia (314631008); Metromenorrhagia (314631008); Intermenstrual heavy bleeding (351814001)

HPO:	HP:0400008

Definition

Prolonged/excessive menses and bleeding at irregular intervals. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMenometrorrhagia

Congenital Systemic Disorder
- Abnormality of the genitourinary system
  - Abnormality of the genital system
    - Abnormality of reproductive system physiology
      - Abnormal female reproductive system physiology
        Abnormality of the menstrual cycle
        Menometrorrhagia

Professional guidelines

PubMed

The Rationale for Photobiomodulation Therapy of Vaginal Tissue for Treatment of Genitourinary Syndrome of Menopause: An Analysis of Its Mechanism of Action, and Current Clinical Outcomes.

Lanzafame RJ, de la Torre S, Leibaschoff GH
Photobiomodul Photomed Laser Surg 2019 Jul;37(7):395-407. Epub 2019 Jun 17 doi: 10.1089/photob.2019.4618. PMID: 31210575 Free PMC Article

Place of ulipristal acetate in the management of uterine fibroids: Preoperative treatment or sequential treatment?

Pourcelot AG, Capmas P, Fernandez H
J Gynecol Obstet Hum Reprod 2017 Mar;46(3):249-254. Epub 2017 Feb 3 doi: 10.1016/j.jogoh.2017.02.001. PMID: 28403922

The management of iron deficiency in menometrorrhagia.

Palacios S
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1126-30. doi: 10.3109/09513590.2012.636916. PMID: 22182056

See all (16)

Recent clinical studies

Etiology

PALM-COEIN Nomenclature for Abnormal Uterine Bleeding.

Deneris A
J Midwifery Womens Health 2016 May;61(3):376-9. Epub 2016 Mar 11 doi: 10.1111/jmwh.12440. PMID: 26969858

Endocervical Atypical Polypoid Adenomyoma.

Protopapas A, Sotiropoulou M, Athanasiou S, Loutradis D
J Minim Invasive Gynecol 2016 Jan;23(1):130-2. Epub 2015 Aug 22 doi: 10.1016/j.jmig.2015.08.879. PMID: 26304721

Menometrorrhagia during the premenopause: an overview.

Donnez J
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1114-9. doi: 10.3109/09513590.2012.637341. PMID: 22182054

GnRH-agonists in fertility preservation.

Blumenfeld Z
Curr Opin Endocrinol Diabetes Obes 2008 Dec;15(6):523-8. doi: 10.1097/MED.0b013e32831a46e9. PMID: 18971681

Intrauterine devices.

Burkman RT
Curr Opin Obstet Gynecol 1991 Aug;3(4):482-5. PMID: 1878504

See all (92)

Diagnosis

Abnormal uterine bleeding in adolescents.

Kabra R, Fisher M
Curr Probl Pediatr Adolesc Health Care 2022 May;52(5):101185. Epub 2022 May 4 doi: 10.1016/j.cppeds.2022.101185. PMID: 35525787

Pathology and Pathogenesis of Adenomyosis.

Antero MF, Ayhan A, Segars J, Shih IM
Semin Reprod Med 2020 May;38(2-03):108-118. Epub 2020 Oct 20 doi: 10.1055/s-0040-1718922. PMID: 33080632 Free PMC Article

Menometrorrhagia during the premenopause: an overview.

Donnez J
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1114-9. doi: 10.3109/09513590.2012.637341. PMID: 22182054

Update on the management of menometrorrhagia: new surgical approaches.

Fernandez H
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1131-6. Epub 2011 Dec 1 doi: 10.3109/09513590.2011.634261. PMID: 22132902

Hysteroscopy and adenocarcinoma.

Mencaglia L
Obstet Gynecol Clin North Am 1995 Sep;22(3):573-9. PMID: 8524538

See all (110)

Therapy

The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports.

Costanzi F, De Marco MP, Colombrino C, Ciancia M, Torcia F, Ruscito I, Bellati F, Frega A, Cozza G, Caserta D
Eur Rev Med Pharmacol Sci 2021 May;25(9):3432-3439. doi: 10.26355/eurrev_202105_25823. PMID: 34002816

The management of iron deficiency in menometrorrhagia.

Palacios S
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1126-30. doi: 10.3109/09513590.2012.636916. PMID: 22182056

Current and future medical treatments for menometrorrhagia during the premenopause.

Bouchard P
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1120-5. doi: 10.3109/09513590.2012.638754. PMID: 22182055

GnRH-agonists in fertility preservation.

Blumenfeld Z
Curr Opin Endocrinol Diabetes Obes 2008 Dec;15(6):523-8. doi: 10.1097/MED.0b013e32831a46e9. PMID: 18971681

Clinical decision making regarding leiomyomata: what we need in the next millenium.

Haney AF
Environ Health Perspect 2000 Oct;108 Suppl 5:835-9. doi: 10.1289/ehp.00108s5835. PMID: 11035991

See all (78)

Prognosis

Critical iron deficiency anemia with record low hemoglobin: a case report.

Chai AL, Huang OY, Rakočević R, Chung P
J Med Case Rep 2021 Sep 13;15(1):472. doi: 10.1186/s13256-021-03024-9. PMID: 34517883 Free PMC Article

Incidence of occult malignancies identified during hysterectomies performed for benign indications.

Topdagi Yilmaz EP, Cimilli Senocak GN, Topdagi YE, Aynaoglu Yildiz G, Kumtepe Y
J Gynecol Obstet Hum Reprod 2020 Mar;49(3):101620. Epub 2019 Aug 23 doi: 10.1016/j.jogoh.2019.08.003. PMID: 31449888

Thyroid Function Screening in Children and Adolescents With Mood and Anxiety Disorders.

Luft MJ, Aldrich SL, Poweleit E, Prows CA, Martin LJ, DelBello MP, Keeshin BR, Ramsey LB, Strawn JR
J Clin Psychiatry 2019 Aug 6;80(5) doi: 10.4088/JCP.18m12626. PMID: 31390496

Endocervical Atypical Polypoid Adenomyoma.

Protopapas A, Sotiropoulou M, Athanasiou S, Loutradis D
J Minim Invasive Gynecol 2016 Jan;23(1):130-2. Epub 2015 Aug 22 doi: 10.1016/j.jmig.2015.08.879. PMID: 26304721

Uterine leiomyoma causing menometrorrhagia with a concomitant mature teratoma in a 15-year-old child: a case report and review of the literature.

Naiditch JA, Milad MP, Rowell EE
J Pediatr Surg 2011 Oct;46(10):E33-6. doi: 10.1016/j.jpedsurg.2011.06.031. PMID: 22008360

See all (39)

Clinical prediction guides

The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports.

Thyroid Function Screening in Children and Adolescents With Mood and Anxiety Disorders.

Luft MJ, Aldrich SL, Poweleit E, Prows CA, Martin LJ, DelBello MP, Keeshin BR, Ramsey LB, Strawn JR
J Clin Psychiatry 2019 Aug 6;80(5) doi: 10.4088/JCP.18m12626. PMID: 31390496

Place of ulipristal acetate in the management of uterine fibroids: Preoperative treatment or sequential treatment?

Pourcelot AG, Capmas P, Fernandez H
J Gynecol Obstet Hum Reprod 2017 Mar;46(3):249-254. Epub 2017 Feb 3 doi: 10.1016/j.jogoh.2017.02.001. PMID: 28403922

Clinical and paraclinical study regarding the macro- and microscopic diagnosis of various anatomo-clinical forms of operated uterine fibromyoma.

Vaniova Klimentova D, Brăila AD, Simionescu C, Ilie I, Brăila MB
Rom J Morphol Embryol 2012;53(2):369-73. PMID: 22732808

Current and future medical treatments for menometrorrhagia during the premenopause.

Bouchard P
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1120-5. doi: 10.3109/09513590.2012.638754. PMID: 22182055

See all (46)

Recent systematic reviews

The efficacy and safety of JAK inhibitors in patients with adult-onset still's disease: A meta-analysis and systematic review.

Liao J, Tang Q, Xie X, Zhou B, Li F, Li S
Int Immunopharmacol 2024 Aug 20;137:112451. Epub 2024 Jun 12 doi: 10.1016/j.intimp.2024.112451. PMID: 38870881

A systematic review: endometriosis presenting with ascites.

Gungor T, Kanat-Pektas M, Ozat M, Zayifoglu Karaca M
Arch Gynecol Obstet 2011 Mar;283(3):513-8. Epub 2010 Sep 7 doi: 10.1007/s00404-010-1664-1. PMID: 20821226

See all (2)

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Menometrorrhagia

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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