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Skin infection

MedGen UID:
52365
•Concept ID:
C0037278
•
Disease or Syndrome
Synonyms: Disease, Infectious Skin; Diseases, Infectious Skin; Infectious Skin Disease; Infectious Skin Diseases; Skin Disease, Infectious; Skin Diseases, Infectious
SNOMED CT: Infection of skin (108365000)
 
Monarch Initiative: MONDO:0021201

Definition

An inflammatory process affecting the skin, caused by bacteria, viruses, parasites, or fungi. Examples of bacterial infection include carbuncles, furuncles, impetigo, erysipelas, and abscesses. Examples of viral infection include shingles, warts, molluscum contagiosum, and pityriasis rosea. Examples of parasitic infection include scabies and lice. Examples of fungal infection include athlete''s foot, yeast infection, and ringworm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin infection

Professional guidelines

PubMed

Septic Arthritis: Diagnosis and Treatment.
Earwood JS, Walker TR, Sue GJC
Am Fam Physician 2021 Dec 1;104(6):589-597. PMID: 34913662
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Impetigo: diagnosis and treatment.
Hartman-Adams H, Banvard C, Juckett G
Am Fam Physician 2014 Aug 15;90(4):229-35. PMID: 25250996

Recent clinical studies

Etiology

American Academy of Dermatology Guidelines: Awareness of comorbidities associated with atopic dermatitis in adults.
Davis DMR, Drucker AM, Alikhan A, Bercovitch L, Cohen DE, Darr JM, Eichenfield LF, Frazer-Green L, Paller AS, Silverberg JI, Singh AM, Sidbury R
J Am Acad Dermatol 2022 Jun;86(6):1335-1336.e18. Epub 2022 Jan 24 doi: 10.1016/j.jaad.2022.01.009. PMID: 35085682
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Staphylococcal Skin and Soft Tissue Infections.
Hatlen TJ, Miller LG
Infect Dis Clin North Am 2021 Mar;35(1):81-105. Epub 2020 Dec 7 doi: 10.1016/j.idc.2020.10.003. PMID: 33303329
Emerging Cutaneous Phaeohyphomycosis Caused by Alternaria infectoria.
Kieselová K, Gomes T, Santiago F, Martinha H
Acta Med Port 2021 Nov 2;34(11):774-778. Epub 2020 Oct 12 doi: 10.20344/amp.13496. PMID: 33054931
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771

Diagnosis

Pitted keratolysis.
Palaniappan V, Murthy AB, Karthikeyan K
Clin Exp Dermatol 2023 Aug 25;48(9):978-983. doi: 10.1093/ced/llad175. PMID: 37151115
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Staphylococcal Skin and Soft Tissue Infections.
Hatlen TJ, Miller LG
Infect Dis Clin North Am 2021 Mar;35(1):81-105. Epub 2020 Dec 7 doi: 10.1016/j.idc.2020.10.003. PMID: 33303329
Impetigo: diagnosis and treatment.
Hartman-Adams H, Banvard C, Juckett G
Am Fam Physician 2014 Aug 15;90(4):229-35. PMID: 25250996
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771

Therapy

Medical Complications of Tattoos: A Comprehensive Review.
Islam PS, Chang C, Selmi C, Generali E, Huntley A, Teuber SS, Gershwin ME
Clin Rev Allergy Immunol 2016 Apr;50(2):273-86. doi: 10.1007/s12016-016-8532-0. PMID: 26940693
Common Skin Rashes in Children.
Allmon A, Deane K, Martin KL
Am Fam Physician 2015 Aug 1;92(3):211-6. PMID: 26280141
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.
Beck LA, Thaçi D, Hamilton JD, Graham NM, Bieber T, Rocklin R, Ming JE, Ren H, Kao R, Simpson E, Ardeleanu M, Weinstein SP, Pirozzi G, Guttman-Yassky E, Suárez-Fariñas M, Hager MD, Stahl N, Yancopoulos GD, Radin AR
N Engl J Med 2014 Jul 10;371(2):130-9. doi: 10.1056/NEJMoa1314768. PMID: 25006719
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771
Immunosuppression and skin infection.
Savin JA, Noble WC
Br J Dermatol 1975 Jul;93(1):115-20. doi: 10.1111/j.1365-2133.1975.tb06488.x. PMID: 172102

Prognosis

Review: Emergomycosis.
Reddy DL, Nel J, Govender NP
J Mycol Med 2023 Mar;33(1):101313. Epub 2022 Jul 23 doi: 10.1016/j.mycmed.2022.101313. PMID: 36272380
Septic Arthritis: Diagnosis and Treatment.
Earwood JS, Walker TR, Sue GJC
Am Fam Physician 2021 Dec 1;104(6):589-597. PMID: 34913662
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Common Skin Rashes in Children.
Allmon A, Deane K, Martin KL
Am Fam Physician 2015 Aug 1;92(3):211-6. PMID: 26280141
Impetigo: diagnosis and treatment.
Hartman-Adams H, Banvard C, Juckett G
Am Fam Physician 2014 Aug 15;90(4):229-35. PMID: 25250996

Clinical prediction guides

State transitions across the Strep A disease spectrum: scoping review and evidence gaps.
Parajulee P, Lee JS, Abbas K, Cannon J, Excler JL, Kim JH, Mogasale V
BMC Infect Dis 2024 Jan 19;24(1):108. doi: 10.1186/s12879-023-08888-4. PMID: 38243271Free PMC Article
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Frequency and Predictors of Suboptimal Prescribing Among a Cohort of Older Male Residents with Urinary Tract Infections.
Appaneal HJ, Caffrey AR, Lopes VV, Dosa DM, Shireman TI, LaPlante KL
Clin Infect Dis 2021 Nov 2;73(9):e2763-e2772. doi: 10.1093/cid/ciaa874. PMID: 32590839
Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis.
Simpson EL Md McR, Irvine AD Md, Eichenfield LF Md, Friedlander SF Md
Semin Cutan Med Surg 2016 Jun;35(5 Suppl):S84-8. doi: 10.12788/j.sder.2016.041. PMID: 27525380
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.
Beck LA, Thaçi D, Hamilton JD, Graham NM, Bieber T, Rocklin R, Ming JE, Ren H, Kao R, Simpson E, Ardeleanu M, Weinstein SP, Pirozzi G, Guttman-Yassky E, Suárez-Fariñas M, Hager MD, Stahl N, Yancopoulos GD, Radin AR
N Engl J Med 2014 Jul 10;371(2):130-9. doi: 10.1056/NEJMoa1314768. PMID: 25006719

Recent systematic reviews

American Academy of Dermatology Guidelines: Awareness of comorbidities associated with atopic dermatitis in adults.
Davis DMR, Drucker AM, Alikhan A, Bercovitch L, Cohen DE, Darr JM, Eichenfield LF, Frazer-Green L, Paller AS, Silverberg JI, Singh AM, Sidbury R
J Am Acad Dermatol 2022 Jun;86(6):1335-1336.e18. Epub 2022 Jan 24 doi: 10.1016/j.jaad.2022.01.009. PMID: 35085682
Skin care interventions in infants for preventing eczema and food allergy.
Kelleher MM, Cro S, Cornelius V, Lodrup Carlsen KC, Skjerven HO, Rehbinder EM, Lowe AJ, Dissanayake E, Shimojo N, Yonezawa K, Ohya Y, Yamamoto-Hanada K, Morita K, Axon E, Surber C, Cork M, Cooke A, Tran L, Van Vogt E, Schmitt J, Weidinger S, McClanahan D, Simpson E, Duley L, Askie LM, Chalmers JR, Williams HC, Boyle RJ
Cochrane Database Syst Rev 2021 Feb 5;2(2):CD013534. doi: 10.1002/14651858.CD013534.pub2. PMID: 33545739Free PMC Article
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771
Systematic review of tattoo-associated skin infection with rapidly growing mycobacteria and public health investigation of a cluster in Scotland, 2010.
Conaglen PD, Laurenson IF, Sergeant A, Thorn SN, Rayner A, Stevenson J
Euro Surveill 2013 Aug 8;18(32):20553. doi: 10.2807/1560-7917.es2013.18.32.20553. PMID: 23968828
Evidence-based diagnostics: adult septic arthritis.
Carpenter CR, Schuur JD, Everett WW, Pines JM
Acad Emerg Med 2011 Aug;18(8):781-96. doi: 10.1111/j.1553-2712.2011.01121.x. PMID: 21843213Free PMC Article

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