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DNA Virus Infections

MedGen UID:: 41636
•Concept ID:: C0012922
•: Disease or Syndrome

Synonyms:

DNA Virus Infection; Infection, DNA Virus; Infections, DNA Virus; Virus Infection, DNA; Virus Infections, DNA

Definition

Diseases caused by DNA VIRUSES. [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDNA Virus Infections

Pathological Conditions, Signs and Symptoms
- Clinical finding
  - Finding by Cause
    - Infection
      - viral disease
        DNA Virus Infections
        Adenoviridae infectious disease
        Adenovirus Infections, Human
        Canine Hepatitides, Infectious
        Recurrent Adenovirus Infection
        Refractory Adenovirus Infection
        African Swine Fever
        Disease caused by Circoviridae
        Porcine Postweaning Multisystemic Wasting Syndrome
        Disease caused by Parvoviridae
        Aleutian disease
        Erythema infectiosum
        Feline Panleukopenia
        Mink Viral Enteritis
        Disease caused by Poxviridae
        Contagious pustular dermatitis
        Cowpox
        Fowlpox
        Infectious Ectromelia
        Lumpy skin disease
        Molluscum contagiosum
        Disseminated molluscum contagiosum
        Mpox
        Myxomatosis, Infectious
        Smallpox
        Modified smallpox
        Variola minor infection
        Vaccinia
        Hepadnaviridae infectious disease
        Hepatitis B virus infection
        Chronic hepatitis B virus infection
        Current Hepatitis B Infection
        Herpesvirus infection
        Bovine Rhinotracheitis, Infectious
        Catarrhal Fever, Malignant
        Cytomegalovirus infection
        Acquired Cytomegaloviral Infection
        Congenital cytomegalovirus infection
        Current Cytomegalovirus Infection
        Cytomegaloviral gastritis
        Cytomegalovirus colitis
        Cytomegalovirus Gastroenteritis
        Cytomegalovirus pneumonia
        Cytomegalovirus retinitis
        Esophagitis caused by Cytomegalovirus
        Recurrent Cytomegalovirus Infection
        Refractory Cytomegalovirus Infection
        Epstein-Barr virus infection
        Burkitt lymphoma
        Chronic Active EBV Disease
        Current EBV Infection
        Infectious mononucleosis
        Oral hairy leukoplakia
        Recurrent EBV Infection
        Severe Chronic Active EBV Infection
        Facial palsy
        Bilateral facial palsy
        Facial diplegia
        Unilateral facial palsy
        Herpes simplex encephalitis
        Herpes simplex infectious disease
        Genital herpes
        Herpes labialis
        Herpes simplex virus keratitis
        Herpes stomatitis
        Herpetic vulvovaginitis
        Kaposi varicelliform eruption
        Neonatal Herpes Simplex Infection
        Human herpesvirus 8 infection
        Infection by human herpesvirus 6
        Kaposi sarcoma
        AIDS-Related Kaposi Sarcoma
        Cardiac Kaposi Sarcoma
        Central Nervous System Kaposi Sarcoma
        Conjunctival Kaposi Sarcoma
        Corneal Kaposi Sarcoma
        Digestive System Kaposi Sarcoma
        Endemic African Kaposi Sarcoma
        Iatrogenic Kaposi sarcoma
        Kaposi Sarcoma NCI Grade 2
        Kaposi Sarcoma NCI Grade 3
        Kaposi sarcoma, susceptibility to
        Lung Kaposi Sarcoma
        Lymphadenopathic Kaposi Sarcoma
        Metastatic Kaposi Sarcoma
        Oral Cavity Kaposi Sarcoma
        Parotid Gland Kaposi Sarcoma
        Penile Kaposi Sarcoma
        Prostate Kaposi Sarcoma
        Recurrent Kaposi Sarcoma
        Refractory Kaposi Sarcoma
        Skin Kaposi Sarcoma
        Vulvar Kaposi Sarcoma
        Marek Disease
        Pseudorabies
        Roseola Infantum
        Roseolovirus infectious disease
        Exanthema subitum
        Varicella zoster infection
        Chickenpox
        Congenital Varicella Zoster Infection
        Disseminated Oka Varicella Zoster Virus Infection
        Herpes zoster
        Postvaricella encephalitis
        Human papilloma virus infection
        AIDS-Related Human Papillomavirus Infection
        Anogenital human papillomavirus infection
        Genital Human Papillomavirus Infection
        HPV16 Infection
        Verrucae
        Disseminated cutaneous warts
        Epidermodysplasia verruciformis
        Genital warts
        Oral Verruca Vulgaris
        Verruca plana
        Polyomavirus infectious disease
        Cutaneous neuroendocrine carcinoma
        Cutaneous Merkel Cell Carcinoma by AJCC v8 Stage
        Metastatic Merkel Cell Carcinoma
        Recurrent Merkel Cell Carcinoma
        Refractory Merkel Cell Carcinoma
        Unresectable Merkel Cell Carcinoma
        Vulvar Merkel Cell Carcinoma
        Progressive multifocal leukoencephalopathy

Professional guidelines

PubMed

Update on new antivirals under development for the treatment of double-stranded DNA virus infections.

Dropulic LK, Cohen JI
Clin Pharmacol Ther 2010 Nov;88(5):610-9. Epub 2010 Sep 29 doi: 10.1038/clpt.2010.178. PMID: 20881959 Free PMC Article

Ionic Contra-Viral Therapy (ICVT); a new approach to the treatment of DNA virus infections.

Hartley C, Hartley M, Pardoe I, Knight A
Arch Virol 2006 Dec;151(12):2495-501. Epub 2006 Aug 21 doi: 10.1007/s00705-006-0824-x. PMID: 16932984

Role of cidofovir in the treatment of DNA virus infections, other than CMV infections, in immunocompromised patients.

Snoeck R, De Clercq E
Curr Opin Investig Drugs 2002 Nov;3(11):1561-6. PMID: 12476953

See all (3)

Recent clinical studies

Etiology

Function and Regulation of Nuclear DNA Sensors During Viral Infection and Tumorigenesis.

Zhang F, Yuan Y, Ma F
Front Immunol 2020;11:624556. Epub 2021 Jan 11 doi: 10.3389/fimmu.2020.624556. PMID: 33505405 Free PMC Article

Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses.

Wang L, Wen M, Cao X
Science 2019 Aug 16;365(6454) Epub 2019 Jul 18 doi: 10.1126/science.aav0758. PMID: 31320558

Viral infection and atherosclerosis.

Hemmat N, Ebadi A, Badalzadeh R, Memar MY, Baghi HB
Eur J Clin Microbiol Infect Dis 2018 Dec;37(12):2225-2233. Epub 2018 Sep 5 doi: 10.1007/s10096-018-3370-z. PMID: 30187247

DNA viral infections complicating lung transplantation.

Clark NM, Lynch JP 3rd, Sayah D, Belperio JA, Fishbein MC, Weigt SS
Semin Respir Crit Care Med 2013 Jun;34(3):380-404. Epub 2013 Jul 2 doi: 10.1055/s-0033-1348473. PMID: 23821512

Viral-associated thrombotic microangiopathies.

Lopes da Silva R
Hematol Oncol Stem Cell Ther 2011;4(2):51-9. doi: 10.5144/1658-3876.2011.51. PMID: 21727765

See all (361)

Diagnosis

Infections with DNA Viruses, Adenovirus, Polyomaviruses, and Parvovirus B19 in Hematopoietic Stem Cell Transplant Recipients and Patients with Hematologic Malignancies.

Obeid KM
Infect Dis Clin North Am 2019 Jun;33(2):501-521. Epub 2019 Mar 30 doi: 10.1016/j.idc.2019.02.005. PMID: 30940465

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses.

Wang C, Guan Y, Lv M, Zhang R, Guo Z, Wei X, Du X, Yang J, Li T, Wan Y, Su X, Huang X, Jiang Z
Immunity 2018 Apr 17;48(4):675-687.e7. Epub 2018 Apr 10 doi: 10.1016/j.immuni.2018.03.017. PMID: 29653696

The Promise of Proteomics in the Study of Oncogenic Viruses.

McBride AA
Mol Cell Proteomics 2017 Apr;16(4 suppl 1):S65-S74. Epub 2017 Jan 19 doi: 10.1074/mcp.O116.065201. PMID: 28104704 Free PMC Article

Bacterial infections, DNA virus infections, and RNA virus infections manifest differently in neutrophil receptor expression.

Lilius EM, Nuutila J
ScientificWorldJournal 2012;2012:527347. Epub 2012 Mar 12 doi: 10.1100/2012/527347. PMID: 22536142 Free PMC Article

Biological terrorism.

Moran GJ, Talan DA, Abrahamian FM
Infect Dis Clin North Am 2008 Mar;22(1):145-87, vii. doi: 10.1016/j.idc.2007.12.003. PMID: 18295687 Free PMC Article

See all (196)

Therapy

Fifty Years in Search of Selective Antiviral Drugs.

De Clercq E
J Med Chem 2019 Aug 22;62(16):7322-7339. Epub 2019 Apr 12 doi: 10.1021/acs.jmedchem.9b00175. PMID: 30939009

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation.

Tzannou I, Papadopoulou A, Naik S, Leung K, Martinez CA, Ramos CA, Carrum G, Sasa G, Lulla P, Watanabe A, Kuvalekar M, Gee AP, Wu MF, Liu H, Grilley BJ, Krance RA, Gottschalk S, Brenner MK, Rooney CM, Heslop HE, Leen AM, Omer B
J Clin Oncol 2017 Nov 1;35(31):3547-3557. Epub 2017 Aug 7 doi: 10.1200/JCO.2017.73.0655. PMID: 28783452 Free PMC Article

DNA viral infections complicating lung transplantation.

Clark NM, Lynch JP 3rd, Sayah D, Belperio JA, Fishbein MC, Weigt SS
Semin Respir Crit Care Med 2013 Jun;34(3):380-404. Epub 2013 Jul 2 doi: 10.1055/s-0033-1348473. PMID: 23821512

Emerging antiviral drugs.

De Clercq E
Expert Opin Emerg Drugs 2008 Sep;13(3):393-416. doi: 10.1517/14728214.13.3.393. PMID: 18764719

Biological terrorism.

Moran GJ, Talan DA, Abrahamian FM
Infect Dis Clin North Am 2008 Mar;22(1):145-87, vii. doi: 10.1016/j.idc.2007.12.003. PMID: 18295687 Free PMC Article

See all (160)

Prognosis

Constant companion: clinical and developmental aspects of torque teno virus infections.

Lolomadze EA, Rebrikov DV
Arch Virol 2020 Dec;165(12):2749-2757. Epub 2020 Oct 10 doi: 10.1007/s00705-020-04841-x. PMID: 33040309

Bacterial infections, DNA virus infections, and RNA virus infections manifest differently in neutrophil receptor expression.

Lilius EM, Nuutila J
ScientificWorldJournal 2012;2012:527347. Epub 2012 Mar 12 doi: 10.1100/2012/527347. PMID: 22536142 Free PMC Article

SEN virus: epidemiology and characteristics of a transfusion-transmitted virus.

Akiba J, Umemura T, Alter HJ, Kojiro M, Tabor E
Transfusion 2005 Jul;45(7):1084-8. doi: 10.1111/j.1537-2995.2004.00209.x. PMID: 15987351

Vaccines against persistent DNA virus infections.

Wills MR, Carmichael AJ, Sissons JG
Br Med Bull 2002;62:125-38. doi: 10.1093/bmb/62.1.125. PMID: 12176855

TCRgammadelta cells and viruses.

Sciammas R, Bluestone JA
Microbes Infect 1999 Mar;1(3):203-12. doi: 10.1016/s1286-4579(99)80035-5. PMID: 10801231

See all (129)

Clinical prediction guides

Constant companion: clinical and developmental aspects of torque teno virus infections.

Lolomadze EA, Rebrikov DV
Arch Virol 2020 Dec;165(12):2749-2757. Epub 2020 Oct 10 doi: 10.1007/s00705-020-04841-x. PMID: 33040309

Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production.

Ghosh A, Shao L, Sampath P, Zhao B, Patel NV, Zhu J, Behl B, Parise RA, Beumer JH, O'Sullivan RJ, DeLuca NA, Thorne SH, Rathinam VAK, Li P, Sarkar SN
Immunity 2019 Jan 15;50(1):51-63.e5. Epub 2019 Jan 8 doi: 10.1016/j.immuni.2018.12.013. PMID: 30635239 Free PMC Article

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation.

Viral infections and colorectal cancer: a systematic review of epidemiological studies.

Chen H, Chen XZ, Waterboer T, Castro FA, Brenner H
Int J Cancer 2015 Jul 1;137(1):12-24. Epub 2014 Sep 17 doi: 10.1002/ijc.29180. PMID: 25186851

SEN virus: epidemiology and characteristics of a transfusion-transmitted virus.

Akiba J, Umemura T, Alter HJ, Kojiro M, Tabor E
Transfusion 2005 Jul;45(7):1084-8. doi: 10.1111/j.1537-2995.2004.00209.x. PMID: 15987351

See all (209)

Recent systematic reviews

Torque-teno virus for the prediction of graft rejection and infection disease after kidney transplantation: A systematic review and meta-analysis.

Zeng J, Tang Y, Lin T, Song T
J Med Virol 2023 Mar;95(3):e28677. doi: 10.1002/jmv.28677. PMID: 36929741

In vitro comparison of currently available and investigational antiviral agents against pathogenic human double-stranded DNA viruses: A systematic literature review.

Chemaly RF, Hill JA, Voigt S, Peggs KS
Antiviral Res 2019 Mar;163:50-58. Epub 2019 Jan 21 doi: 10.1016/j.antiviral.2019.01.008. PMID: 30677427

Cutaneous squamous cell cancer (cSCC) risk and the human leukocyte antigen (HLA) system.

Yesantharao P, Wang W, Ioannidis NM, Demehri S, Whittemore AS, Asgari MM
Hum Immunol 2017 Apr;78(4):327-335. Epub 2017 Feb 7 doi: 10.1016/j.humimm.2017.02.002. PMID: 28185865 Free PMC Article

Viral infections and colorectal cancer: a systematic review of epidemiological studies.

Chen H, Chen XZ, Waterboer T, Castro FA, Brenner H
Int J Cancer 2015 Jul 1;137(1):12-24. Epub 2014 Sep 17 doi: 10.1002/ijc.29180. PMID: 25186851

See all (4)

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