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Lung Soft Tissue Neoplasm

MedGen UID:
353872
•Concept ID:
C1708783
•
Neoplastic Process

Definition

A benign, intermediate, or malignant mesenchymal neoplasm that arises from the lung. [from NCI]

Professional guidelines

PubMed

Advances in treatment of alveolar soft part sarcoma: an updated review.
Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China.
Xu C, Si L, Wang W, Li Z, Song Z, Wang Q, Liu A, Yu J, Fang W, Zhong W, Wang Z, Zhang Y, Liu J, Zhang S, Cai X, Liu A, Li W, Zhan P, Liu H, Lv T, Miao L, Min L, Chen Y, Yuan J, Wang F, Jiang Z, Lin G, Pu X, Lin R, Liu W, Rao C, Lv D, Yu Z, Lei L, Li X, Tang C, Zhou C, Zhang J, Xue J, Guo H, Chu Q, Meng R, Wu J, Zhang R, Hu X, Zhou J, Zhu Z, Li Y, Qiu H, Xia F, Lu Y, Chen X, Ge R, Dai E, Han Y, Pan W, Luo J, Jia H, Dong X, Pang F, Wang K, Wang L, Zhu Y, Xie Y, Lin X, Cai J, Wei J, Lan F, Feng H, Wang L, Du Y, Yao W, Shi X, Niu X, Yuan D, Yao Y, Huang J, Zhang Y, Sun P, Wang H, Ye M, Wang D, Wang Z, Wan B, Lv D, Wei Q, Kang J, Zhang J, Zhang C, Yu G, Ou J, Shi L, Li Z, Liu Z, Liu J, Yang N, Wu L, Wang H, Jin G, Yang L, Wang G, Fang M, Fang Y, Li Y, Wang X, Zhang Y, Ma S, Wang B, Zhang X, Song Y, Lu Y
Thorac Cancer 2022 Nov;13(21):3084-3097. Epub 2022 Sep 20 doi: 10.1111/1759-7714.14644. PMID: 36127731Free PMC Article
DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.
Yao J, Bergsland E, Aggarwal R, Aparicio A, Beltran H, Crabtree JS, Hann CL, Ibrahim T, Byers LA, Sasano H, Umejiego J, Pavel M
Oncologist 2022 Nov 3;27(11):940-951. doi: 10.1093/oncolo/oyac161. PMID: 35983951Free PMC Article

Recent clinical studies

Etiology

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
CIC-DUX4 sarcomas.
Brahmi M, Vanacker H, Macagno N, Tirode F, Dufresne A
Curr Opin Oncol 2022 Jul 1;34(4):342-347. Epub 2022 Jun 22 doi: 10.1097/CCO.0000000000000855. PMID: 35730520
The Impact of Pazopanib on the Cardiovascular System.
Justice CN, Derbala MH, Baich TM, Kempton AN, Guo AS, Ho TH, Smith SA
J Cardiovasc Pharmacol Ther 2018 Sep;23(5):387-398. Epub 2018 Apr 29 doi: 10.1177/1074248418769612. PMID: 29706106Free PMC Article
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428

Diagnosis

Advances in treatment of alveolar soft part sarcoma: an updated review.
Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
Soft tissue limb and trunk sarcomas: diagnosis, treatment and follow-up.
Rastrelli M, Tropea S, Basso U, Roma A, Maruzzo M, Rossi CR
Anticancer Res 2014 Oct;34(10):5251-62. PMID: 25275017
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Therapy

The Impact of Pazopanib on the Cardiovascular System.
Justice CN, Derbala MH, Baich TM, Kempton AN, Guo AS, Ho TH, Smith SA
J Cardiovasc Pharmacol Ther 2018 Sep;23(5):387-398. Epub 2018 Apr 29 doi: 10.1177/1074248418769612. PMID: 29706106Free PMC Article
Eribulin in Cancer Treatment.
Swami U, Shah U, Goel S
Mar Drugs 2015 Aug 7;13(8):5016-58. doi: 10.3390/md13085016. PMID: 26262627Free PMC Article
Ridaforolimus.
Drugs R D 2010;10(3):165-78. doi: 10.2165/11586010-000000000-00000. PMID: 20945947Free PMC Article
Biricodar. Vertex Pharmaceuticals.
Dey S
Curr Opin Investig Drugs 2002 May;3(5):818-23. PMID: 12090559
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Prognosis

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
Soft tissue limb and trunk sarcomas: diagnosis, treatment and follow-up.
Rastrelli M, Tropea S, Basso U, Roma A, Maruzzo M, Rossi CR
Anticancer Res 2014 Oct;34(10):5251-62. PMID: 25275017
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Clinical prediction guides

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas.
Kao YC, Owosho AA, Sung YS, Zhang L, Fujisawa Y, Lee JC, Wexler L, Argani P, Swanson D, Dickson BC, Fletcher CDM, Antonescu CR
Am J Surg Pathol 2018 May;42(5):604-615. doi: 10.1097/PAS.0000000000000965. PMID: 29300189Free PMC Article
Soft tissue metastases in lung cancer: a review of the literature.
Perisano C, Spinelli MS, Graci C, Scaramuzzo L, Marzetti E, Barone C, Fabbriciani C, Maccauro G
Eur Rev Med Pharmacol Sci 2012 Dec;16(14):1908-14. PMID: 23242715
Metallothioneins and cancer.
Eckschlager T, Adam V, Hrabeta J, Figova K, Kizek R
Curr Protein Pept Sci 2009 Aug;10(4):360-75. doi: 10.2174/138920309788922243. PMID: 19689357
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428

Recent systematic reviews

Identifying the primary tumour in patients with cancer of unknown primary (CUP) using [(18)F]FDG PET/CT: a systematic review and individual patient data meta-analysis.
Willemse JRJ, Lambregts DMJ, Balduzzi S, Schats W, Snaebjornsson P, Marchetti S, Vollebergh MA, van Golen LW, Cheung Z, Vogel WV, Bodalal Z, Rostami S, Gerke O, Sivakumaran T, Beets-Tan RGH, Lahaye MJ
Eur J Nucl Med Mol Imaging 2024 Dec;52(1):225-236. Epub 2024 Aug 14 doi: 10.1007/s00259-024-06860-1. PMID: 39141069Free PMC Article
Clinical outcomes of brain metastasectomy from soft tissue and bone sarcomas: a systematic review.
Wang Y, Delisle M, Smith D, Alshamsan B, Srikanthan A
Int J Clin Oncol 2022 Nov;27(11):1767-1779. Epub 2022 Aug 22 doi: 10.1007/s10147-022-02227-4. PMID: 35994183
A systematic review and meta-analysis of outcomes after acute limb ischemia in patients with cancer.
Govsyeyev N, Malgor RD, Hoffman C, Harroun N, Sturman E, Al-Musawi M, Malgor EA, Jacobs DL, Nehler M
J Vasc Surg 2021 Sep;74(3):1033-1040.e1. Epub 2021 Apr 24 doi: 10.1016/j.jvs.2021.03.058. PMID: 33905869
High frequency of lobular breast cancer in distant metastases to the orbit.
Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, Lehmann U, Kreipe H, Christgen M
Cancer Med 2015 Jan;4(1):104-11. Epub 2014 Oct 30 doi: 10.1002/cam4.331. PMID: 25355547Free PMC Article
Risk of gastrointestinal events with sorafenib, sunitinib and pazopanib in patients with solid tumors: a systematic review and meta-analysis of clinical trials.
Santoni M, Conti A, De Giorgi U, Iacovelli R, Pantano F, Burattini L, Muzzonigro G, Berardi R, Santini D, Cascinu S
Int J Cancer 2014 Aug 15;135(4):763-73. Epub 2013 Nov 18 doi: 10.1002/ijc.28544. PMID: 24127298

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