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Grade 1 Colorectal Adenocarcinoma

MedGen UID:
272682
Concept ID:
C1333867
Neoplastic Process
Synonyms: Grade I Colorectal Adenocarcinoma; Low Grade Colorectal Adenocarcinoma; Well Differentiated Colorectal Adenocarcinoma

Definition

A colorectal adenocarcinoma characterized by the presence of a malignant cellular infiltrate with more than 95% glandular formation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Colorectal Adenocarcinoma

Professional guidelines

PubMed

Ceppa EP, Collings AT, Abdalla M, Onkendi E, Nelson DW, Ozair A, Miraflor E, Rahman F, Whiteside J, Shah MM, Ayloo S, Dirks R, Kumar SS, Ansari MT, Sucandy I, Ali K, Douglas S, Polanco PM, Vreeland TJ, Buell J, Abou-Setta AM, Awad Z, Kwon CH, Martinie JB, Sbrana F, Pryor A, Slater BJ, Richardson W, Jeyarajah R, Alseidi A
Surg Endosc 2023 Dec;37(12):8991-9000. Epub 2023 Nov 13 doi: 10.1007/s00464-023-10468-1. PMID: 37957297
Guaglio M
Ann Surg Oncol 2018 Dec;25(Suppl 3):774-775. Epub 2018 Nov 27 doi: 10.1245/s10434-018-7047-8. PMID: 30483974
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD
Gastroenterology 2013 Sep;145(3):521-36. Epub 2013 Jul 1 doi: 10.1053/j.gastro.2013.06.052. PMID: 23827861Free PMC Article

Recent clinical studies

Etiology

Xu L, Su X, He Z, Zhang C, Lu J, Zhang G, Sun Y, Du X, Chi P, Wang Z, Zhong M, Wu A, Zhu A, Li F, Xu J, Kang L, Suo J, Deng H, Ye Y, Ding K, Xu T, Zhang Z, Zheng M, Xiao Y; RELARC Study Group
Lancet Oncol 2021 Mar;22(3):391-401. Epub 2021 Feb 12 doi: 10.1016/S1470-2045(20)30685-9. PMID: 33587893
Imai J, Ichikawa H, Mizukami H, Suzuki T, Watanabe N, Mine T
Tokai J Exp Clin Med 2016 Mar 20;41(1):22-3. PMID: 27050891
Kannuna H, Rubio CA, Silverio PC, Girardin M, Goossens N, Rubbia-Brandt L, Puppa G
Diagn Pathol 2015 Jul 9;10:92. doi: 10.1186/s13000-015-0305-1. PMID: 26156870Free PMC Article
AlAmeel T, Bseiso B, AlBugami MM, AlMomen S, Roth LS
Can J Gastroenterol Hepatol 2015 Nov-Dec;29(8):423-6. Epub 2015 Jun 12 doi: 10.1155/2015/823835. PMID: 26069893Free PMC Article
de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, Boni C, Cortes-Funes H, Cervantes A, Freyer G, Papamichael D, Le Bail N, Louvet C, Hendler D, de Braud F, Wilson C, Morvan F, Bonetti A
J Clin Oncol 2000 Aug;18(16):2938-47. doi: 10.1200/JCO.2000.18.16.2938. PMID: 10944126

Diagnosis

Görgec B, Benedetti Cacciaguerra A, Lanari J, Russolillo N, Cipriani F, Aghayan D, Zimmitti G, Efanov M, Alseidi A, Mocchegiani F, Giuliante F, Ruzzenente A, Rotellar F, Fuks D, D'Hondt M, Vivarelli M, Edwin B, Aldrighetti LA, Ferrero A, Cillo U, Besselink MG, Abu Hilal M
JAMA Surg 2021 Aug 1;156(8):e212064. Epub 2021 Aug 11 doi: 10.1001/jamasurg.2021.2064. PMID: 34076671Free PMC Article
Paver EC, Cooper WA, Colebatch AJ, Ferguson PM, Hill SK, Lum T, Shin JS, O'Toole S, Anderson L, Scolyer RA, Gupta R
Pathology 2021 Feb;53(2):141-156. Epub 2020 Dec 30 doi: 10.1016/j.pathol.2020.10.007. PMID: 33388161
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM, Roodvoets AGH, Nagtegaal ID, Beets-Tan RGH, Blomqvist LK, Fokstuen T, Ten Tije AJ, Capdevila J, Hendriks MP, Edhemovic I, Cervantes A, Nilsson PJ, Glimelius B, van de Velde CJH, Hospers GAP; RAPIDO collaborative investigators
Lancet Oncol 2021 Jan;22(1):29-42. Epub 2020 Dec 7 doi: 10.1016/S1470-2045(20)30555-6. PMID: 33301740
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD
Gastroenterology 2013 Sep;145(3):521-36. Epub 2013 Jul 1 doi: 10.1053/j.gastro.2013.06.052. PMID: 23827861Free PMC Article
Smith J, Reidy-Lagunes D
Semin Oncol 2013 Feb;40(1):100-8. doi: 10.1053/j.seminoncol.2012.11.011. PMID: 23391117

Therapy

Lin ZY, Zhang P, Chi P, Xiao Y, Xu XM, Zhang AM, Qiu XF, Wu JX, Yuan Y, Wang ZN, Qu XJ, Li X, Nie X, Yang M, Cai KL, Zhang WK, Huang Y, Sun Z, Hou ZG, Ma C, Cheng FZ, Tao KX, Zhang T
Ann Oncol 2024 Oct;35(10):882-891. Epub 2024 Jul 2 doi: 10.1016/j.annonc.2024.06.015. PMID: 38964714
Thompson HM, Omer DM, Lin S, Kim JK, Yuval JB, Verheij FS, Qin LX, Gollub MJ, Wu AJ, Lee M, Patil S, Hezel AF, Marcet JE, Cataldo PA, Polite BN, Herzig DO, Liska D, Oommen S, Friel CM, Ternent CA, Coveler AL, Hunt SR, Garcia-Aguilar J; OPRA Consortium
JAMA Netw Open 2024 Jan 2;7(1):e2350903. doi: 10.1001/jamanetworkopen.2023.50903. PMID: 38194231Free PMC Article
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM, Roodvoets AGH, Nagtegaal ID, Beets-Tan RGH, Blomqvist LK, Fokstuen T, Ten Tije AJ, Capdevila J, Hendriks MP, Edhemovic I, Cervantes A, Nilsson PJ, Glimelius B, van de Velde CJH, Hospers GAP; RAPIDO collaborative investigators
Lancet Oncol 2021 Jan;22(1):29-42. Epub 2020 Dec 7 doi: 10.1016/S1470-2045(20)30555-6. PMID: 33301740
Hochster HS, Hart LL, Ramanathan RK, Childs BH, Hainsworth JD, Cohn AL, Wong L, Fehrenbacher L, Abubakr Y, Saif MW, Schwartzberg L, Hedrick E
J Clin Oncol 2008 Jul 20;26(21):3523-9. doi: 10.1200/JCO.2007.15.4138. PMID: 18640933
de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, Boni C, Cortes-Funes H, Cervantes A, Freyer G, Papamichael D, Le Bail N, Louvet C, Hendler D, de Braud F, Wilson C, Morvan F, Bonetti A
J Clin Oncol 2000 Aug;18(16):2938-47. doi: 10.1200/JCO.2000.18.16.2938. PMID: 10944126

Prognosis

Xu L, Su X, He Z, Zhang C, Lu J, Zhang G, Sun Y, Du X, Chi P, Wang Z, Zhong M, Wu A, Zhu A, Li F, Xu J, Kang L, Suo J, Deng H, Ye Y, Ding K, Xu T, Zhang Z, Zheng M, Xiao Y; RELARC Study Group
Lancet Oncol 2021 Mar;22(3):391-401. Epub 2021 Feb 12 doi: 10.1016/S1470-2045(20)30685-9. PMID: 33587893
Kannuna H, Rubio CA, Silverio PC, Girardin M, Goossens N, Rubbia-Brandt L, Puppa G
Diagn Pathol 2015 Jul 9;10:92. doi: 10.1186/s13000-015-0305-1. PMID: 26156870Free PMC Article
Fuchs CS, Marshall J, Mitchell E, Wierzbicki R, Ganju V, Jeffery M, Schulz J, Richards D, Soufi-Mahjoubi R, Wang B, Barrueco J
J Clin Oncol 2007 Oct 20;25(30):4779-86. doi: 10.1200/JCO.2007.11.3357. PMID: 17947725
Nozue M, Isaka N, Maruyama T, Kawamoto T, Seino KI, Tanagichi H, Fukao K
Oncol Rep 2002 Jan-Feb;9(1):93-6. PMID: 11748463
Yamaguchi A, Ishida T, Nishimura G, Kumaki T, Katoh M, Kosaka T, Yonemura Y, Miyazaki I
Br J Cancer 1989 Sep;60(3):382-4. doi: 10.1038/bjc.1989.289. PMID: 2789946Free PMC Article

Clinical prediction guides

Wu P, Deng W, Yan L, Wang C, Lou Y, Wang C
Int J Colorectal Dis 2023 Feb 11;38(1):35. doi: 10.1007/s00384-023-04343-7. PMID: 36773067
Pistolesi S, Fanelli GN, Giudice F, Garbini F, Naccarato AG, Cosio S, Caretto M, Gadducci A
Anticancer Res 2023 Jan;43(1):53-58. doi: 10.21873/anticanres.16133. PMID: 36585201
Cats A, Jansen EPM, van Grieken NCT, Sikorska K, Lind P, Nordsmark M, Meershoek-Klein Kranenbarg E, Boot H, Trip AK, Swellengrebel HAM, van Laarhoven HWM, Putter H, van Sandick JW, van Berge Henegouwen MI, Hartgrink HH, van Tinteren H, van de Velde CJH, Verheij M; CRITICS investigators
Lancet Oncol 2018 May;19(5):616-628. Epub 2018 Apr 9 doi: 10.1016/S1470-2045(18)30132-3. PMID: 29650363
Kannuna H, Rubio CA, Silverio PC, Girardin M, Goossens N, Rubbia-Brandt L, Puppa G
Diagn Pathol 2015 Jul 9;10:92. doi: 10.1186/s13000-015-0305-1. PMID: 26156870Free PMC Article
Quirke P, Morris E
Histopathology 2007 Jan;50(1):103-12. doi: 10.1111/j.1365-2559.2006.02543.x. PMID: 17204025

Recent systematic reviews

Silva A, Cerqueira MC, Rosa B, Sobral C, Pinto-Ribeiro F, Costa MF, Baltazar F, Afonso J
Int J Mol Sci 2023 Mar 7;24(6) doi: 10.3390/ijms24065141. PMID: 36982217Free PMC Article
Lauricella S, Fabris S, Sylla P
Surg Endosc 2023 Jan;37(1):48-61. Epub 2022 Aug 3 doi: 10.1007/s00464-022-09462-w. PMID: 35920906
van Dorp M, Bousema JE, Torensma B, Dickhoff C, van den Broek FJC, Schreurs WH, Gonzalez M, Kazemier G, Heineman DJ
Eur J Surg Oncol 2022 Jan;48(1):253-260. Epub 2021 Oct 11 doi: 10.1016/j.ejso.2021.09.020. PMID: 34656390
Christensen MV, Høgdall CK, Jochumsen KM, Høgdall EVS
Int J Oncol 2018 Jan;52(1):5-18. Epub 2017 Nov 8 doi: 10.3892/ijo.2017.4197. PMID: 29115416
Kyrgiou M, Kalliala I, Markozannes G, Gunter MJ, Paraskevaidis E, Gabra H, Martin-Hirsch P, Tsilidis KK
BMJ 2017 Feb 28;356:j477. doi: 10.1136/bmj.j477. PMID: 28246088Free PMC Article

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