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Colon Carcinoma Metastatic in the Liver

MedGen UID:
234159
•Concept ID:
C1333085
•
Neoplastic Process
Synonym: Colon Carcinoma Metastatic to the Liver

Definition

A carcinoma that originates from the colonic wall and has spread to the liver. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColon Carcinoma Metastatic in the Liver

Professional guidelines

PubMed

Selective Internal Radiation Therapy in the Multidisciplinary Management of Liver Metastases From Colorectal Carcinoma.
Tchelebi L, Sharma NK
Semin Nucl Med 2019 May;49(3):182-188. Epub 2019 Feb 14 doi: 10.1053/j.semnuclmed.2019.01.002. PMID: 30954183
Practice Guideline for the Surveillance of Patients After Curative Treatment of Colon and Rectal Cancer.
Steele SR, Chang GJ, Hendren S, Weiser M, Irani J, Buie WD, Rafferty JF; Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons
Dis Colon Rectum 2015 Aug;58(8):713-25. doi: 10.1097/DCR.0000000000000410. PMID: 26163950
The role of capecitabine in the management of tumors of the digestive system.
Gennatas C, Michalaki V, Gennatas S
Rev Recent Clin Trials 2009 Jan;4(1):1-11. doi: 10.2174/157488709787047576. PMID: 19149758

Recent clinical studies

Etiology

(90)Y-microsphere radioembolization: The method, clinical evidence and perspective.
Spyridonidis T, Papathanasiou N, Spyridonidis J, Ntzoumani C, Spyropoulou D, Katsanos K, Apostolopoulos DJ
Hell J Nucl Med 2020 Sep-Dec;23(3):330-338. Epub 2020 Dec 14 doi: 10.1967/s002449912210. PMID: 33306761
Challenges in Reirradiation of Intrahepatic Tumors.
Owen D, Lukovic J, Hosni A, Crane CH, Hong TS, Dawson LA, Velec M, Lawrence TS
Semin Radiat Oncol 2020 Jul;30(3):242-252. doi: 10.1016/j.semradonc.2020.02.004. PMID: 32503790
Liver transplantation for colorectal liver metastases: What do we need to know?
Line PD, Ruffolo LI, Toso C, Dueland S, Nadalin S, Hernandez-Alejandro R
Int J Surg 2020 Oct;82S:87-92. Epub 2020 Apr 17 doi: 10.1016/j.ijsu.2020.03.079. PMID: 32305529
Scan? Cure? Sure!
Goldberg RM, Ryan DP
Oncologist 2011;16(2):254-6. doi: 10.1634/theoncologist.2011-0014. PMID: 21349952Free PMC Article
Carcinoid tumors.
Dawes L, Schulte WJ, Condon RE
Arch Surg 1984 Apr;119(4):375-8. doi: 10.1001/archsurg.1984.01390160011002. PMID: 6703893

Diagnosis

Gastrointestinal malignancy in cystic fibrosis.
Hough NE, Chapman SJ, Flight WG
Paediatr Respir Rev 2020 Sep;35:90-92. Epub 2020 Apr 9 doi: 10.1016/j.prrv.2020.03.002. PMID: 32505496
Patterns of metastasis in colon and rectal cancer.
Riihimäki M, Hemminki A, Sundquist J, Hemminki K
Sci Rep 2016 Jul 15;6:29765. doi: 10.1038/srep29765. PMID: 27416752Free PMC Article
Scan? Cure? Sure!
Goldberg RM, Ryan DP
Oncologist 2011;16(2):254-6. doi: 10.1634/theoncologist.2011-0014. PMID: 21349952Free PMC Article
Metastasis of colorectal carcinoma to the testes: clinical presentation and possible pathways.
Hatoum HA, Abi Saad GS, Otrock ZK, Barada KA, Shamseddine AI
Int J Clin Oncol 2011 Jun;16(3):203-9. Epub 2010 Nov 11 doi: 10.1007/s10147-010-0140-z. PMID: 21069550
Surgical treatment of colon cancer.
Rossi H, Rothenberger DA
Surg Oncol Clin N Am 2006 Jan;15(1):109-27, vii. doi: 10.1016/j.soc.2005.08.005. PMID: 16389153

Therapy

Gastrointestinal malignancy in cystic fibrosis.
Hough NE, Chapman SJ, Flight WG
Paediatr Respir Rev 2020 Sep;35:90-92. Epub 2020 Apr 9 doi: 10.1016/j.prrv.2020.03.002. PMID: 32505496
Selective Internal Radiation Therapy in the Multidisciplinary Management of Liver Metastases From Colorectal Carcinoma.
Tchelebi L, Sharma NK
Semin Nucl Med 2019 May;49(3):182-188. Epub 2019 Feb 14 doi: 10.1053/j.semnuclmed.2019.01.002. PMID: 30954183
Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer.
Bullman S, Pedamallu CS, Sicinska E, Clancy TE, Zhang X, Cai D, Neuberg D, Huang K, Guevara F, Nelson T, Chipashvili O, Hagan T, Walker M, Ramachandran A, Diosdado B, Serna G, Mulet N, Landolfi S, Ramon Y Cajal S, Fasani R, Aguirre AJ, Ng K, Élez E, Ogino S, Tabernero J, Fuchs CS, Hahn WC, Nuciforo P, Meyerson M
Science 2017 Dec 15;358(6369):1443-1448. Epub 2017 Nov 23 doi: 10.1126/science.aal5240. PMID: 29170280Free PMC Article
A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes.
Rosenberg SA, Spiess P, Lafreniere R
Science 1986 Sep 19;233(4770):1318-21. doi: 10.1126/science.3489291. PMID: 3489291
Infusion-embolization.
Wallace S, Charnsangavej C, Carrasco CH, Bechtel W
Cancer 1984 Dec 1;54(11 Suppl):2751-65. doi: 10.1002/1097-0142(19841201)54:2+<2751::aid-cncr2820541423>3.0.co;2-5. PMID: 6093984

Prognosis

Gastrointestinal malignancy in cystic fibrosis.
Hough NE, Chapman SJ, Flight WG
Paediatr Respir Rev 2020 Sep;35:90-92. Epub 2020 Apr 9 doi: 10.1016/j.prrv.2020.03.002. PMID: 32505496
Incidence, prognosis, and treatment options for patients with synchronous peritoneal carcinomatosis and liver metastases from colorectal origin.
Thomassen I, van Gestel YR, Lemmens VE, de Hingh IH
Dis Colon Rectum 2013 Dec;56(12):1373-80. doi: 10.1097/DCR.0b013e3182a62d9d. PMID: 24201391
Metastatic signet ring colon cancer in a Caribbean young adult and review of the literature.
Koczka CP, Goodman A
Eur J Gastroenterol Hepatol 2012 Jun;24(6):731-4. doi: 10.1097/MEG.0b013e328352819d. PMID: 22422005
Scan? Cure? Sure!
Goldberg RM, Ryan DP
Oncologist 2011;16(2):254-6. doi: 10.1634/theoncologist.2011-0014. PMID: 21349952Free PMC Article
Photodynamic therapy for cholangiocarcinoma.
Berr F
Semin Liver Dis 2004 May;24(2):177-87. doi: 10.1055/s-2004-828894. PMID: 15192790

Clinical prediction guides

Multi-omic analysis reveals metabolic pathways that characterize right-sided colon cancer liver metastasis.
Morris MT, Jain A, Sun B, Kurbatov V, Muca E, Zeng Z, Jin Y, Roper J, Lu J, Paty PB, Johnson CH, Khan SA
Cancer Lett 2023 Oct 10;574:216384. Epub 2023 Sep 14 doi: 10.1016/j.canlet.2023.216384. PMID: 37716465Free PMC Article
Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles.
Kakiuchi Y, Kuroda S, Kanaya N, Kumon K, Tsumura T, Hashimoto M, Yagi C, Sugimoto R, Hamada Y, Kikuchi S, Nishizaki M, Kagawa S, Tazawa H, Urata Y, Fujiwara T
Mol Ther 2021 Oct 6;29(10):2920-2930. Epub 2021 May 21 doi: 10.1016/j.ymthe.2021.05.015. PMID: 34023506Free PMC Article
Chemotherapy of metastatic colon cancer in France: A population-based study.
Mas L, Bachet JB, Jooste V, Lepage C, Bouvier AM
Dig Liver Dis 2021 Oct;53(10):1334-1342. Epub 2021 Apr 14 doi: 10.1016/j.dld.2021.03.019. PMID: 33865721
Robotic ALPPS.
Machado MAC, Surjan RC, Makdissi F
Ann Surg Oncol 2020 Apr;27(4):1174-1179. Epub 2019 Nov 4 doi: 10.1245/s10434-019-08027-x. PMID: 31686346
Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer.
Bullman S, Pedamallu CS, Sicinska E, Clancy TE, Zhang X, Cai D, Neuberg D, Huang K, Guevara F, Nelson T, Chipashvili O, Hagan T, Walker M, Ramachandran A, Diosdado B, Serna G, Mulet N, Landolfi S, Ramon Y Cajal S, Fasani R, Aguirre AJ, Ng K, Élez E, Ogino S, Tabernero J, Fuchs CS, Hahn WC, Nuciforo P, Meyerson M
Science 2017 Dec 15;358(6369):1443-1448. Epub 2017 Nov 23 doi: 10.1126/science.aal5240. PMID: 29170280Free PMC Article

Recent systematic reviews

Electrocoagulation for liver metastases.
Storman D, Swierz MJ, Riemsma RP, Wolff R, Mitus JW, Pedziwiatr M, Kleijnen J, Bala MM
Cochrane Database Syst Rev 2021 Jan 28;1(1):CD009497. doi: 10.1002/14651858.CD009497.pub3. PMID: 33507555Free PMC Article
Percutaneous ethanol injection for liver metastases.
Swierz MJ, Storman D, Riemsma RP, Wolff R, Mitus JW, Pedziwiatr M, Kleijnen J, Bala MM
Cochrane Database Syst Rev 2020 Feb 4;2(2):CD008717. doi: 10.1002/14651858.CD008717.pub3. PMID: 32017845Free PMC Article
Cryotherapy for liver metastases.
Bala MM, Riemsma RP, Wolff R, Pedziwiatr M, Mitus JW, Storman D, Swierz MJ, Kleijnen J
Cochrane Database Syst Rev 2019 Jul 10;7(7):CD009058. doi: 10.1002/14651858.CD009058.pub3. PMID: 31291464Free PMC Article
Timing of hepatectomy in resectable synchronous colorectal liver metastases (SCRLM): Simultaneous or delayed?
Yin Z, Liu C, Chen Y, Bai Y, Shang C, Yin R, Yin D, Wang J
Hepatology 2013 Jun;57(6):2346-57. doi: 10.1002/hep.26283. PMID: 23359206
Does the taking of biopsies affect the metastatic potential of tumours? A systematic review of reports on veterinary and human cases and animal models.
Klopfleisch R, Sperling C, Kershaw O, Gruber AD
Vet J 2011 Nov;190(2):e31-e42. Epub 2011 Jul 1 doi: 10.1016/j.tvjl.2011.04.010. PMID: 21723757

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