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Oral Cavity Adenocarcinoma

MedGen UID:
233792
•Concept ID:
C1335115
•
Neoplastic Process
Synonyms: Adenocarcinoma of Mouth; Adenocarcinoma of Oral Cavity; Adenocarcinoma of the Mouth; Adenocarcinoma of the Oral Cavity; Mouth Adenocarcinoma

Definition

An adenocarcinoma that arises from the oral cavity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOral Cavity Adenocarcinoma

Professional guidelines

PubMed

Current opinions on diagnosis and treatment of adenoid cystic carcinoma.
Fang Y, Peng Z, Wang Y, Gao K, Liu Y, Fan R, Zhang H, Xie Z, Jiang W
Oral Oncol 2022 Jul;130:105945. Epub 2022 Jun 2 doi: 10.1016/j.oraloncology.2022.105945. PMID: 35662026
The Evaluation and Management of Carcinoma of the Minor Salivary Glands.
Walvekar R, Phalke NP
Otolaryngol Clin North Am 2021 Jun;54(3):629-639. doi: 10.1016/j.otc.2021.02.011. PMID: 34024489
Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland.
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585

Recent clinical studies

Etiology

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands.
Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980Free PMC Article
Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis.
Cantù G
Acta Otorhinolaryngol Ital 2021 Jun;41(3):206-214. doi: 10.14639/0392-100X-N1379. PMID: 34264913Free PMC Article
Distant metastasis from oral cavity-correlation between histopathology results and primary site.
Uchiyama Y, Sasai T, Nakatani A, Shimamoto H, Tsujimoto T, Kreiborg S, Murakami S
Oral Radiol 2021 Apr;37(2):167-179. Epub 2020 May 28 doi: 10.1007/s11282-020-00440-3. PMID: 32468449
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study.
Fan X, Alekseyenko AV, Wu J, Peters BA, Jacobs EJ, Gapstur SM, Purdue MP, Abnet CC, Stolzenberg-Solomon R, Miller G, Ravel J, Hayes RB, Ahn J
Gut 2018 Jan;67(1):120-127. Epub 2016 Oct 14 doi: 10.1136/gutjnl-2016-312580. PMID: 27742762Free PMC Article

Diagnosis

Current opinions on diagnosis and treatment of adenoid cystic carcinoma.
Fang Y, Peng Z, Wang Y, Gao K, Liu Y, Fan R, Zhang H, Xie Z, Jiang W
Oral Oncol 2022 Jul;130:105945. Epub 2022 Jun 2 doi: 10.1016/j.oraloncology.2022.105945. PMID: 35662026
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands.
Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980Free PMC Article
Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study.
Fan X, Alekseyenko AV, Wu J, Peters BA, Jacobs EJ, Gapstur SM, Purdue MP, Abnet CC, Stolzenberg-Solomon R, Miller G, Ravel J, Hayes RB, Ahn J
Gut 2018 Jan;67(1):120-127. Epub 2016 Oct 14 doi: 10.1136/gutjnl-2016-312580. PMID: 27742762Free PMC Article
Salivary Gland Tumors: Current Concepts and Controversies.
Seethala RR
Surg Pathol Clin 2017 Mar;10(1):155-176. doi: 10.1016/j.path.2016.11.004. PMID: 28153132
Salivary glands.
Saunders JR Jr, Hirata RM, Jaques DA
Surg Clin North Am 1986 Feb;66(1):59-81. doi: 10.1016/s0039-6109(16)43829-6. PMID: 3003940

Therapy

Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets.
Ferrarotto R, Mitani Y, McGrail DJ, Li K, Karpinets TV, Bell D, Frank SJ, Song X, Kupferman ME, Liu B, Lee JJ, Glisson BS, Zhang J, Aster JC, Lin SY, Futreal PA, Heymach JV, El-Naggar AK
Clin Cancer Res 2021 Feb 1;27(3):852-864. Epub 2020 Nov 10 doi: 10.1158/1078-0432.CCR-20-1192. PMID: 33172898Free PMC Article
Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study.
Fan X, Alekseyenko AV, Wu J, Peters BA, Jacobs EJ, Gapstur SM, Purdue MP, Abnet CC, Stolzenberg-Solomon R, Miller G, Ravel J, Hayes RB, Ahn J
Gut 2018 Jan;67(1):120-127. Epub 2016 Oct 14 doi: 10.1136/gutjnl-2016-312580. PMID: 27742762Free PMC Article
Gastroesophageal Reflux Disease.
Kellerman R, Kintanar T
Prim Care 2017 Dec;44(4):561-573. Epub 2017 Oct 5 doi: 10.1016/j.pop.2017.07.001. PMID: 29132520
Pazopanib versus sunitinib in metastatic renal-cell carcinoma.
Motzer RJ, Hutson TE, Cella D, Reeves J, Hawkins R, Guo J, Nathan P, Staehler M, de Souza P, Merchan JR, Boleti E, Fife K, Jin J, Jones R, Uemura H, De Giorgi U, Harmenberg U, Wang J, Sternberg CN, Deen K, McCann L, Hackshaw MD, Crescenzo R, Pandite LN, Choueiri TK
N Engl J Med 2013 Aug 22;369(8):722-31. doi: 10.1056/NEJMoa1303989. PMID: 23964934
Tobacco smoking and cancer: a brief review of recent epidemiological evidence.
Sasco AJ, Secretan MB, Straif K
Lung Cancer 2004 Aug;45 Suppl 2:S3-9. doi: 10.1016/j.lungcan.2004.07.998. PMID: 15552776

Prognosis

Clinicopathological characteristics, treatment and prognosis of oral adenocarcinoma: a population-based study.
Wang Y, Wang S, Qu Y, Yang Y
Eur Arch Otorhinolaryngol 2023 Jul;280(7):3365-3374. Epub 2023 Mar 9 doi: 10.1007/s00405-023-07912-2. PMID: 36892615
Distant metastasis from oral cavity-correlation between histopathology results and primary site.
Uchiyama Y, Sasai T, Nakatani A, Shimamoto H, Tsujimoto T, Kreiborg S, Murakami S
Oral Radiol 2021 Apr;37(2):167-179. Epub 2020 May 28 doi: 10.1007/s11282-020-00440-3. PMID: 32468449
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Polymorphous adenocarcinoma of the salivary glands: reappraisal and update.
Vander Poorten V, Triantafyllou A, Skálová A, Stenman G, Bishop JA, Hauben E, Hunt JL, Hellquist H, Feys S, De Bree R, Mäkitie AA, Quer M, Strojan P, Guntinas-Lichius O, Rinaldo A, Ferlito A
Eur Arch Otorhinolaryngol 2018 Jul;275(7):1681-1695. Epub 2018 May 14 doi: 10.1007/s00405-018-4985-5. PMID: 29761209
Salivary Gland Tumors: Current Concepts and Controversies.
Seethala RR
Surg Pathol Clin 2017 Mar;10(1):155-176. doi: 10.1016/j.path.2016.11.004. PMID: 28153132

Clinical prediction guides

Characterization of Lung and Oral Microbiomes in Lung Cancer Patients Using Culturomics and 16S rRNA Gene Sequencing.
Sun Y, Liu Y, Li J, Tan Y, An T, Zhuo M, Pan Z, Ma M, Jia B, Zhang H, Wang Z, Yang R, Bi Y
Microbiol Spectr 2023 Jun 15;11(3):e0031423. Epub 2023 Apr 24 doi: 10.1128/spectrum.00314-23. PMID: 37092999Free PMC Article
Oral Cyanobacteria and Hepatocellular Carcinoma.
Hernandez BY, Zhu X, Risch HA, Lu L, Ma X, Irwin ML, Lim JK, Taddei TH, Pawlish KS, Stroup AM, Brown R, Wang Z, Wong LL, Yu H
Cancer Epidemiol Biomarkers Prev 2022 Jan;31(1):221-229. Epub 2021 Oct 25 doi: 10.1158/1055-9965.EPI-21-0804. PMID: 34697061Free PMC Article
Periodontal disease-related nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: An emerging concept of oral-liver axis.
Kuraji R, Sekino S, Kapila Y, Numabe Y
Periodontol 2000 2021 Oct;87(1):204-240. doi: 10.1111/prd.12387. PMID: 34463983Free PMC Article
Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets.
Ferrarotto R, Mitani Y, McGrail DJ, Li K, Karpinets TV, Bell D, Frank SJ, Song X, Kupferman ME, Liu B, Lee JJ, Glisson BS, Zhang J, Aster JC, Lin SY, Futreal PA, Heymach JV, El-Naggar AK
Clin Cancer Res 2021 Feb 1;27(3):852-864. Epub 2020 Nov 10 doi: 10.1158/1078-0432.CCR-20-1192. PMID: 33172898Free PMC Article
Acanthosis nigricans.
Sedano HO, Gorlin RJ
Oral Surg Oral Med Oral Pathol 1987 Apr;63(4):462-7. doi: 10.1016/0030-4220(87)90259-3. PMID: 3554094

Recent systematic reviews

Gastric adenocarcinoma and periodontal disease: A systematic review and meta-analysis.
Aguiar FJN, Menezes FDS, Fagundes MA, Fernandes GA, Alves FA, Filho JG, Curado MP
Clinics (Sao Paulo) 2024;79:100321. Epub 2024 Jan 31 doi: 10.1016/j.clinsp.2023.100321. PMID: 38301538Free PMC Article
The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis.
Wu Y, Hong Q, Lu F, Zhang Z, Li J, Nie Z, He B
Mol Diagn Ther 2023 May;27(3):283-301. Epub 2023 Mar 20 doi: 10.1007/s40291-023-00641-6. PMID: 36939982
Clinicopathological analysis of oral and maxillofacial acinic cell carcinoma: A systematic review.
Kirschnick LB, Silveira FM, Schuch LF, Fonseca FP, Martins MAT, Lopes MA, Santos-Silva AR, Carrard VC, Dos Santos JN, Vargas PA, Wagner VP, Martins MD
J Oral Pathol Med 2021 Sep;50(8):741-749. Epub 2021 Feb 18 doi: 10.1111/jop.13159. PMID: 33455041
A systematic review of secretory carcinoma of the salivary gland: where are we?
Alves LDB, de Melo AC, Farinha TA, de Lima Araujo LH, Thiago LS, Dias FL, Antunes HS, Amaral Eisenberg AL, Santos Thuler LC, Cohen Goldemberg D
Oral Surg Oral Med Oral Pathol Oral Radiol 2021 Oct;132(4):e143-e152. Epub 2020 May 31 doi: 10.1016/j.oooo.2020.04.007. PMID: 32493686
Distant metastasis from oral cavity-correlation between histopathology results and primary site.
Uchiyama Y, Sasai T, Nakatani A, Shimamoto H, Tsujimoto T, Kreiborg S, Murakami S
Oral Radiol 2021 Apr;37(2):167-179. Epub 2020 May 28 doi: 10.1007/s11282-020-00440-3. PMID: 32468449

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