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Colorectal Low Grade Intraepithelial Neoplasia

MedGen UID:
232383
•Concept ID:
C1333115
•
Neoplastic Process
Synonyms: Colorectal Low-Grade Dysplasia; Large Intestinal Low Grade Dysplasia; Large Intestinal Low Grade Intraepithelial Neoplasia

Definition

A precancerous neoplastic process that affects the colon or rectum. It is characterized by mild epithelial dysplasia and mild architectural alterations of the mucosal epithelium. There is no evidence of invasion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal Low Grade Intraepithelial Neoplasia

Professional guidelines

PubMed

Systematic review of guidelines for the assessment and management of high-grade anal intraepithelial neoplasia (AIN II/III).
Alam NN, White DA, Narang SK, Daniels IR, Smart NJ
Colorectal Dis 2016 Feb;18(2):135-46. doi: 10.1111/codi.13215. PMID: 26559167
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD
Gastroenterology 2013 Sep;145(3):521-36. Epub 2013 Jul 1 doi: 10.1053/j.gastro.2013.06.052. PMID: 23827861Free PMC Article
Atypical cribriform lesions of the prostate: clinical significance, differential diagnosis and current concept of intraductal carcinoma of the prostate.
Shah RB, Zhou M
Adv Anat Pathol 2012 Jul;19(4):270-8. doi: 10.1097/PAP.0b013e31825c6c0e. PMID: 22692290

Recent clinical studies

Etiology

Potential Factors Predicting Histopathologically Upgrade Discrepancies between Endoscopic Forceps Biopsy of the Colorectal Low-Grade Intraepithelial Neoplasia and Endoscopic Resection Specimens.
Hong J, Wang Y, Deng J, Qi M, Zuo W, Hao Y, Wang A, Tu Y, Xu S, Zhou X, Zhou X, Li G, Zhu L, Shu X, Zhu Y, Lv N, Chen Y
Biomed Res Int 2022;2022:1915458. Epub 2022 Jun 6 doi: 10.1155/2022/1915458. PMID: 35707387Free PMC Article

Diagnosis

Potential Factors Predicting Histopathologically Upgrade Discrepancies between Endoscopic Forceps Biopsy of the Colorectal Low-Grade Intraepithelial Neoplasia and Endoscopic Resection Specimens.
Hong J, Wang Y, Deng J, Qi M, Zuo W, Hao Y, Wang A, Tu Y, Xu S, Zhou X, Zhou X, Li G, Zhu L, Shu X, Zhu Y, Lv N, Chen Y
Biomed Res Int 2022;2022:1915458. Epub 2022 Jun 6 doi: 10.1155/2022/1915458. PMID: 35707387Free PMC Article

Prognosis

Potential Factors Predicting Histopathologically Upgrade Discrepancies between Endoscopic Forceps Biopsy of the Colorectal Low-Grade Intraepithelial Neoplasia and Endoscopic Resection Specimens.
Hong J, Wang Y, Deng J, Qi M, Zuo W, Hao Y, Wang A, Tu Y, Xu S, Zhou X, Zhou X, Li G, Zhu L, Shu X, Zhu Y, Lv N, Chen Y
Biomed Res Int 2022;2022:1915458. Epub 2022 Jun 6 doi: 10.1155/2022/1915458. PMID: 35707387Free PMC Article

Clinical prediction guides

Potential Factors Predicting Histopathologically Upgrade Discrepancies between Endoscopic Forceps Biopsy of the Colorectal Low-Grade Intraepithelial Neoplasia and Endoscopic Resection Specimens.
Hong J, Wang Y, Deng J, Qi M, Zuo W, Hao Y, Wang A, Tu Y, Xu S, Zhou X, Zhou X, Li G, Zhu L, Shu X, Zhu Y, Lv N, Chen Y
Biomed Res Int 2022;2022:1915458. Epub 2022 Jun 6 doi: 10.1155/2022/1915458. PMID: 35707387Free PMC Article

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