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Cerebellar astrocytoma

MedGen UID:
196631
Concept ID:
C0740480
Neoplastic Process
Synonyms: astrocytoma (excluding glioblastoma) of cerebellum; Astrocytoma of Cerebellum; astrocytoma of cerebellum; Astrocytoma of the Cerebellum; astrocytoma of the cerebellum; Astrocytoma, Cerebellar; astrocytoma, cerebellar; Cerebellar Astrocytoma; cerebellar astrocytoma; cerebellum astrocytoma; cerebellum astrocytoma (excluding glioblastoma)
 
Monarch Initiative: MONDO:0003165

Definition

Benign and malignant neoplasms of the cerebellum that arise from astrocytes. During childhood the majority are benign pilocytic astrocytomas. In adults both benign and relatively higher grade forms may occur. The most common presenting symptoms are headache, nausea, vomiting, ataxia of gait or limb, paresis, diplopia, and dizziness. Objective signs include weakness, long tract signs, dysmetria, gait ataxia, papilledema, and nystagmus. Surgical resection is often curative. [from NCI]

Professional guidelines

PubMed

Due-Tønnessen BJ, Lundar T, Egge A, Scheie D
J Neurosurg Pediatr 2013 Mar;11(3):245-9. Epub 2012 Dec 14 doi: 10.3171/2012.11.PEDS12265. PMID: 23240848
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Larson DA, Wara WM, Edwards MS
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Recent clinical studies

Etiology

Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Wang X, Luo P, Hanazawa H, Liu J, Li L, Wang M, Jing Z
Eur J Dermatol 2018 Apr 1;28(2):254-255. doi: 10.1684/ejd.2018.3218. PMID: 29619995
Keezer MR, Del Maestro R
Can J Neurol Sci 2009 May;36(3):303-10. doi: 10.1017/s0317167100007022. PMID: 19534329
Rashidi M, DaSilva VR, Minagar A, Rutka JT
Curr Neurol Neurosci Rep 2003 May;3(3):200-5. doi: 10.1007/s11910-003-0079-9. PMID: 12691624
Hirano A, Hirano M
Childs Nerv Syst 1988 Dec;4(6):325-33. doi: 10.1007/BF00270605. PMID: 3073001

Diagnosis

Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Brandão LA, Young Poussaint T
Neuroimaging Clin N Am 2017 Feb;27(1):1-37. doi: 10.1016/j.nic.2016.08.001. PMID: 27889018
Rasalkar DD, Chu WC, Paunipagar BK, Cheng FW, Li CK
Postgrad Med J 2013 Jan;89(1047):39-46. Epub 2012 Sep 12 doi: 10.1136/postgradmedj-2011-130075. PMID: 22977284
Rashidi M, DaSilva VR, Minagar A, Rutka JT
Curr Neurol Neurosci Rep 2003 May;3(3):200-5. doi: 10.1007/s11910-003-0079-9. PMID: 12691624
Hirano A, Hirano M
Childs Nerv Syst 1988 Dec;4(6):325-33. doi: 10.1007/BF00270605. PMID: 3073001

Therapy

Martínez-Lage JF, Almagro MJ, Serrano C, Mena L
Childs Nerv Syst 2011 Jan;27(1):163-5. Epub 2010 Jun 24 doi: 10.1007/s00381-010-1213-z. PMID: 20574740
Keezer MR, Del Maestro R
Can J Neurol Sci 2009 May;36(3):303-10. doi: 10.1017/s0317167100007022. PMID: 19534329
Furuta T, Sugiu K, Tamiya T, Matsumoto K, Ohmoto T
Clin Neurol Neurosurg 1998 Mar;100(1):56-9. doi: 10.1016/s0303-8467(97)00122-4. PMID: 9637208
Babu R, Huang PP, Epstein F, Budzilovich GN
J Neurooncol 1993 Jul;17(1):37-42. doi: 10.1007/BF01054272. PMID: 8120570
Raney RB Jr, Lawrence W Jr, Maurer HM, Lindberg RD, Newton WA Jr, Ragab AH, Tefft M, Foulkes MA
Cancer 1983 Jun 15;51(12):2356-61. doi: 10.1002/1097-0142(19830615)51:12<2356::aid-cncr2820511232>3.0.co;2-l. PMID: 6342748

Prognosis

Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Wang X, Luo P, Hanazawa H, Liu J, Li L, Wang M, Jing Z
Eur J Dermatol 2018 Apr 1;28(2):254-255. doi: 10.1684/ejd.2018.3218. PMID: 29619995
Rasalkar DD, Chu WC, Paunipagar BK, Cheng FW, Li CK
Postgrad Med J 2013 Jan;89(1047):39-46. Epub 2012 Sep 12 doi: 10.1136/postgradmedj-2011-130075. PMID: 22977284
Rashidi M, DaSilva VR, Minagar A, Rutka JT
Curr Neurol Neurosci Rep 2003 May;3(3):200-5. doi: 10.1007/s11910-003-0079-9. PMID: 12691624
Schwartz AM, Ghatak NR
Cancer 1990 Jan 15;65(2):333-6. doi: 10.1002/1097-0142(19900115)65:2<333::aid-cncr2820650225>3.0.co;2-3. PMID: 2403835

Clinical prediction guides

Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Steinbok P, Mangat JS, Kerr JM, Sargent M, Suryaningtyas W, Singhal A, Cochrane D
Childs Nerv Syst 2013 Aug;29(8):1269-75. Epub 2013 May 29 doi: 10.1007/s00381-013-2171-z. PMID: 23715810
Schwartz AM, Ghatak NR
Cancer 1990 Jan 15;65(2):333-6. doi: 10.1002/1097-0142(19900115)65:2<333::aid-cncr2820650225>3.0.co;2-3. PMID: 2403835
Hirano A, Hirano M
Childs Nerv Syst 1988 Dec;4(6):325-33. doi: 10.1007/BF00270605. PMID: 3073001
Rubinstein LJ, Herman MM, Hanbery JW
Cancer 1974 Mar;33(3):675-90. doi: 10.1002/1097-0142(197403)33:3<675::aid-cncr2820330312>3.0.co;2-e. PMID: 4815572

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