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Locally Advanced HER2-Positive Breast Carcinoma

MedGen UID:
1793709
Concept ID:
C5557268
Neoplastic Process
Synonym: Locally Advanced HER2 Positive Breast Carcinoma

Definition

HER2-positive breast carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced HER2-Positive Breast Carcinoma

Professional guidelines

PubMed

Karpel HC, Slomovitz B, Coleman RL, Pothuri B
Curr Opin Obstet Gynecol 2023 Jun 1;35(3):270-278. Epub 2023 Mar 20 doi: 10.1097/GCO.0000000000000855. PMID: 36943683
Galanti D, Inno A, La Vecchia M, Borsellino N, Incorvaia L, Russo A, Gori S
Crit Rev Oncol Hematol 2021 May;161:103329. Epub 2021 Apr 20 doi: 10.1016/j.critrevonc.2021.103329. PMID: 33862249
Goutsouliak K, Veeraraghavan J, Sethunath V, De Angelis C, Osborne CK, Rimawi MF, Schiff R
Nat Rev Clin Oncol 2020 Apr;17(4):233-250. Epub 2019 Dec 13 doi: 10.1038/s41571-019-0299-9. PMID: 31836877Free PMC Article

Recent clinical studies

Etiology

Hong R, Xu B
Cancer Commun (Lond) 2022 Oct;42(10):913-936. Epub 2022 Sep 8 doi: 10.1002/cac2.12358. PMID: 36074908Free PMC Article
Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Tan AR, Im SA, Mattar A, Colomer R, Stroyakovskii D, Nowecki Z, De Laurentiis M, Pierga JY, Jung KH, Schem C, Hogea A, Badovinac Crnjevic T, Heeson S, Shivhare M, Kirschbrown WP, Restuccia E, Jackisch C; FeDeriCa study group
Lancet Oncol 2021 Jan;22(1):85-97. Epub 2020 Dec 21 doi: 10.1016/S1470-2045(20)30536-2. PMID: 33357420
Gianni L, Pienkowski T, Im YH, Tseng LM, Liu MC, Lluch A, Starosławska E, de la Haba-Rodriguez J, Im SA, Pedrini JL, Poirier B, Morandi P, Semiglazov V, Srimuninnimit V, Bianchi GV, Magazzù D, McNally V, Douthwaite H, Ross G, Valagussa P
Lancet Oncol 2016 Jun;17(6):791-800. Epub 2016 May 11 doi: 10.1016/S1470-2045(16)00163-7. PMID: 27179402
Gianni L, Pienkowski T, Im YH, Roman L, Tseng LM, Liu MC, Lluch A, Staroslawska E, de la Haba-Rodriguez J, Im SA, Pedrini JL, Poirier B, Morandi P, Semiglazov V, Srimuninnimit V, Bianchi G, Szado T, Ratnayake J, Ross G, Valagussa P
Lancet Oncol 2012 Jan;13(1):25-32. Epub 2011 Dec 6 doi: 10.1016/S1470-2045(11)70336-9. PMID: 22153890

Diagnosis

Cantini L, Trapani D, Guidi L, Boscolo Bielo L, Scafetta R, Koziej M, Vidal L, Saini KS, Curigliano G
Cancer Treat Rev 2024 Feb;123:102669. Epub 2023 Dec 10 doi: 10.1016/j.ctrv.2023.102669. PMID: 38141462
Mills MN, King W, Soyano A, Pina Y, Czerniecki BJ, Forsyth PA, Soliman H, Han HS, Ahmed KA
J Neurooncol 2022 Apr;157(2):249-269. Epub 2022 Mar 4 doi: 10.1007/s11060-022-03977-x. PMID: 35244835
Zimmer AS, Van Swearingen AED, Anders CK
Cancer Rep (Hoboken) 2022 Apr;5(4):e1274. Epub 2020 Sep 3 doi: 10.1002/cnr2.1274. PMID: 32881421Free PMC Article
Soffietti R, Ahluwalia M, Lin N, Rudà R
Nat Rev Neurol 2020 Oct;16(10):557-574. Epub 2020 Sep 1 doi: 10.1038/s41582-020-0391-x. PMID: 32873927
Zhang B, Hurvitz S
Clin Adv Hematol Oncol 2016 Jul;14(7):520-30. PMID: 27379947

Therapy

Cantini L, Trapani D, Guidi L, Boscolo Bielo L, Scafetta R, Koziej M, Vidal L, Saini KS, Curigliano G
Cancer Treat Rev 2024 Feb;123:102669. Epub 2023 Dec 10 doi: 10.1016/j.ctrv.2023.102669. PMID: 38141462
Hong R, Xu B
Cancer Commun (Lond) 2022 Oct;42(10):913-936. Epub 2022 Sep 8 doi: 10.1002/cac2.12358. PMID: 36074908Free PMC Article
Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Tan AR, Im SA, Mattar A, Colomer R, Stroyakovskii D, Nowecki Z, De Laurentiis M, Pierga JY, Jung KH, Schem C, Hogea A, Badovinac Crnjevic T, Heeson S, Shivhare M, Kirschbrown WP, Restuccia E, Jackisch C; FeDeriCa study group
Lancet Oncol 2021 Jan;22(1):85-97. Epub 2020 Dec 21 doi: 10.1016/S1470-2045(20)30536-2. PMID: 33357420
Schneeweiss A, Chia S, Hickish T, Harvey V, Eniu A, Hegg R, Tausch C, Seo JH, Tsai YF, Ratnayake J, McNally V, Ross G, Cortés J
Ann Oncol 2013 Sep;24(9):2278-84. Epub 2013 May 22 doi: 10.1093/annonc/mdt182. PMID: 23704196

Prognosis

Karpel HC, Slomovitz B, Coleman RL, Pothuri B
Curr Opin Obstet Gynecol 2023 Jun 1;35(3):270-278. Epub 2023 Mar 20 doi: 10.1097/GCO.0000000000000855. PMID: 36943683
Barchiesi G, Mazzotta M, Krasniqi E, Pizzuti L, Marinelli D, Capomolla E, Sergi D, Amodio A, Natoli C, Gamucci T, Vizza E, Marchetti P, Botti C, Sanguineti G, Ciliberto G, Barba M, Vici P
Int J Mol Sci 2020 May 16;21(10) doi: 10.3390/ijms21103528. PMID: 32429381Free PMC Article
Diéras V, Miles D, Verma S, Pegram M, Welslau M, Baselga J, Krop IE, Blackwell K, Hoersch S, Xu J, Green M, Gianni L
Lancet Oncol 2017 Jun;18(6):732-742. Epub 2017 May 16 doi: 10.1016/S1470-2045(17)30312-1. PMID: 28526536Free PMC Article
Gianni L, Pienkowski T, Im YH, Tseng LM, Liu MC, Lluch A, Starosławska E, de la Haba-Rodriguez J, Im SA, Pedrini JL, Poirier B, Morandi P, Semiglazov V, Srimuninnimit V, Bianchi GV, Magazzù D, McNally V, Douthwaite H, Ross G, Valagussa P
Lancet Oncol 2016 Jun;17(6):791-800. Epub 2016 May 11 doi: 10.1016/S1470-2045(16)00163-7. PMID: 27179402
Bartsch R, Ziebermayr R, Zielinski CC, Steger GG
Wien Med Wochenschr 2010 Apr;160(7-8):174-81. doi: 10.1007/s10354-010-0773-6. PMID: 20473728

Clinical prediction guides

Arpino G, de la Haba Rodríguez J, Ferrero JM, De Placido S, Osborne CK, Klingbiel D, Revelant V, Wohlfarth C, Poppe R, Rimawi MF; PERTAIN Study Group
Clin Cancer Res 2023 Apr 14;29(8):1468-1476. doi: 10.1158/1078-0432.CCR-22-1092. PMID: 36716289Free PMC Article
Barchiesi G, Mazzotta M, Krasniqi E, Pizzuti L, Marinelli D, Capomolla E, Sergi D, Amodio A, Natoli C, Gamucci T, Vizza E, Marchetti P, Botti C, Sanguineti G, Ciliberto G, Barba M, Vici P
Int J Mol Sci 2020 May 16;21(10) doi: 10.3390/ijms21103528. PMID: 32429381Free PMC Article
Tolaney SM, Wardley AM, Zambelli S, Hilton JF, Troso-Sandoval TA, Ricci F, Im SA, Kim SB, Johnston SR, Chan A, Goel S, Catron K, Chapman SC, Price GL, Yang Z, Gainford MC, André F
Lancet Oncol 2020 Jun;21(6):763-775. Epub 2020 Apr 27 doi: 10.1016/S1470-2045(20)30112-1. PMID: 32353342
Banerji U, van Herpen CML, Saura C, Thistlethwaite F, Lord S, Moreno V, Macpherson IR, Boni V, Rolfo C, de Vries EGE, Rottey S, Geenen J, Eskens F, Gil-Martin M, Mommers EC, Koper NP, Aftimos P
Lancet Oncol 2019 Aug;20(8):1124-1135. Epub 2019 Jun 27 doi: 10.1016/S1470-2045(19)30328-6. PMID: 31257177
Wu J, Cao G, Sun X, Lee J, Rubin DL, Napel S, Kurian AW, Daniel BL, Li R
Radiology 2018 Jul;288(1):26-35. Epub 2018 May 1 doi: 10.1148/radiol.2018172462. PMID: 29714680Free PMC Article

Recent systematic reviews

Kang Z, Jin Y, Yu H, Li S, Qi Y
BMC Cancer 2024 Jun 8;24(1):708. doi: 10.1186/s12885-024-12478-1. PMID: 38851684Free PMC Article
Ciapponi A, Bardach A, Colaci C, Rodríguez Cairoli F, Argento F, Korbenfeld E, García Martí S
Rev Peru Med Exp Salud Publica 2024 May 27;41(1):7-18. doi: 10.17843/rpmesp.2024.411.13351. PMID: 38808848Free PMC Article
Yeh Y, Chen C, Ko Y
J Cancer Res Ther 2022 Jul-Sep;18(4):1061-1072. doi: 10.4103/jcrt.jcrt_1095_21. PMID: 36149162
Ramakrishna N, Anders CK, Lin NU, Morikawa A, Temin S, Chandarlapaty S, Crews JR, Davidson NE, Franzoi MAB, Kirshner JJ, Krop IE, Patt DA, Perlmutter J, Giordano SH
J Clin Oncol 2022 Aug 10;40(23):2636-2655. Epub 2022 May 31 doi: 10.1200/JCO.22.00520. PMID: 35640075
Taylor AM, Chan DLH, Tio M, Patil SM, Traina TA, Robson ME, Khasraw M
Cochrane Database Syst Rev 2021 Apr 22;4(4):CD011395. doi: 10.1002/14651858.CD011395.pub2. PMID: 33886122Free PMC Article

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