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Glomerular basement membrane electron dense deposits

MedGen UID:
1781767
Concept ID:
C5539647
Finding
HPO: HP:0033499

Definition

Electron-dense deposits in the lamina densa with a ribbon or a sausage structure. [from HPO]

Recent clinical studies

Etiology

Liang D, Liang S, Xu F, Zhang M, Li X, Tu Y, Liu Z, Zeng C
J Clin Pathol 2019 Jan;72(1):31-37. Epub 2018 Oct 12 doi: 10.1136/jclinpath-2018-205278. PMID: 30315136
Tomino Y
Contrib Nephrol 2013;181:65-74. Epub 2013 May 8 doi: 10.1159/000348457. PMID: 23689568
Yong JL, Killingsworth MC, Spicer ST, Wu XJ
Int J Clin Exp Pathol 2009 Nov 20;3(2):210-6. PMID: 20126589Free PMC Article
D'Amico G, Ferrario F
J Am Soc Nephrol 1992 Apr;2(10 Suppl):S159-66. doi: 10.1681/ASN.V210s159. PMID: 1534701
Korbet SM, Schwartz MM, Rosenberg BF, Sibley RK, Lewis EJ
Medicine (Baltimore) 1985 Jul;64(4):228-43. doi: 10.1097/00005792-198507000-00004. PMID: 4010500

Diagnosis

Yu SM, Deoliveira M, Chung M, Lafayette R
Adv Kidney Dis Health 2024 May;31(3):216-222. doi: 10.1053/j.akdh.2024.03.005. PMID: 39004461Free PMC Article
Ahmad SB, Santoriello D, Canetta P, Bomback AS, D'Agati VD, Markowitz G, Ahn W, Radhakrishnan J, Appel GB
Am J Kidney Dis 2021 Aug;78(2):219-225.e1. Epub 2021 Jan 7 doi: 10.1053/j.ajkd.2020.11.023. PMID: 33421452
Licht C, Fremeaux-Bacchi V
Thromb Haemost 2009 Feb;101(2):271-8. PMID: 19190809
Korbet SM, Schwartz MM, Rosenberg BF, Sibley RK, Lewis EJ
Medicine (Baltimore) 1985 Jul;64(4):228-43. doi: 10.1097/00005792-198507000-00004. PMID: 4010500
Tubbs RR, Gephardt GN, McMahon JT, Hall PM, Valenzuela R, Vidt DG
Am J Med 1981 Aug;71(2):263-9. doi: 10.1016/0002-9343(81)90127-3. PMID: 6789678

Therapy

Ahmad SB, Santoriello D, Canetta P, Bomback AS, D'Agati VD, Markowitz G, Ahn W, Radhakrishnan J, Appel GB
Am J Kidney Dis 2021 Aug;78(2):219-225.e1. Epub 2021 Jan 7 doi: 10.1053/j.ajkd.2020.11.023. PMID: 33421452
Hirose O, Itabashi M, Takei T, Honda K, Nitta K
Clin Exp Nephrol 2017 Aug;21(4):643-650. Epub 2016 Nov 9 doi: 10.1007/s10157-016-1341-1. PMID: 27830351
Hiramatsu R, Ubara Y, Sawa N, Hasegawa E, Kawada M, Imafuku A, Sumida K, Mise K, Yamanouchi M, Ueno T, Sekine A, Hayami N, Suwabe T, Hoshino J, Takaichi K, Ohashi K, Fujii T, Wake A, Taniguchi S
Hum Pathol 2016 Apr;50:187-94. Epub 2015 Dec 29 doi: 10.1016/j.humpath.2015.12.005. PMID: 26997455
Kuroda N, Nao T, Fukuhara H, Karashima T, Inoue K, Taniguchi Y, Takeuchi M, Zen Y, Sato Y, Notohara K, Yoshino T
Int J Clin Exp Pathol 2014;7(9):6379-85. Epub 2014 Aug 15 PMID: 25337295Free PMC Article
Korbet SM, Schwartz MM, Rosenberg BF, Sibley RK, Lewis EJ
Medicine (Baltimore) 1985 Jul;64(4):228-43. doi: 10.1097/00005792-198507000-00004. PMID: 4010500

Prognosis

Ahmad SB, Santoriello D, Canetta P, Bomback AS, D'Agati VD, Markowitz G, Ahn W, Radhakrishnan J, Appel GB
Am J Kidney Dis 2021 Aug;78(2):219-225.e1. Epub 2021 Jan 7 doi: 10.1053/j.ajkd.2020.11.023. PMID: 33421452
Yong JL, Killingsworth MC, Spicer ST, Wu XJ
Int J Clin Exp Pathol 2009 Nov 20;3(2):210-6. PMID: 20126589Free PMC Article
Gaber LW, Spargo BH, Lindheimer MD
Baillieres Clin Obstet Gynaecol 1994 Jun;8(2):443-68. doi: 10.1016/s0950-3552(05)80330-x. PMID: 7924017
Yoshikawa N, Yoshiara S, Yoshiya K, Matsuo T, Okada S
J Pathol 1986 Oct;150(2):119-26. doi: 10.1002/path.1711500206. PMID: 3794864
Korbet SM, Schwartz MM, Rosenberg BF, Sibley RK, Lewis EJ
Medicine (Baltimore) 1985 Jul;64(4):228-43. doi: 10.1097/00005792-198507000-00004. PMID: 4010500

Clinical prediction guides

Kuroda N, Nao T, Fukuhara H, Karashima T, Inoue K, Taniguchi Y, Takeuchi M, Zen Y, Sato Y, Notohara K, Yoshino T
Int J Clin Exp Pathol 2014;7(9):6379-85. Epub 2014 Aug 15 PMID: 25337295Free PMC Article
Tomino Y
Contrib Nephrol 2013;181:65-74. Epub 2013 May 8 doi: 10.1159/000348457. PMID: 23689568
Gaber LW, Spargo BH, Lindheimer MD
Baillieres Clin Obstet Gynaecol 1994 Jun;8(2):443-68. doi: 10.1016/s0950-3552(05)80330-x. PMID: 7924017
Gaber LW, Spargo BH, Lindheimer MD
Baillieres Clin Obstet Gynaecol 1987 Dec;1(4):971-95. doi: 10.1016/s0950-3552(87)80045-7. PMID: 3330496
Yoshikawa N, Yoshiara S, Yoshiya K, Matsuo T, Okada S
J Pathol 1986 Oct;150(2):119-26. doi: 10.1002/path.1711500206. PMID: 3794864

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