U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Shortened sleep phase

MedGen UID:
1774915
•Concept ID:
C5421580
•
Finding
Synonym: Shortened sleep cycle
 
HPO: HP:0033063

Definition

A tendency to sleep fewer hours than usual while feeling well-rested. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVShortened sleep phase

Conditions with this feature

SHORT SLEEP, FAMILIAL NATURAL, 2
MedGen UID:
1684839
•Concept ID:
C5231420
•
Disease or Syndrome
Individuals with familial natural short sleep-2 (FNSS2) have a sleep requirement of 4 to 6 hours per night (Shi et al., 2019). For a discussion of genetic heterogeneity of FNSS, see FNSS1 (612975).
See: Condition Record
SHORT SLEEP, FAMILIAL NATURAL, 2

Professional guidelines

PubMed

Brain glucose metabolism in Lewy body dementia: implications for diagnostic criteria.
Caminiti SP, Sala A, Iaccarino L, Beretta L, Pilotto A, Gianolli L, Iannaccone S, Magnani G, Padovani A, Ferini-Strambi L, Perani D
Alzheimers Res Ther 2019 Feb 23;11(1):20. doi: 10.1186/s13195-019-0473-4. PMID: 30797240Free PMC Article
Progressive retinal ganglion cell loss in primary open-angle glaucoma is associated with temperature circadian rhythm phase delay and compromised sleep.
Gubin DG, Malishevskaya ТN, Astakhov YS, Astakhov SY, Cornelissen G, Kuznetsov VA, Weinert D
Chronobiol Int 2019 Apr;36(4):564-577. Epub 2019 Jan 21 doi: 10.1080/07420528.2019.1566741. PMID: 30663431
Risk constellations prior to the development of bipolar disorders: rationale of a new risk assessment tool.
Leopold K, Ritter P, Correll CU, Marx C, Özgürdal S, Juckel G, Bauer M, Pfennig A
J Affect Disord 2012 Feb;136(3):1000-10. Epub 2011 Jul 30 doi: 10.1016/j.jad.2011.06.043. PMID: 21802741

Recent clinical studies

Etiology

Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3.
Bedawi EO, Stavroulias D, Hedley E, Blyth KG, Kirk A, De Fonseka D, Edwards JG, Internullo E, Corcoran JP, Marchbank A, Panchal R, Caruana E, Kadwani O, Okiror L, Saba T, Purohit M, Mercer RM, Taberham R, Kanellakis N, Condliffe AM, Lewis LG, Addala DN, Asciak R, Banka R, George V, Hassan M, McCracken D, Sundaralingam A, Wrightson JM, Dobson M, West A, Barnes G, Harvey J, Slade M, Chester-Jones M, Dutton S, Miller RF, Maskell NA, Belcher E, Rahman NM
Am J Respir Crit Care Med 2023 Dec 15;208(12):1305-1315. doi: 10.1164/rccm.202305-0854OC. PMID: 37820359Free PMC Article
Delayed sleep-onset and biological age: late sleep-onset is associated with shorter telomere length.
Wynchank D, Bijlenga D, Penninx BW, Lamers F, Beekman AT, Kooij JJS, Verhoeven JE
Sleep 2019 Oct 9;42(10) doi: 10.1093/sleep/zsz139. PMID: 31270544
Sleep and risk of parkinsonism and Parkinson's disease: a population-based study.
Lysen TS, Darweesh SKL, Ikram MK, Luik AI, Ikram MA
Brain 2019 Jul 1;142(7):2013-2022. doi: 10.1093/brain/awz113. PMID: 31038176Free PMC Article
Obstructive sleep apnea in severe mental disorders.
Szaulińska K, Pływaczewski R, Sikorska O, Holka-Pokorska J, Wierzbicka A, Wichniak A, Śliwiński P
Psychiatr Pol 2015;49(5):883-95. doi: 10.12740/PP/32566. PMID: 26688840
Sleep and sleep-wake manipulations in bipolar depression.
Riemann D, Voderholzer U, Berger M
Neuropsychobiology 2002;45 Suppl 1:7-12. doi: 10.1159/000049255. PMID: 11893871

Diagnosis

Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3.
Bedawi EO, Stavroulias D, Hedley E, Blyth KG, Kirk A, De Fonseka D, Edwards JG, Internullo E, Corcoran JP, Marchbank A, Panchal R, Caruana E, Kadwani O, Okiror L, Saba T, Purohit M, Mercer RM, Taberham R, Kanellakis N, Condliffe AM, Lewis LG, Addala DN, Asciak R, Banka R, George V, Hassan M, McCracken D, Sundaralingam A, Wrightson JM, Dobson M, West A, Barnes G, Harvey J, Slade M, Chester-Jones M, Dutton S, Miller RF, Maskell NA, Belcher E, Rahman NM
Am J Respir Crit Care Med 2023 Dec 15;208(12):1305-1315. doi: 10.1164/rccm.202305-0854OC. PMID: 37820359Free PMC Article
Chronotherapy.
Cardinali DP, Brown GM, Pandi-Perumal SR
Handb Clin Neurol 2021;179:357-370. doi: 10.1016/B978-0-12-819975-6.00023-6. PMID: 34225975
Sleep and risk of parkinsonism and Parkinson's disease: a population-based study.
Lysen TS, Darweesh SKL, Ikram MK, Luik AI, Ikram MA
Brain 2019 Jul 1;142(7):2013-2022. doi: 10.1093/brain/awz113. PMID: 31038176Free PMC Article
Circadian Disruption Reveals a Correlation of an Oxidative GSH/GSSG Redox Shift with Learning and Impaired Memory in an Alzheimer's Disease Mouse Model.
LeVault KR, Tischkau SA, Brewer GJ
J Alzheimers Dis 2016;49(2):301-16. doi: 10.3233/JAD-150026. PMID: 26484899
Obstructive sleep apnea in severe mental disorders.
Szaulińska K, Pływaczewski R, Sikorska O, Holka-Pokorska J, Wierzbicka A, Wichniak A, Śliwiński P
Psychiatr Pol 2015;49(5):883-95. doi: 10.12740/PP/32566. PMID: 26688840

Therapy

Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3.
Bedawi EO, Stavroulias D, Hedley E, Blyth KG, Kirk A, De Fonseka D, Edwards JG, Internullo E, Corcoran JP, Marchbank A, Panchal R, Caruana E, Kadwani O, Okiror L, Saba T, Purohit M, Mercer RM, Taberham R, Kanellakis N, Condliffe AM, Lewis LG, Addala DN, Asciak R, Banka R, George V, Hassan M, McCracken D, Sundaralingam A, Wrightson JM, Dobson M, West A, Barnes G, Harvey J, Slade M, Chester-Jones M, Dutton S, Miller RF, Maskell NA, Belcher E, Rahman NM
Am J Respir Crit Care Med 2023 Dec 15;208(12):1305-1315. doi: 10.1164/rccm.202305-0854OC. PMID: 37820359Free PMC Article
Sleeping beauty generated CD19 CAR T-Cell therapy for advanced B-Cell hematological malignancies.
Singh H, Srour SA, Milton DR, McCarty J, Dai C, Gaballa MR, Ammari M, Olivares S, Huls H, De Groot E, Marin D, Petropoulos D, Olson AL, Anderlini P, Im JS, Khouri I, Hosing CM, Rezvani K, Champlin RE, Shpall EJ, Cooper LJN, Kebriaei P
Front Immunol 2022;13:1032397. Epub 2022 Nov 10 doi: 10.3389/fimmu.2022.1032397. PMID: 36439104Free PMC Article
Long-term melatonin treatment for the sleep problems and aberrant behaviors of children with neurodevelopmental disorders.
Yuge K, Nagamitsu S, Ishikawa Y, Hamada I, Takahashi H, Sugioka H, Yotsuya O, Mishima K, Hayashi M, Yamashita Y
BMC Psychiatry 2020 Sep 10;20(1):445. doi: 10.1186/s12888-020-02847-y. PMID: 32912180Free PMC Article
Some implications of melatonin use in chronopharmacology of insomnia.
Golombek DA, Pandi-Perumal SR, Brown GM, Cardinali DP
Eur J Pharmacol 2015 Sep 5;762:42-8. Epub 2015 May 21 doi: 10.1016/j.ejphar.2015.05.032. PMID: 26004526
Transtracheal oxygen therapy.
Christopher KL, Schwartz MD
Chest 2011 Feb;139(2):435-440. doi: 10.1378/chest.10-1373. PMID: 21285058

Prognosis

Macro and micro-sleep dysfunctions as translational biomarkers for Parkinson's disease.
Lima MMS, Targa ADS, Dos Santos Lima GZ, Cavarsan CF, Torterolo P
Int Rev Neurobiol 2024;174:187-209. Epub 2023 Dec 1 doi: 10.1016/bs.irn.2023.08.008. PMID: 38341229
Gender differences in the interference of sleep difficulties and daytime sleepiness on school and social activities in adolescents.
Forest G, Gaudreault P, Michaud F, Green-Demers I
Sleep Med 2022 Dec;100:79-84. Epub 2022 Aug 7 doi: 10.1016/j.sleep.2022.07.020. PMID: 36029754
Chronic Sleep Reduction in Childhood and Adolescence.
Paschke K, Laurenz L, Thomasius R
Dtsch Arztebl Int 2020 Oct 2;117(40):661-667. doi: 10.3238/arztebl.2020.0661. PMID: 33357350Free PMC Article
Disrupted sleep maintenance is associated with altered circadian phase and phase angle in community-dwelling adults.
Kim SJ, Lim YC, Suh IB, Lee JH
Sleep Med 2020 Sep;73:250-256. Epub 2020 Feb 29 doi: 10.1016/j.sleep.2020.02.017. PMID: 32444218
Delayed sleep-onset and biological age: late sleep-onset is associated with shorter telomere length.
Wynchank D, Bijlenga D, Penninx BW, Lamers F, Beekman AT, Kooij JJS, Verhoeven JE
Sleep 2019 Oct 9;42(10) doi: 10.1093/sleep/zsz139. PMID: 31270544

Clinical prediction guides

Macro and micro-sleep dysfunctions as translational biomarkers for Parkinson's disease.
Lima MMS, Targa ADS, Dos Santos Lima GZ, Cavarsan CF, Torterolo P
Int Rev Neurobiol 2024;174:187-209. Epub 2023 Dec 1 doi: 10.1016/bs.irn.2023.08.008. PMID: 38341229
Chronic Sleep Reduction in Childhood and Adolescence.
Paschke K, Laurenz L, Thomasius R
Dtsch Arztebl Int 2020 Oct 2;117(40):661-667. doi: 10.3238/arztebl.2020.0661. PMID: 33357350Free PMC Article
Disrupted sleep maintenance is associated with altered circadian phase and phase angle in community-dwelling adults.
Kim SJ, Lim YC, Suh IB, Lee JH
Sleep Med 2020 Sep;73:250-256. Epub 2020 Feb 29 doi: 10.1016/j.sleep.2020.02.017. PMID: 32444218
Delayed sleep-onset and biological age: late sleep-onset is associated with shorter telomere length.
Wynchank D, Bijlenga D, Penninx BW, Lamers F, Beekman AT, Kooij JJS, Verhoeven JE
Sleep 2019 Oct 9;42(10) doi: 10.1093/sleep/zsz139. PMID: 31270544
Resolution of migraine attacks: sleep and the recovery phase.
Blau JN
J Neurol Neurosurg Psychiatry 1982 Mar;45(3):223-6. doi: 10.1136/jnnp.45.3.223. PMID: 7086442Free PMC Article

Recent systematic reviews

Self-reported poor quality of sleep in solid organ transplant: A systematic review.
Cordoza M, Koons B, Perlis ML, Anderson BJ, Diamond JM, Riegel B
Transplant Rev (Orlando) 2021 Dec;35(4):100650. Epub 2021 Sep 14 doi: 10.1016/j.trre.2021.100650. PMID: 34534733Free PMC Article
Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome.
Naheed B, Kuiper JH, Uthman OA, O'Mahony F, O'Brien PM
Cochrane Database Syst Rev 2017 Mar 3;3(3):CD010503. doi: 10.1002/14651858.CD010503.pub2. PMID: 28257559Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...