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Skin Atypical Lipomatous Tumor/Well Differentiated Liposarcoma

MedGen UID:
1753798
Concept ID:
C5418575
Neoplastic Process
Synonyms: Skin ALT/WDLPS; Skin Atypical Lipomatous Tumor; Skin Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma

Definition

A rare atypical lipomatous tumor/well differentiated liposarcoma arising from the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin Atypical Lipomatous Tumor/Well Differentiated Liposarcoma

Professional guidelines

PubMed

Tardío JC, Pinedo F, Aramburu JA, Martínez-González MÁ, Arias D, Khedaoui R, Suárez-Massa D, Santonja C
Am J Dermatopathol 2016 Aug;38(8):586-92. doi: 10.1097/DAD.0000000000000465. PMID: 26848640
Verweij J, Baker LH
Eur J Cancer 2010 Mar;46(5):863-8. doi: 10.1016/j.ejca.2010.01.016. PMID: 20138507
Potter GK, Ward KA
Clin Podiatr Med Surg 1996 Jan;13(1):155-72. PMID: 8849939

Recent clinical studies

Etiology

Sargen MR, Kim J, Potjer TP, Velthuizen ME, Martir-Negron AE, Odia Y, Helgadottir H, Hatton JN, Haley JS, Thone G, Widemann BC, Gross AM, Yohe ME, Kaplan RN, Shern JF, Sundby RT, Astiazaran-Symonds E, Yang XR, Carey DJ, Tucker MA, Stewart DR, Goldstein AM
JAMA Dermatol 2023 Oct 1;159(10):1112-1118. doi: 10.1001/jamadermatol.2023.2621. PMID: 37585199Free PMC Article
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-648. doi: 10.1111/ddg.13249. PMID: 28591457
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-649. doi: 10.1111/ddg.13249_g. PMID: 28591446
Ferrando PM, Garagnani L, Eckersley R, Weir J, Katsarma E
Ann Ital Chir 2014 Nov-Dec;85(6):587-92. PMID: 25711957
Kovalyshyn I, Braun R, Marghoob A
Australas J Dermatol 2009 Nov;50(4):231-40; quiz 241-2. doi: 10.1111/j.1440-0960.2009.00553_1.x. PMID: 19916964

Diagnosis

Sargen MR, Kim J, Potjer TP, Velthuizen ME, Martir-Negron AE, Odia Y, Helgadottir H, Hatton JN, Haley JS, Thone G, Widemann BC, Gross AM, Yohe ME, Kaplan RN, Shern JF, Sundby RT, Astiazaran-Symonds E, Yang XR, Carey DJ, Tucker MA, Stewart DR, Goldstein AM
JAMA Dermatol 2023 Oct 1;159(10):1112-1118. doi: 10.1001/jamadermatol.2023.2621. PMID: 37585199Free PMC Article
Cammareri C, Beltzung F, Michal M, Vanhersecke L, Coindre JM, Velasco V, Le Loarer F, Vergier B, Perret R
Virchows Arch 2023 Aug;483(2):145-156. Epub 2023 Jul 21 doi: 10.1007/s00428-023-03606-6. PMID: 37477762
Kaczorowski M, Chłopek M, Kruczak A, Ryś J, Lasota J, Miettinen M
Am J Surg Pathol 2022 Nov 1;46(11):1467-1476. Epub 2022 Aug 16 doi: 10.1097/PAS.0000000000001944. PMID: 35973038Free PMC Article
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-648. doi: 10.1111/ddg.13249. PMID: 28591457
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-649. doi: 10.1111/ddg.13249_g. PMID: 28591446

Therapy

Saerens M, Brusselaers N, Rottey S, Decruyenaere A, Creytens D, Lapeire L
Eur J Cancer 2021 Jul;152:165-182. Epub 2021 Jun 6 doi: 10.1016/j.ejca.2021.04.034. PMID: 34107450
Esaa FS, Hobson JG, Matar RN, Prieto PA, Somers KE
Dermatol Online J 2020 Jan 15;26(1) PMID: 32155033
Han T, Luan Y, Xu Y, Yang X, Li J, Liu R, Li Q, Zheng Z
Cancer Biol Ther 2017 Sep 2;18(9):635-639. Epub 2017 Jul 5 doi: 10.1080/15384047.2017.1345394. PMID: 28678611Free PMC Article
Sandoval M, Giesen L, Cataldo K, Gonzalez S
Am J Dermatopathol 2015 Jul;37(7):587-9. doi: 10.1097/DAD.0000000000000139. PMID: 24945757
Nguyen T, Zuniga R
FP Essent 2013 Apr;407:24-30. PMID: 23600336

Prognosis

Bourgeau M, Gandhi JS, Deeb KK, Bahrami A
Hum Pathol 2024 Mar;145:63-70. Epub 2024 Feb 27 doi: 10.1016/j.humpath.2024.02.008. PMID: 38423223
Košec A, Zurak K, Čupić H, Bedeković V
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Oct;136(5):405-408. Epub 2019 Mar 12 doi: 10.1016/j.anorl.2018.01.013. PMID: 30876853
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-648. doi: 10.1111/ddg.13249. PMID: 28591457
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-649. doi: 10.1111/ddg.13249_g. PMID: 28591446
Mentzel T
Semin Diagn Pathol 2001 Nov;18(4):250-7. PMID: 11757864

Clinical prediction guides

Tanabe M, Matsui H, Higashi M, Tokumitsu Y, Nagano H, Ito K
Abdom Radiol (NY) 2022 Jun;47(6):1912-1916. Epub 2022 May 4 doi: 10.1007/s00261-022-03522-4. PMID: 35507066
Kouhsari LM, LeBoit PE, McCalmont TH, Hinds B, North JP
J Cutan Pathol 2022 Jul;49(7):623-631. Epub 2022 Apr 5 doi: 10.1111/cup.14230. PMID: 35332938
Tardío JC, Pinedo F, Aramburu JA, Martínez-González MÁ, Arias D, Khedaoui R, Suárez-Massa D, Santonja C
Am J Dermatopathol 2016 Aug;38(8):586-92. doi: 10.1097/DAD.0000000000000465. PMID: 26848640
Dei Tos AP
Ann Diagn Pathol 2000 Aug;4(4):252-66. doi: 10.1053/adpa.2000.8133. PMID: 10982304
Duve S, Müller-Höcker J, Worret WI
Am J Dermatopathol 1995 Oct;17(5):529-33. doi: 10.1097/00000372-199510000-00017. PMID: 8599462

Recent systematic reviews

Saerens M, Brusselaers N, Rottey S, Decruyenaere A, Creytens D, Lapeire L
Eur J Cancer 2021 Jul;152:165-182. Epub 2021 Jun 6 doi: 10.1016/j.ejca.2021.04.034. PMID: 34107450

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