Locally Advanced Gallbladder Carcinoma

MedGen UID:: 1740191
•Concept ID:: C5418568
•: Neoplastic Process

Definition

Gallbladder carcinoma that has spread to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVLocally Advanced Gallbladder Carcinoma

Metastatic malignant neoplasm
- Locally Advanced Malignant Neoplasm
  - Locally Advanced Carcinoma
    - Locally Advanced Digestive System Carcinoma
      - Locally Advanced Pancreatobiliary Carcinoma
        Locally Advanced Biliary Tract Carcinoma
        Locally Advanced Gallbladder Carcinoma

Professional guidelines

PubMed

Biliary tract cancers: French national clinical practice guidelines for diagnosis, treatments and follow-up (TNCD, SNFGE, FFCD, UNICANCER, GERCOR, SFCD, SFED, AFEF, SFRO, SFP, SFR, ACABi, ACHBPT).

Roth GS, Verlingue L, Sarabi M, Blanc JF, Boleslawski E, Boudjema K, Bretagne-Bignon AL, Camus-Duboc M, Coriat R, Créhange G, De Baere T, de la Fouchardière C, Dromain C, Edeline J, Gelli M, Guiu B, Horn S, Laurent-Croise V, Lepage C, Lièvre A, Lopez A, Manfredi S, Meilleroux J, Neuzillet C, Paradis V, Prat F, Ronot M, Rosmorduc O, Cunha AS, Soubrane O, Turpin A, Louvet C, Bouché O, Malka D
Eur J Cancer 2024 May;202:114000. Epub 2024 Mar 13 doi: 10.1016/j.ejca.2024.114000. PMID: 38493667

Dysplasia and carcinoma of the gallbladder: pathological evaluation, sampling, differential diagnosis and clinical implications.

Roa JC, Basturk O, Adsay V
Histopathology 2021 Jul;79(1):2-19. Epub 2021 May 6 doi: 10.1111/his.14360. PMID: 33629395

Locally advanced gallbladder cancer: a review of the criteria and role of imaging.

Gupta P, Meghashyam K, Marodia Y, Gupta V, Basher R, Das CK, Yadav TD, Irrinki S, Nada R, Dutta U
Abdom Radiol (NY) 2021 Mar;46(3):998-1007. Epub 2020 Sep 18 doi: 10.1007/s00261-020-02756-4. PMID: 32945922

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Recent clinical studies

Etiology

Comparison of Chemotherapy Combined with Percutaneous Electroporation and Chemotherapy Alone in the Management of Locally Advanced Gallbladder Carcinoma (GBC): A Study Protocol.

Kalra N, Bhujade H, Baloji A, Khosla D, Samra S, Srinivasan R, Gupta P, Singh H, Gupta V, Kapoor R, Dahiya D, Gupta R, Kishore K, Sandhu M
Cardiovasc Intervent Radiol 2024 Nov;47(11):1532-1539. Epub 2024 Sep 27 doi: 10.1007/s00270-024-03856-0. PMID: 39333372

Towards standardization of management of gallbladder carcinoma with obstructive jaundice: Analysis of 113 cases over 10 years at a single institution.

Goel M, Gupta AM, Patkar S, Parray AM, Shetty N, Ramaswamy A, Patil P, Chopra S, Ostwal V, Kulkarni S, Engineer R, Mehta S
J Surg Oncol 2021 Sep;124(4):572-580. Epub 2021 Jun 9 doi: 10.1002/jso.26564. PMID: 34106475

Systemic Chemotherapy Combined with Resection for Locally Advanced Gallbladder Carcinoma: Surgical and Survival Outcomes.

Creasy JM, Goldman DA, Dudeja V, Lowery MA, Cercek A, Balachandran VP, Allen PJ, DeMatteo RP, Kingham TP, D'Angelica MI, Jarnagin WR
J Am Coll Surg 2017 May;224(5):906-916. Epub 2017 Feb 13 doi: 10.1016/j.jamcollsurg.2016.12.058. PMID: 28216422 Free PMC Article

Combined extrahepatic bile duct resection for locally advanced gallbladder carcinoma: does it work?

Igami T, Ebata T, Yokoyama Y, Sugawara G, Mizuno T, Yamaguchi J, Shimoyama Y, Nagino M
World J Surg 2015 Jul;39(7):1810-7. doi: 10.1007/s00268-015-3011-y. PMID: 25663014

Surgical outcomes of minor hepatectomy for locally advanced gallbladder carcinoma.

Wakai T, Shirai Y, Sakata J, Tsuchiya Y, Nomura T, Hatakeyama K
Hepatogastroenterology 2012 Oct;59(119):2083-8. doi: 10.5754/hge12097. PMID: 22456433

See all (8)

Therapy

Comparison of Chemotherapy Combined with Percutaneous Electroporation and Chemotherapy Alone in the Management of Locally Advanced Gallbladder Carcinoma (GBC): A Study Protocol.

Towards standardization of management of gallbladder carcinoma with obstructive jaundice: Analysis of 113 cases over 10 years at a single institution.

Gallbladder cancer with EGFR mutation and its response to GemOx with erlotinib: a case report and review of literature.

Soni K, Kumar T, Pandey M
World J Surg Oncol 2020 Jul 4;18(1):153. doi: 10.1186/s12957-020-01934-4. PMID: 32622356 Free PMC Article

Systemic Chemotherapy Combined with Resection for Locally Advanced Gallbladder Carcinoma: Surgical and Survival Outcomes.

Surgical outcomes of minor hepatectomy for locally advanced gallbladder carcinoma.

Wakai T, Shirai Y, Sakata J, Tsuchiya Y, Nomura T, Hatakeyama K
Hepatogastroenterology 2012 Oct;59(119):2083-8. doi: 10.5754/hge12097. PMID: 22456433

See all (5)

Prognosis

Towards standardization of management of gallbladder carcinoma with obstructive jaundice: Analysis of 113 cases over 10 years at a single institution.

Gallbladder cancer with EGFR mutation and its response to GemOx with erlotinib: a case report and review of literature.

Soni K, Kumar T, Pandey M
World J Surg Oncol 2020 Jul 4;18(1):153. doi: 10.1186/s12957-020-01934-4. PMID: 32622356 Free PMC Article

Systemic Chemotherapy Combined with Resection for Locally Advanced Gallbladder Carcinoma: Surgical and Survival Outcomes.

Combined extrahepatic bile duct resection for locally advanced gallbladder carcinoma: does it work?

Igami T, Ebata T, Yokoyama Y, Sugawara G, Mizuno T, Yamaguchi J, Shimoyama Y, Nagino M
World J Surg 2015 Jul;39(7):1810-7. doi: 10.1007/s00268-015-3011-y. PMID: 25663014

Combined pancreaticoduodenectomy and hepatectomy for patients with locally advanced gallbladder carcinoma: long term results.

Shirai Y, Ohtani T, Tsukada K, Hatakeyama K
Cancer 1997 Nov 15;80(10):1904-9. PMID: 9366291

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