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Locally Advanced Undifferentiated Pleomorphic Sarcoma

MedGen UID:
1693088
Concept ID:
C5205658
Neoplastic Process

Definition

An undifferentiated pleomorphic sarcoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Undifferentiated Pleomorphic Sarcoma

Professional guidelines

PubMed

Kokkali S, Moreno JD, Klijanienko J, Theocharis S
Int J Mol Sci 2022 Apr 8;23(8) doi: 10.3390/ijms23084125. PMID: 35456944Free PMC Article
Mijušković Ž, Brašanac D, Rajović M, Sekulović LK
JCO Oncol Pract 2020 Dec;16(12):839-841. Epub 2020 Aug 19 doi: 10.1200/OP.20.00405. PMID: 32813586
Nakamura T, Tsukushi S, Asanuma K, Katagiri H, Ikuta K, Nagano A, Kozawa E, Yamada S, Shido Y, Yamada K, Kawanami K, Ishimura D, Sudo A, Nishida Y
Clin Exp Metastasis 2019 Aug;36(4):343-350. Epub 2019 Jun 17 doi: 10.1007/s10585-019-09980-3. PMID: 31209624

Recent clinical studies

Etiology

Ramakrishnan K, Levy N, Goldbach A, Nagarathinam R, Ali S, Ling S, Jonnalagadda P
Curr Probl Diagn Radiol 2022 Nov-Dec;51(6):868-877. Epub 2022 May 2 doi: 10.1067/j.cpradiol.2022.04.005. PMID: 35654634
García-Ortega DY, Melendez-Fernandez AP, Alvarez-Cano A, Clara-Altamirano MA, Caro-Sanchez C, Alamilla-Garcia G, Luna-Ortiz K
Surg Oncol 2022 Jun;42:101746. Epub 2022 Mar 29 doi: 10.1016/j.suronc.2022.101746. PMID: 35378375
Tang F, Tie Y, Wei YQ, Tu CQ, Wei XW
Biochim Biophys Acta Rev Cancer 2021 Dec;1876(2):188606. Epub 2021 Aug 8 doi: 10.1016/j.bbcan.2021.188606. PMID: 34371128
Kokkali S, Stravodimou A, Duran-Moreno J, Koufopoulos N, Voutsadakis IA, Digklia A
Expert Rev Anticancer Ther 2021 Jun;21(6):591-604. Epub 2021 Mar 12 doi: 10.1080/14737140.2021.1880327. PMID: 33554686
Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S
Lancet Oncol 2017 Nov;18(11):1493-1501. Epub 2017 Oct 4 doi: 10.1016/S1470-2045(17)30624-1. PMID: 28988646Free PMC Article

Diagnosis

Graves L, Jeck WR, Grilley-Olson JE
Curr Treat Options Oncol 2023 Mar;24(3):212-228. Epub 2023 Feb 2 doi: 10.1007/s11864-023-01054-7. PMID: 36729198
García-Ortega DY, Melendez-Fernandez AP, Alvarez-Cano A, Clara-Altamirano MA, Caro-Sanchez C, Alamilla-Garcia G, Luna-Ortiz K
Surg Oncol 2022 Jun;42:101746. Epub 2022 Mar 29 doi: 10.1016/j.suronc.2022.101746. PMID: 35378375
Kokkali S, Stravodimou A, Duran-Moreno J, Koufopoulos N, Voutsadakis IA, Digklia A
Expert Rev Anticancer Ther 2021 Jun;21(6):591-604. Epub 2021 Mar 12 doi: 10.1080/14737140.2021.1880327. PMID: 33554686
Cannatella J, Ganapathi K, Horvai A
Arch Pathol Lab Med 2020 Dec 1;144(12):1547-1552. doi: 10.5858/arpa.2019-0580-OA. PMID: 32167380
Wapshott T, Schammel CMG, Schammel DP, Rezeanu L, Lynn M
J Clin Neurosci 2018 Aug;54:128-135. Epub 2018 May 21 doi: 10.1016/j.jocn.2018.04.060. PMID: 29793776

Therapy

Tang F, Tie Y, Wei YQ, Tu CQ, Wei XW
Biochim Biophys Acta Rev Cancer 2021 Dec;1876(2):188606. Epub 2021 Aug 8 doi: 10.1016/j.bbcan.2021.188606. PMID: 34371128
Mijušković Ž, Brašanac D, Rajović M, Sekulović LK
JCO Oncol Pract 2020 Dec;16(12):839-841. Epub 2020 Aug 19 doi: 10.1200/OP.20.00405. PMID: 32813586
Keung EZ, Lazar AJ, Torres KE, Wang WL, Cormier JN, Ashleigh Guadagnolo B, Bishop AJ, Lin H, Hunt KK, Bird J, Lewis VO, Patel SR, Wargo JA, Somaiah N, Roland CL
BMC Cancer 2018 Sep 24;18(1):913. doi: 10.1186/s12885-018-4829-0. PMID: 30249211Free PMC Article
Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S
Lancet Oncol 2017 Nov;18(11):1493-1501. Epub 2017 Oct 4 doi: 10.1016/S1470-2045(17)30624-1. PMID: 28988646Free PMC Article
Jain A, Sajeevan KV, Babu KG, Lakshmaiah KC
Indian J Cancer 2009 Oct-Dec;46(4):274-87. doi: 10.4103/0019-509X.55547. PMID: 19749457

Prognosis

Pan M, Zhou MY, Jiang C, Zhang Z, Bui NQ, Bien J, Siy A, Achacoso N, Solorzano AV, Tse P, Chung E, Thomas S, Habel LA, Ganjoo KN
Clin Cancer Res 2024 Jan 17;30(2):413-419. doi: 10.1158/1078-0432.CCR-23-1990. PMID: 37831066Free PMC Article
Graves L, Jeck WR, Grilley-Olson JE
Curr Treat Options Oncol 2023 Mar;24(3):212-228. Epub 2023 Feb 2 doi: 10.1007/s11864-023-01054-7. PMID: 36729198
García-Ortega DY, Melendez-Fernandez AP, Alvarez-Cano A, Clara-Altamirano MA, Caro-Sanchez C, Alamilla-Garcia G, Luna-Ortiz K
Surg Oncol 2022 Jun;42:101746. Epub 2022 Mar 29 doi: 10.1016/j.suronc.2022.101746. PMID: 35378375
Wapshott T, Schammel CMG, Schammel DP, Rezeanu L, Lynn M
J Clin Neurosci 2018 Aug;54:128-135. Epub 2018 May 21 doi: 10.1016/j.jocn.2018.04.060. PMID: 29793776
Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S
Lancet Oncol 2017 Nov;18(11):1493-1501. Epub 2017 Oct 4 doi: 10.1016/S1470-2045(17)30624-1. PMID: 28988646Free PMC Article

Clinical prediction guides

Graves L, Jeck WR, Grilley-Olson JE
Curr Treat Options Oncol 2023 Mar;24(3):212-228. Epub 2023 Feb 2 doi: 10.1007/s11864-023-01054-7. PMID: 36729198
García-Ortega DY, Melendez-Fernandez AP, Alvarez-Cano A, Clara-Altamirano MA, Caro-Sanchez C, Alamilla-Garcia G, Luna-Ortiz K
Surg Oncol 2022 Jun;42:101746. Epub 2022 Mar 29 doi: 10.1016/j.suronc.2022.101746. PMID: 35378375
Goy BW, Syed S, Padmanabhan A, Burchette RJ, Helmstedter CS
Radiother Oncol 2021 Dec;165:174-178. Epub 2021 Nov 7 doi: 10.1016/j.radonc.2021.10.019. PMID: 34758339
Cornillie J, Wozniak A, Li H, Wang Y, Boeckx B, Gebreyohannes YK, Wellens J, Vanleeuw U, Hompes D, Stas M, Sinnaeve F, Wafa H, Lambrechts D, Debiec-Rychter M, Sciot R, Schöffski P
Mol Cancer Ther 2019 Jun;18(6):1168-1178. Epub 2019 Apr 8 doi: 10.1158/1535-7163.MCT-18-1045. PMID: 30962320
Neuwirth MG, Song Y, Sinnamon AJ, Fraker DL, Zager JS, Karakousis GC
Ann Surg Oncol 2017 Dec;24(13):3803-3810. Epub 2017 Oct 11 doi: 10.1245/s10434-017-6109-7. PMID: 29022281

Recent systematic reviews

Neuwirth MG, Song Y, Sinnamon AJ, Fraker DL, Zager JS, Karakousis GC
Ann Surg Oncol 2017 Dec;24(13):3803-3810. Epub 2017 Oct 11 doi: 10.1245/s10434-017-6109-7. PMID: 29022281

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