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Recurrent Rectal Adenocarcinoma

MedGen UID:
1691586
•Concept ID:
C0861754
•
Neoplastic Process

Definition

The reemergence of rectal adenocarcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Rectal Adenocarcinoma

Professional guidelines

PubMed

Multimodality Imaging to Direct Management of Primary and Recurrent Rectal Adenocarcinoma Beyond the Total Mesorectal Excision Plane.
Shur JD, Qiu S, Johnston E, Tait D, Fotiadis N, Kontovounisios C, Rasheed S, Tekkis P, Riddell A, Koh DM
Radiol Imaging Cancer 2024 Mar;6(2):e230077. doi: 10.1148/rycan.230077. PMID: 38363197Free PMC Article
The role of intra-operative irradiation in locally advanced primary and recurrent rectal adenocarcinoma.
Gunderson LL, O'Connell MJ, Dozois RR
World J Surg 1992 May-Jun;16(3):495-501. doi: 10.1007/BF02104454. PMID: 1589987
Hyperthermic pelvic isolation-perfusion in the treatment of refractory pelvic cancer.
Wile A, Smolin M
Arch Surg 1987 Nov;122(11):1321-5. doi: 10.1001/archsurg.1987.01400230107019. PMID: 3675195

Recent clinical studies

Etiology

Rectal cancer presentation during the COVID-19 pandemic: Are decreasing screening rates leading to an increase in acute presentations?
Sutton TS, Hao S, Suzuki M, Chua A, Ciarrocca AL, Honaker MD
PLoS One 2023;18(9):e0291447. Epub 2023 Sep 14 doi: 10.1371/journal.pone.0291447. PMID: 37708208Free PMC Article
Systematic Review of Pelvic Exenteration With En Bloc Sacrectomy for Recurrent Rectal Adenocarcinoma: R0 Resection Predicts Disease-free Survival.
Sasikumar A, Bhan C, Jenkins JT, Antoniou A, Murphy J
Dis Colon Rectum 2017 Mar;60(3):346-352. doi: 10.1097/DCR.0000000000000737. PMID: 28177998
Hyperfractionated accelerated reirradiation for rectal cancer: An analysis of outcomes and toxicity.
Tao R, Tsai CJ, Jensen G, Eng C, Kopetz S, Overman MJ, Skibber JM, Rodriguez-Bigas M, Chang GJ, You YN, Bednarski BK, Minsky BD, Delclos ME, Koay E, Krishnan S, Crane CH, Das P
Radiother Oncol 2017 Jan;122(1):146-151. Epub 2017 Jan 3 doi: 10.1016/j.radonc.2016.12.015. PMID: 28057329
Palliative reirradiation for recurrent rectal cancer.
Lingareddy V, Ahmad NR, Mohiuddin M
Int J Radiat Oncol Biol Phys 1997 Jul 1;38(4):785-90. doi: 10.1016/s0360-3016(97)00058-8. PMID: 9240647
Surgery for recurrent rectal adenocarcinoma in the presence of hydronephrosis.
Rodriguez-Bigas MA, Herrera L, Petrelli NJ
Am J Surg 1992 Jul;164(1):18-21. doi: 10.1016/s0002-9610(05)80639-7. PMID: 1626601

Diagnosis

Rectal cancer presentation during the COVID-19 pandemic: Are decreasing screening rates leading to an increase in acute presentations?
Sutton TS, Hao S, Suzuki M, Chua A, Ciarrocca AL, Honaker MD
PLoS One 2023;18(9):e0291447. Epub 2023 Sep 14 doi: 10.1371/journal.pone.0291447. PMID: 37708208Free PMC Article
The rare BRAF VK600-601E mutation as a possible indicator of poor prognosis in rectal carcinoma – a report of a case.
Mori Y, Nagasaka T, Mishima H, Umeda Y, Inada R, Kishimoto H, Goel A, Fujiwara T
BMC Med Genet 2015 Jan 31;16:1. doi: 10.1186/s12881-015-0144-7. PMID: 25636897Free PMC Article
Diagnosis of recurrent rectal cancer deep into the vaginal wall by transvaginal endoscopic ultrasound-guided fine needle aspiration.
Kongkam P, LeBlanc JK
Endoscopy 2008 Oct;40(10):873-4. Epub 2008 Jul 21 doi: 10.1055/s-2008-1077468. PMID: 18645930
The implications of an incidental chronic lymphocytic leukaemia in a resection specimen for colorectal adenocarcinoma.
Dennis RJ, Alberts JC
World J Surg Oncol 2007 Oct 30;5:126. doi: 10.1186/1477-7819-5-126. PMID: 17971235Free PMC Article
Is there a role for curative surgery for pelvic recurrence from rectal carcinoma in the presence of hydronephrosis?
Cheng C, Rodriguez-Bigas MA, Petrelli N
Am J Surg 2001 Sep;182(3):274-7. doi: 10.1016/s0002-9610(01)00706-1. PMID: 11587692

Therapy

CT-guided radiofrequency ablation in the treatment of recurrent rectal cancer.
Belfiore G, Tedeschi E, Ronza FM, Belfiore MP, Borsi E, Ianniello GP, Rotondo A
AJR Am J Roentgenol 2009 Jan;192(1):137-41. doi: 10.2214/AJR.07.2649. PMID: 19098192
The implications of an incidental chronic lymphocytic leukaemia in a resection specimen for colorectal adenocarcinoma.
Dennis RJ, Alberts JC
World J Surg Oncol 2007 Oct 30;5:126. doi: 10.1186/1477-7819-5-126. PMID: 17971235Free PMC Article
Treatment of non-resectable pelvic malignancies by isolated pelvic perfusion. A preliminary study.
Kocaoglu H, Yerdel MA, Cetin R, Demirci S, Unal M
Eur J Surg Oncol 1995 Oct;21(5):535-40. doi: 10.1016/s0748-7983(95)97194-7. PMID: 7589601
The role of intra-operative irradiation in locally advanced primary and recurrent rectal adenocarcinoma.
Gunderson LL, O'Connell MJ, Dozois RR
World J Surg 1992 May-Jun;16(3):495-501. doi: 10.1007/BF02104454. PMID: 1589987
Hyperthermic pelvic isolation-perfusion in the treatment of refractory pelvic cancer.
Wile A, Smolin M
Arch Surg 1987 Nov;122(11):1321-5. doi: 10.1001/archsurg.1987.01400230107019. PMID: 3675195

Prognosis

Systematic Review of Pelvic Exenteration With En Bloc Sacrectomy for Recurrent Rectal Adenocarcinoma: R0 Resection Predicts Disease-free Survival.
Sasikumar A, Bhan C, Jenkins JT, Antoniou A, Murphy J
Dis Colon Rectum 2017 Mar;60(3):346-352. doi: 10.1097/DCR.0000000000000737. PMID: 28177998
Hyperfractionated accelerated reirradiation for rectal cancer: An analysis of outcomes and toxicity.
Tao R, Tsai CJ, Jensen G, Eng C, Kopetz S, Overman MJ, Skibber JM, Rodriguez-Bigas M, Chang GJ, You YN, Bednarski BK, Minsky BD, Delclos ME, Koay E, Krishnan S, Crane CH, Das P
Radiother Oncol 2017 Jan;122(1):146-151. Epub 2017 Jan 3 doi: 10.1016/j.radonc.2016.12.015. PMID: 28057329
Radical redo surgery for local rectal cancer recurrence improves overall survival: a single center experience.
Schurr P, Lentz E, Block S, Kaifi J, Kleinhans H, Cataldegirmen G, Kutup A, Schneider C, Strate T, Yekebas E, Izbicki J
J Gastrointest Surg 2008 Jul;12(7):1232-8. Epub 2008 Apr 30 doi: 10.1007/s11605-008-0517-8. PMID: 18446418
Palliative reirradiation for recurrent rectal cancer.
Lingareddy V, Ahmad NR, Mohiuddin M
Int J Radiat Oncol Biol Phys 1997 Jul 1;38(4):785-90. doi: 10.1016/s0360-3016(97)00058-8. PMID: 9240647
Surgery for recurrent rectal adenocarcinoma in the presence of hydronephrosis.
Rodriguez-Bigas MA, Herrera L, Petrelli NJ
Am J Surg 1992 Jul;164(1):18-21. doi: 10.1016/s0002-9610(05)80639-7. PMID: 1626601

Clinical prediction guides

Systematic Review of Pelvic Exenteration With En Bloc Sacrectomy for Recurrent Rectal Adenocarcinoma: R0 Resection Predicts Disease-free Survival.
Sasikumar A, Bhan C, Jenkins JT, Antoniou A, Murphy J
Dis Colon Rectum 2017 Mar;60(3):346-352. doi: 10.1097/DCR.0000000000000737. PMID: 28177998
CT-guided radiofrequency ablation in the treatment of recurrent rectal cancer.
Belfiore G, Tedeschi E, Ronza FM, Belfiore MP, Borsi E, Ianniello GP, Rotondo A
AJR Am J Roentgenol 2009 Jan;192(1):137-41. doi: 10.2214/AJR.07.2649. PMID: 19098192
Radical redo surgery for local rectal cancer recurrence improves overall survival: a single center experience.
Schurr P, Lentz E, Block S, Kaifi J, Kleinhans H, Cataldegirmen G, Kutup A, Schneider C, Strate T, Yekebas E, Izbicki J
J Gastrointest Surg 2008 Jul;12(7):1232-8. Epub 2008 Apr 30 doi: 10.1007/s11605-008-0517-8. PMID: 18446418
The implications of an incidental chronic lymphocytic leukaemia in a resection specimen for colorectal adenocarcinoma.
Dennis RJ, Alberts JC
World J Surg Oncol 2007 Oct 30;5:126. doi: 10.1186/1477-7819-5-126. PMID: 17971235Free PMC Article
Hyperthermic pelvic isolation-perfusion in the treatment of refractory pelvic cancer.
Wile A, Smolin M
Arch Surg 1987 Nov;122(11):1321-5. doi: 10.1001/archsurg.1987.01400230107019. PMID: 3675195

Recent systematic reviews

Systematic Review of Pelvic Exenteration With En Bloc Sacrectomy for Recurrent Rectal Adenocarcinoma: R0 Resection Predicts Disease-free Survival.
Sasikumar A, Bhan C, Jenkins JT, Antoniou A, Murphy J
Dis Colon Rectum 2017 Mar;60(3):346-352. doi: 10.1097/DCR.0000000000000737. PMID: 28177998

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