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Resectable Sarcoma

MedGen UID:
1665307
•Concept ID:
C4725866
•
Neoplastic Process

Definition

Sarcoma that is amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

Surgical Management of Metastatic Disease.
Keung EZ, Fairweather M, Raut CP
Surg Clin North Am 2016 Oct;96(5):1175-92. doi: 10.1016/j.suc.2016.05.010. PMID: 27542649
Chemotherapy of soft tissue sarcoma--a clinical evaluation of treatment over ten years.
Wall N, Starkhammar H
Acta Oncol 2003;42(1):55-61. doi: 10.1080/0891060310002249. PMID: 12665332

Recent clinical studies

Etiology

Management of pelvic sarcoma.
Lee JS, Kelly CM, Bartlett EK
Eur J Surg Oncol 2022 Nov;48(11):2299-2307. Epub 2022 Sep 17 doi: 10.1016/j.ejso.2022.09.011. PMID: 36195471
Advances in the Diagnosis and Management of Neonatal Sarcomas.
Rashid T, Noyd DH, Iranzad N, Davis JT, Deel MD
Clin Perinatol 2021 Mar;48(1):117-145. doi: 10.1016/j.clp.2020.11.007. PMID: 33583500
Non-rhabdomyosarcoma.
Dasgupta R, Rodeberg D
Semin Pediatr Surg 2016 Oct;25(5):284-289. Epub 2016 Sep 22 doi: 10.1053/j.sempedsurg.2016.09.012. PMID: 27955731
Retroperitoneal sarcomas.
Kumarasamy NA, Gayer G
Semin Ultrasound CT MR 2011 Oct;32(5):422-32. doi: 10.1053/j.sult.2011.06.002. PMID: 21963163
Soft tissue sarcomas.
Lewis JJ, Brennan MF
Curr Probl Surg 1996 Oct;33(10):817-72. PMID: 8885853

Diagnosis

Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
Non-rhabdomyosarcoma.
Dasgupta R, Rodeberg D
Semin Pediatr Surg 2016 Oct;25(5):284-289. Epub 2016 Sep 22 doi: 10.1053/j.sempedsurg.2016.09.012. PMID: 27955731
Soft-tissue sarcoma.
Gilbert NF, Cannon CP, Lin PP, Lewis VO
J Am Acad Orthop Surg 2009 Jan;17(1):40-7. doi: 10.5435/00124635-200901000-00006. PMID: 19136426
Soft tissue sarcomas.
Lewis JJ, Brennan MF
Curr Probl Surg 1996 Oct;33(10):817-72. PMID: 8885853
Retroperitoneal sarcomas.
McGrath PC
Semin Surg Oncol 1994 Sep-Oct;10(5):364-8. doi: 10.1002/ssu.2980100509. PMID: 7997730

Therapy

Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial.
Bonvalot S, Gronchi A, Le Péchoux C, Swallow CJ, Strauss D, Meeus P, van Coevorden F, Stoldt S, Stoeckle E, Rutkowski P, Rastrelli M, Raut CP, Hompes D, De Paoli A, Sangalli C, Honoré C, Chung P, Miah A, Blay JY, Fiore M, Stelmes JJ, Dei Tos AP, Baldini EH, Litière S, Marreaud S, Gelderblom H, Haas RL
Lancet Oncol 2020 Oct;21(10):1366-1377. Epub 2020 Sep 14 doi: 10.1016/S1470-2045(20)30446-0. PMID: 32941794
Non-rhabdomyosarcoma.
Dasgupta R, Rodeberg D
Semin Pediatr Surg 2016 Oct;25(5):284-289. Epub 2016 Sep 22 doi: 10.1053/j.sempedsurg.2016.09.012. PMID: 27955731
Neoadjuvant Therapy for Soft-Tissue Sarcomas.
Fairweather M, Keung E, Raut CP
Oncology (Williston Park) 2016 Jan;30(1):99-106. PMID: 26791852
Radiation-induced sarcomas.
Mavrogenis AF, Angelini A, Pala E, Calabro T, Bianchi G, Casadei R, Ruggieri P
J Long Term Eff Med Implants 2011;21(3):233-40. doi: 10.1615/jlongtermeffmedimplants.v21.i3.70. PMID: 22150356
Retroperitoneal sarcomas.
Feig BW
Surg Oncol Clin N Am 2003 Apr;12(2):369-77. doi: 10.1016/s1055-3207(03)00004-8. PMID: 12916460

Prognosis

Non-rhabdomyosarcoma soft-tissue sarcoma.
Milgrom SA, Million L, Mandeville H, Safwat A, Ermoian RP, Terezakis S
Pediatr Blood Cancer 2021 May;68 Suppl 2:e28279. doi: 10.1002/pbc.28279. PMID: 33818885
The importance of surgical margins in retroperitoneal sarcoma.
Kirane A, Crago AM
J Surg Oncol 2016 Mar;113(3):270-6. Epub 2015 Dec 28 doi: 10.1002/jso.24135. PMID: 26707028
Radiation-induced sarcomas.
Mavrogenis AF, Angelini A, Pala E, Calabro T, Bianchi G, Casadei R, Ruggieri P
J Long Term Eff Med Implants 2011;21(3):233-40. doi: 10.1615/jlongtermeffmedimplants.v21.i3.70. PMID: 22150356
Soft tissue sarcoma.
Beech DJ
J La State Med Soc 1999 Jan;151(1):33-41. PMID: 11280813
Retroperitoneal sarcomas.
McGrath PC
Semin Surg Oncol 1994 Sep-Oct;10(5):364-8. doi: 10.1002/ssu.2980100509. PMID: 7997730

Clinical prediction guides

Pelvic soft tissue sarcomas.
Sarre-Lazcano C, Dumitra S, Fiore M
Eur J Surg Oncol 2023 Jun;49(6):1102-1110. Epub 2022 Jun 4 doi: 10.1016/j.ejso.2022.06.003. PMID: 35725682
BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas.
Kao YC, Owosho AA, Sung YS, Zhang L, Fujisawa Y, Lee JC, Wexler L, Argani P, Swanson D, Dickson BC, Fletcher CDM, Antonescu CR
Am J Surg Pathol 2018 May;42(5):604-615. doi: 10.1097/PAS.0000000000000965. PMID: 29300189Free PMC Article
Management of recurrent retroperitoneal sarcoma.
Gyorki DE, Brennan MF
J Surg Oncol 2014 Jan;109(1):53-9. Epub 2013 Oct 24 doi: 10.1002/jso.23463. PMID: 24155163
The clinical evaluation of soft tissue tumors.
Balach T, Stacy GS, Haydon RC
Radiol Clin North Am 2011 Nov;49(6):1185-96, vi. doi: 10.1016/j.rcl.2011.07.005. PMID: 22024294
Soft tissue sarcoma: advances in understanding and management.
Brennan MF
Surgeon 2005 Jun;3(3):216-23. doi: 10.1016/s1479-666x(05)80044-7. PMID: 16076008

Recent systematic reviews

Malignant phyllodes tumor of the breast: a systematic review.
Lissidini G, Mulè A, Santoro A, Papa G, Nicosia L, Cassano E, Ashoor AA, Veronesi P, Pantanowitz L, Hornick JL, Rossi ED
Pathologica 2022 Apr;114(2):111-120. Epub 2022 Apr 13 doi: 10.32074/1591-951X-754. PMID: 35414723Free PMC Article
Primary Angiosarcoma of the Gastrointestinal Tract: A Systematic Review of the Literature.
Schizas D, Mastoraki A, Giannakodimos I, Giannakodimos A, Ziogou A, Katsaros I, Frountzas M, Koutelidakis I, Vassiliu P, Pikoulis E
J Invest Surg 2022 Feb;35(2):400-408. Epub 2020 Dec 21 doi: 10.1080/08941939.2020.1853283. PMID: 33342318
Surgical management of tracheal chondrosarcoma.
Rotolo N, Cattoni M, Nardecchia E, De Maio S, Franzi F, Pettenon F, Imperatori A
Acta Chir Belg 2022 Oct;122(5):361-365. Epub 2020 Dec 25 doi: 10.1080/00015458.2020.1863039. PMID: 33306456
Risk Factors for Perimegaprosthetic Infections After Tumor Resection.
De Gori M, Gasparini G, Capanna R
Orthopedics 2017 Jan 1;40(1):e11-e16. Epub 2016 Dec 7 doi: 10.3928/01477447-20161128-01. PMID: 27925637
A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma.
Pervaiz N, Colterjohn N, Farrokhyar F, Tozer R, Figueredo A, Ghert M
Cancer 2008 Aug 1;113(3):573-81. doi: 10.1002/cncr.23592. PMID: 18521899

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