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Resectable Dedifferentiated Liposarcoma

MedGen UID:
1660834
•Concept ID:
C4725868
•
Neoplastic Process

Definition

Dedifferentiated liposarcoma that is amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVResectable Dedifferentiated Liposarcoma

Professional guidelines

PubMed

Retroperitoneal tumors: Review of diagnosis and management.
Sassa N
Int J Urol 2020 Dec;27(12):1058-1070. Epub 2020 Sep 10 doi: 10.1111/iju.14361. PMID: 32914475
Liposarcoma: Multimodality Management and Future Targeted Therapies.
Crago AM, Dickson MA
Surg Oncol Clin N Am 2016 Oct;25(4):761-73. Epub 2016 Jul 30 doi: 10.1016/j.soc.2016.05.007. PMID: 27591497Free PMC Article
Management of Truncal Sarcoma.
Mullinax JE, Gonzalez RJ
Surg Clin North Am 2016 Oct;96(5):1003-13. doi: 10.1016/j.suc.2016.06.005. PMID: 27542639

Recent clinical studies

Etiology

Surgical Management of Retroperitoneal Sarcoma.
Dominguez DA, Sampath S, Agulnik M, Liang Y, Nguyen B, Trisal V, Melstrom LG, Lewis AG, Paz IB, Roberts RF, Tseng WW
Curr Oncol 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349. PMID: 37232807Free PMC Article
Management of Recurrent Retroperitoneal Sarcoma.
Jolissaint JS, Raut CP, Fairweather M
Curr Oncol 2023 Feb 25;30(3):2761-2769. doi: 10.3390/curroncol30030209. PMID: 36975422Free PMC Article
Management of pelvic sarcoma.
Lee JS, Kelly CM, Bartlett EK
Eur J Surg Oncol 2022 Nov;48(11):2299-2307. Epub 2022 Sep 17 doi: 10.1016/j.ejso.2022.09.011. PMID: 36195471
Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142
Liposarcoma: Multimodality Management and Future Targeted Therapies.
Crago AM, Dickson MA
Surg Oncol Clin N Am 2016 Oct;25(4):761-73. Epub 2016 Jul 30 doi: 10.1016/j.soc.2016.05.007. PMID: 27591497Free PMC Article

Diagnosis

Pleomorphic Liposarcoma Revisited.
Hadjimichael AC, Bekos A, Tsukamoto S, Nitta Y, Righi A, Errani C, Mavrogenis AF
Orthopedics 2023 Mar-Apr;46(2):e72-e80. Epub 2022 Jul 25 doi: 10.3928/01477447-20220719-05. PMID: 35876778
Hazardous giant pharyngoesophageal liposarcoma.
Anbarasan S, Mani S, Goel G, Chirom AS
BMJ Case Rep 2022 Nov 10;15(11) doi: 10.1136/bcr-2022-250085. PMID: 36357101Free PMC Article
Retroperitoneal tumors: Review of diagnosis and management.
Sassa N
Int J Urol 2020 Dec;27(12):1058-1070. Epub 2020 Sep 10 doi: 10.1111/iju.14361. PMID: 32914475
Multiply recurrent retroperitoneal liposarcoma.
Bagaria SP, Gabriel E, Mann GN
J Surg Oncol 2018 Jan;117(1):62-68. Epub 2017 Dec 19 doi: 10.1002/jso.24929. PMID: 29266232
Retroperitoneal sarcomas.
Francis IR, Cohan RH, Varma DG, Sondak VK
Cancer Imaging 2005 Aug 23;5(1):89-94. doi: 10.1102/1470-7330.2005.0019. PMID: 16154826Free PMC Article

Therapy

Preoperative Radiotherapy in Patients With Primary Retroperitoneal Sarcoma: EORTC-62092 Trial (STRASS) Versus Off-trial (STREXIT) Results.
Callegaro D, Raut CP, Ajayi T, Strauss D, Bonvalot S, Ng D, Stoeckle E, Fairweather M, Rutkowski P, van Houdt WJ, Gelderblom H, Sangalli C, Hayes A, Honoré C, Gladdy RA, Fau M, Haas R, Tzanis D, Miah AB, Chung P, Baldini EH, Marreaud S, Litiere S, Swallow CJ, Gronchi A
Ann Surg 2023 Jul 1;278(1):127-134. Epub 2022 Jul 14 doi: 10.1097/SLA.0000000000005492. PMID: 35833413
Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial.
Lansu J, Bovée JVMG, Braam P, van Boven H, Flucke U, Bonenkamp JJ, Miah AB, Zaidi SH, Thway K, Bruland ØS, Baldini EH, Jebsen NL, Scholten AN, van den Ende PLA, Krol ADG, Ubbels JF, van der Hage JA, van Werkhoven E, Klomp HM, van der Graaf WTA, van Coevorden F, Schrage Y, van Houdt WJ, Haas RL
JAMA Oncol 2021 Jan 1;7(1):e205865. Epub 2021 Jan 21 doi: 10.1001/jamaoncol.2020.5865. PMID: 33180100Free PMC Article
Transoral laser resection of hypopharyngeal liposarcoma.
Savoie A, Lester S
Ann R Coll Surg Engl 2021 Jan;103(1):e1-e3. Epub 2020 Aug 21 doi: 10.1308/rcsann.2020.0179. PMID: 32820661Free PMC Article
Liposarcoma: Multimodality Management and Future Targeted Therapies.
Crago AM, Dickson MA
Surg Oncol Clin N Am 2016 Oct;25(4):761-73. Epub 2016 Jul 30 doi: 10.1016/j.soc.2016.05.007. PMID: 27591497Free PMC Article
Diagnosis and management of lipomatous tumors.
Dalal KM, Antonescu CR, Singer S
J Surg Oncol 2008 Mar 15;97(4):298-313. doi: 10.1002/jso.20975. PMID: 18286473

Prognosis

Multiply recurrent retroperitoneal liposarcoma.
Bagaria SP, Gabriel E, Mann GN
J Surg Oncol 2018 Jan;117(1):62-68. Epub 2017 Dec 19 doi: 10.1002/jso.24929. PMID: 29266232
Giant Retroperitoneal Sarcoma.
Hazen B, Cocieru A
J Gastrointest Surg 2017 Mar;21(3):602-603. Epub 2016 Sep 9 doi: 10.1007/s11605-016-3258-0. PMID: 27613734
Personalizing surgical margins in retroperitoneal sarcomas.
Callegaro D, Fiore M, Gronchi A
Expert Rev Anticancer Ther 2015 May;15(5):553-67. Epub 2015 Mar 23 doi: 10.1586/14737140.2015.1028375. PMID: 25797538
Management of recurrent retroperitoneal sarcoma.
Gyorki DE, Brennan MF
J Surg Oncol 2014 Jan;109(1):53-9. Epub 2013 Oct 24 doi: 10.1002/jso.23463. PMID: 24155163
Retroperitoneal sarcomas.
Francis IR, Cohan RH, Varma DG, Sondak VK
Cancer Imaging 2005 Aug 23;5(1):89-94. doi: 10.1102/1470-7330.2005.0019. PMID: 16154826Free PMC Article

Clinical prediction guides

Preoperative Radiotherapy in Patients With Primary Retroperitoneal Sarcoma: EORTC-62092 Trial (STRASS) Versus Off-trial (STREXIT) Results.
Callegaro D, Raut CP, Ajayi T, Strauss D, Bonvalot S, Ng D, Stoeckle E, Fairweather M, Rutkowski P, van Houdt WJ, Gelderblom H, Sangalli C, Hayes A, Honoré C, Gladdy RA, Fau M, Haas R, Tzanis D, Miah AB, Chung P, Baldini EH, Marreaud S, Litiere S, Swallow CJ, Gronchi A
Ann Surg 2023 Jul 1;278(1):127-134. Epub 2022 Jul 14 doi: 10.1097/SLA.0000000000005492. PMID: 35833413
Pelvic soft tissue sarcomas.
Sarre-Lazcano C, Dumitra S, Fiore M
Eur J Surg Oncol 2023 Jun;49(6):1102-1110. Epub 2022 Jun 4 doi: 10.1016/j.ejso.2022.06.003. PMID: 35725682
Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial.
Lansu J, Bovée JVMG, Braam P, van Boven H, Flucke U, Bonenkamp JJ, Miah AB, Zaidi SH, Thway K, Bruland ØS, Baldini EH, Jebsen NL, Scholten AN, van den Ende PLA, Krol ADG, Ubbels JF, van der Hage JA, van Werkhoven E, Klomp HM, van der Graaf WTA, van Coevorden F, Schrage Y, van Houdt WJ, Haas RL
JAMA Oncol 2021 Jan 1;7(1):e205865. Epub 2021 Jan 21 doi: 10.1001/jamaoncol.2020.5865. PMID: 33180100Free PMC Article
Multiply recurrent retroperitoneal liposarcoma.
Bagaria SP, Gabriel E, Mann GN
J Surg Oncol 2018 Jan;117(1):62-68. Epub 2017 Dec 19 doi: 10.1002/jso.24929. PMID: 29266232
Management of recurrent retroperitoneal sarcoma.
Gyorki DE, Brennan MF
J Surg Oncol 2014 Jan;109(1):53-9. Epub 2013 Oct 24 doi: 10.1002/jso.23463. PMID: 24155163

Recent systematic reviews

Soft tissue sarcomas of the buttock: A systematic review and meta-analysis.
Sacco R, Lalevée M, Pellegrino P, Ferro A, Yasmine B, André G, Matthieu G, Hamza A, Piana R, Dujardin F
Surg Oncol 2022 Dec;45:101883. Epub 2022 Nov 7 doi: 10.1016/j.suronc.2022.101883. PMID: 36371906
Surgical management of truncal and extremities atypical lipomatous tumors/well-differentiated liposarcoma: A systematic review of the literature.
Choi KY, Jost E, Mack L, Bouchard-Fortier A
Am J Surg 2020 May;219(5):823-827. Epub 2020 Jan 28 doi: 10.1016/j.amjsurg.2020.01.046. PMID: 32029218
Laparoscopic approach to an incidentally found pelvic retroperitoneal liposarcoma: Case report and review.
Mandato VD, Mastrofilippo V, De Marco L, Aguzzoli L
Medicine (Baltimore) 2019 Apr;98(15):e15184. doi: 10.1097/MD.0000000000015184. PMID: 30985710Free PMC Article
Isolated Limb Perfusion and Infusion for Extremity Soft Tissue Sarcoma: A Contemporary Systematic Review and Meta-Analysis.
Neuwirth MG, Song Y, Sinnamon AJ, Fraker DL, Zager JS, Karakousis GC
Ann Surg Oncol 2017 Dec;24(13):3803-3810. Epub 2017 Oct 11 doi: 10.1245/s10434-017-6109-7. PMID: 29022281
Liposarcoma of Hypopharynx and Esophagus: a Unique Entity?
Riva G, Sensini M, Corvino A, Garzaro M, Pecorari G
J Gastrointest Cancer 2016 Jun;47(2):135-42. doi: 10.1007/s12029-016-9808-6. PMID: 26875081

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