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Locally Advanced Unresectable Prostate Adenocarcinoma

MedGen UID:
1658517
•Concept ID:
C4744717
•
Neoplastic Process

Definition

A prostatic adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes and is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Unresectable Prostate Adenocarcinoma

Recent clinical studies

Etiology

Implementing a comprehensive translational oncology platform: from molecular testing to actionability.
Mitri ZI, Parmar S, Johnson B, Kolodzie A, Keck JM, Morris M, Guimaraes AR, Beckett BR, Borate U, Lopez CD, Kemmer KA, Alumkal JJ, Beer TM, Corless CL, Mills GB, Gray JW, Bergan RC
J Transl Med 2018 Dec 14;16(1):358. doi: 10.1186/s12967-018-1733-y. PMID: 30551737Free PMC Article
A multicentre phase II trial of cabazitaxel in patients with advanced non-small-cell lung cancer progressing after docetaxel-based chemotherapy.
Kotsakis A, Matikas A, Koinis F, Kentepozidis N, Varthalitis II, Karavassilis V, Samantas E, Katsaounis P, Dermitzaki EK, Hatzidaki D, Mavroudis D, Georgoulias V
Br J Cancer 2016 Sep 27;115(7):784-8. Epub 2016 Sep 8 doi: 10.1038/bjc.2016.281. PMID: 27607471Free PMC Article
Addition of an induction regimen of antiangiogenesis and antitumor immunity to standard chemotherapy improves survival in advanced malignancies.
Lasalvia-Prisco E, Goldschmidt P, Galmarini F, Cucchi S, Vázquez J, Aghazarian M, Lasalvia-Galante E, Golomar W, Gordon W
Med Oncol 2012 Dec;29(5):3626-33. Epub 2012 Jul 19 doi: 10.1007/s12032-012-0301-1. PMID: 22810591Free PMC Article

Diagnosis

Implementing a comprehensive translational oncology platform: from molecular testing to actionability.
Mitri ZI, Parmar S, Johnson B, Kolodzie A, Keck JM, Morris M, Guimaraes AR, Beckett BR, Borate U, Lopez CD, Kemmer KA, Alumkal JJ, Beer TM, Corless CL, Mills GB, Gray JW, Bergan RC
J Transl Med 2018 Dec 14;16(1):358. doi: 10.1186/s12967-018-1733-y. PMID: 30551737Free PMC Article

Therapy

Implementing a comprehensive translational oncology platform: from molecular testing to actionability.
Mitri ZI, Parmar S, Johnson B, Kolodzie A, Keck JM, Morris M, Guimaraes AR, Beckett BR, Borate U, Lopez CD, Kemmer KA, Alumkal JJ, Beer TM, Corless CL, Mills GB, Gray JW, Bergan RC
J Transl Med 2018 Dec 14;16(1):358. doi: 10.1186/s12967-018-1733-y. PMID: 30551737Free PMC Article
A multicentre phase II trial of cabazitaxel in patients with advanced non-small-cell lung cancer progressing after docetaxel-based chemotherapy.
Kotsakis A, Matikas A, Koinis F, Kentepozidis N, Varthalitis II, Karavassilis V, Samantas E, Katsaounis P, Dermitzaki EK, Hatzidaki D, Mavroudis D, Georgoulias V
Br J Cancer 2016 Sep 27;115(7):784-8. Epub 2016 Sep 8 doi: 10.1038/bjc.2016.281. PMID: 27607471Free PMC Article
Addition of an induction regimen of antiangiogenesis and antitumor immunity to standard chemotherapy improves survival in advanced malignancies.
Lasalvia-Prisco E, Goldschmidt P, Galmarini F, Cucchi S, Vázquez J, Aghazarian M, Lasalvia-Galante E, Golomar W, Gordon W
Med Oncol 2012 Dec;29(5):3626-33. Epub 2012 Jul 19 doi: 10.1007/s12032-012-0301-1. PMID: 22810591Free PMC Article
Present status of fast neutron therapy in Asian countries.
Tsunemoto H, Yoo SY
Bull Cancer Radiother 1996;83 Suppl:93s-100s. doi: 10.1016/0924-4212(96)84891-2. PMID: 8949758
Pion radiotherapy at LAMPF.
Bush SE, Smith AR, Zink S
Int J Radiat Oncol Biol Phys 1982 Dec;8(12):2181-6. doi: 10.1016/0360-3016(82)90567-3. PMID: 6298158

Prognosis

Implementing a comprehensive translational oncology platform: from molecular testing to actionability.
Mitri ZI, Parmar S, Johnson B, Kolodzie A, Keck JM, Morris M, Guimaraes AR, Beckett BR, Borate U, Lopez CD, Kemmer KA, Alumkal JJ, Beer TM, Corless CL, Mills GB, Gray JW, Bergan RC
J Transl Med 2018 Dec 14;16(1):358. doi: 10.1186/s12967-018-1733-y. PMID: 30551737Free PMC Article

Clinical prediction guides

Addition of an induction regimen of antiangiogenesis and antitumor immunity to standard chemotherapy improves survival in advanced malignancies.
Lasalvia-Prisco E, Goldschmidt P, Galmarini F, Cucchi S, Vázquez J, Aghazarian M, Lasalvia-Galante E, Golomar W, Gordon W
Med Oncol 2012 Dec;29(5):3626-33. Epub 2012 Jul 19 doi: 10.1007/s12032-012-0301-1. PMID: 22810591Free PMC Article

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