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Locally Advanced Basal Cell Carcinoma

MedGen UID:
1652163
Concept ID:
C4745056
Neoplastic Process

Definition

A basal cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Basal Cell Carcinoma

Professional guidelines

PubMed

Moreiras Arias N, Vázquez Veiga H, Sánchez-Aguilar D
Med Clin (Barc) 2023 May 12;160(9):413-414. Epub 2023 Jan 14 doi: 10.1016/j.medcli.2022.12.007. PMID: 36646552
Villani A, Fabbrocini G, Scalvenzi M
Dermatol Ther 2022 Apr;35(4):e15348. Epub 2022 Feb 14 doi: 10.1111/dth.15348. PMID: 35102656Free PMC Article
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414

Recent clinical studies

Etiology

Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Fernández Orland A, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Yoo SY, Okoye E, Bassukas I, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Inocencio TJ, Chen CI, LaFontaine PR, Seebach F, Lowy I, Fury MG
J Am Acad Dermatol 2024 Feb;90(2):414-418. Epub 2023 Oct 14 doi: 10.1016/j.jaad.2023.08.111. PMID: 37839734
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Burness CB, Scott LJ
Target Oncol 2016 Apr;11(2):239-46. doi: 10.1007/s11523-016-0418-9. PMID: 26867946
Amici JM, Battistella M, Beylot-Barry M, Chatellier A, Dalac-Ra S, Dreno B, Falandry C, Froget N, Giacchero D, Grob JJ, Guerreschir P, Leccia MT, Malard O, Mortier L, Routier E, Stefan A, Stefan D, Stoebner PE, Basset-Seguin N
Eur J Dermatol 2015 Nov-Dec;25(6):586-94. doi: 10.1684/ejd.2015.2641. PMID: 26574792

Diagnosis

Idriss MH, Stull CM, Migden MR
Cancer Lett 2024 May 1;589:216821. Epub 2024 Mar 21 doi: 10.1016/j.canlet.2024.216821. PMID: 38521198
Mesti T, Sever M, Ocvirk J
Dermatology 2023;239(1):158-164. Epub 2022 Jul 27 doi: 10.1159/000525612. PMID: 35896082Free PMC Article
Gupta N, Ruiz ES
Drug Des Devel Ther 2022;16:183-190. Epub 2022 Jan 14 doi: 10.2147/DDDT.S325852. PMID: 35058688Free PMC Article
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Menjak IB, Petrella TM, Lee JW
J Oncol Pract 2018 Jun;14(6):389-391. Epub 2018 May 23 doi: 10.1200/JOP.18.00067. PMID: 29791246

Therapy

Moreiras Arias N, Vázquez Veiga H, Sánchez-Aguilar D
Med Clin (Barc) 2023 May 12;160(9):413-414. Epub 2023 Jan 14 doi: 10.1016/j.medcli.2022.12.007. PMID: 36646552
Pulido Prieto L, Esguerra Cantillo JA, Toquica Díaz NA, Ospina Delgado MA
Actas Dermosifiliogr 2023 Mar;114(3):264-267. Epub 2022 Oct 4 doi: 10.1016/j.ad.2021.10.020. PMID: 36206813
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Sekulic A, Migden MR, Oro AE, Dirix L, Lewis KD, Hainsworth JD, Solomon JA, Yoo S, Arron ST, Friedlander PA, Marmur E, Rudin CM, Chang AL, Low JA, Mackey HM, Yauch RL, Graham RA, Reddy JC, Hauschild A
N Engl J Med 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713. PMID: 22670903Free PMC Article

Prognosis

Idriss MH, Stull CM, Migden MR
Cancer Lett 2024 May 1;589:216821. Epub 2024 Mar 21 doi: 10.1016/j.canlet.2024.216821. PMID: 38521198
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Fernández Orland A, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Yoo SY, Okoye E, Bassukas I, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Inocencio TJ, Chen CI, LaFontaine PR, Seebach F, Lowy I, Fury MG
J Am Acad Dermatol 2024 Feb;90(2):414-418. Epub 2023 Oct 14 doi: 10.1016/j.jaad.2023.08.111. PMID: 37839734
Curragh DS, Huilgol SC, Selva D
Eye (Lond) 2021 Oct;35(10):2740-2745. Epub 2020 Nov 24 doi: 10.1038/s41433-020-01291-2. PMID: 33235336Free PMC Article
Paulsen JF, Øregaard JS, Nielsen AL, Gehl J, Venzo A
Acta Oncol 2016 Dec;55(12):1492-1494. Epub 2016 Jul 22 doi: 10.1080/0284186X.2016.1206212. PMID: 27448604
Reinders MG, Brinkhuizen T, Soetekouw PM, Kelleners-Smeets NW, Hamid MA, Mosterd K
Acta Derm Venereol 2015 May;95(5):618-9. doi: 10.2340/00015555-2020. PMID: 25425396

Clinical prediction guides

Herms F, Baroudjian B, Delyon J, Laly P, Tetu P, Lebbe C, Basset-Seguin N
Acta Derm Venereol 2022 May 23;102:adv00740. doi: 10.2340/actadv.v102.1995. PMID: 35604234Free PMC Article
Damsin T, Lebas E, Marchal N, Rorive A, Nikkels AF
Expert Rev Anticancer Ther 2022 Mar;22(3):243-248. Epub 2022 Feb 22 doi: 10.1080/14737140.2022.2043748. PMID: 35175882
Sekulic A, Yoo S, Kudchadkar R, Guillen J, Rogers G, Chang ALS, Guenthner S, Raskin B, Dawson K, Mun Y, Chu L, McKenna E, Lacouture M
PLoS One 2022;17(1):e0262151. Epub 2022 Jan 14 doi: 10.1371/journal.pone.0262151. PMID: 35030185Free PMC Article
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Khoo AB, Ali FR, Lear JT
Curr Opin Oncol 2016 Mar;28(2):180-4. doi: 10.1097/CCO.0000000000000259. PMID: 26780190

Recent systematic reviews

Patel A, Kim JS, Liss J, Howard L, Jung SH, Kheterpal M
Dermatol Ther 2021 Nov;34(6):e15172. Epub 2021 Oct 28 doi: 10.1111/dth.15172. PMID: 34676633
Jacobsen AA, Aldahan AS, Hughes OB, Shah VV, Strasswimmer J
JAMA Dermatol 2016 Jul 1;152(7):816-24. doi: 10.1001/jamadermatol.2016.0780. PMID: 27096888

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