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Metastatic malignant neoplasm in the brain

MedGen UID:
113095
Concept ID:
C0220650
Neoplastic Process
Synonyms: Brain Metastase; Brain Metastases
SNOMED CT: Secondary cancer of brain (94225005); Metastasis to brain (94225005); Secondary malignant neoplasm of brain (94225005); Metastatic malignant neoplasm to brain (94225005); Cancer metastatic to brain (94225005); Metastatic malignant neoplasm of brain (94225005)
 
Monarch Initiative: MONDO:1040026

Definition

A malignant neoplasm that has spread to the brain from another anatomic site or system. The majority are carcinomas (usually lung or breast carcinomas). [from NCI]

Professional guidelines

PubMed

Czarnywojtek A, Borowska M, Dyrka K, Van Gool S, Sawicka-Gutaj N, Moskal J, Kościński J, Graczyk P, Hałas T, Lewandowska AM, Czepczyński R, Ruchała M
Pharmacology 2023;108(5):423-431. Epub 2023 Jul 17 doi: 10.1159/000531319. PMID: 37459849
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BMJ 2021 Jul 14;374:n1560. doi: 10.1136/bmj.n1560. PMID: 34261630
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Recent clinical studies

Etiology

Suarez-Meade P, Marenco-Hillembrand L, Sherman WJ
Curr Oncol Rep 2022 Aug;24(8):975-984. Epub 2022 Mar 30 doi: 10.1007/s11912-022-01259-3. PMID: 35353348
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Lancet 2018 Aug 4;392(10145):432-446. Epub 2018 Jul 27 doi: 10.1016/S0140-6736(18)30990-5. PMID: 30060998
McNeill KA
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Wells EM, Packer RJ
Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):373-96. doi: 10.1212/01.CON.0000464176.96311.d1. PMID: 25837902

Diagnosis

Taylor LP, McGranahan TM, Venur VA
Semin Neurol 2023 Dec;43(6):808-809. Epub 2023 Dec 14 doi: 10.1055/s-0043-1776767. PMID: 38096848
Lah TT, Novak M, Breznik B
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Nat Rev Dis Primers 2019 Jan 17;5(1):6. doi: 10.1038/s41572-019-0061-8. PMID: 30655539
Wen PY, Reardon DA
Nat Rev Neurol 2016 Feb;12(2):69-70. Epub 2016 Jan 18 doi: 10.1038/nrneurol.2015.242. PMID: 26782337
Pollack IF
N Engl J Med 1994 Dec 1;331(22):1500-7. doi: 10.1056/NEJM199412013312207. PMID: 7969301

Therapy

Rominiyi O, Vanderlinden A, Clenton SJ, Bridgewater C, Al-Tamimi Y, Collis SJ
Br J Cancer 2021 Feb;124(4):697-709. Epub 2020 Nov 4 doi: 10.1038/s41416-020-01136-5. PMID: 33144698Free PMC Article
Hollon TC, Pandian B, Adapa AR, Urias E, Save AV, Khalsa SSS, Eichberg DG, D'Amico RS, Farooq ZU, Lewis S, Petridis PD, Marie T, Shah AH, Garton HJL, Maher CO, Heth JA, McKean EL, Sullivan SE, Hervey-Jumper SL, Patil PG, Thompson BG, Sagher O, McKhann GM 2nd, Komotar RJ, Ivan ME, Snuderl M, Otten ML, Johnson TD, Sisti MB, Bruce JN, Muraszko KM, Trautman J, Freudiger CW, Canoll P, Lee H, Camelo-Piragua S, Orringer DA
Nat Med 2020 Jan;26(1):52-58. Epub 2020 Jan 6 doi: 10.1038/s41591-019-0715-9. PMID: 31907460Free PMC Article
Wen PY, Reardon DA
Nat Rev Neurol 2016 Feb;12(2):69-70. Epub 2016 Jan 18 doi: 10.1038/nrneurol.2015.242. PMID: 26782337
Lin NU, Lee EQ, Aoyama H, Barani IJ, Barboriak DP, Baumert BG, Bendszus M, Brown PD, Camidge DR, Chang SM, Dancey J, de Vries EG, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wen PY; Response Assessment in Neuro-Oncology (RANO) group
Lancet Oncol 2015 Jun;16(6):e270-8. Epub 2015 May 27 doi: 10.1016/S1470-2045(15)70057-4. PMID: 26065612
Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, Macdonald JS, Young B
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Prognosis

Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2019 Nov 1;21(Suppl 5):v1-v100. doi: 10.1093/neuonc/noz150. PMID: 31675094Free PMC Article
Witthayanuwat S, Pesee M, Supaadirek C, Supakalin N, Thamronganantasakul K, Krusun S
Asian Pac J Cancer Prev 2018 Sep 26;19(9):2613-2617. doi: 10.22034/APJCP.2018.19.9.2613. PMID: 30256068Free PMC Article
Cagney DN, Martin AM, Catalano PJ, Redig AJ, Lin NU, Lee EQ, Wen PY, Dunn IF, Bi WL, Weiss SE, Haas-Kogan DA, Alexander BM, Aizer AA
Neuro Oncol 2017 Oct 19;19(11):1511-1521. doi: 10.1093/neuonc/nox077. PMID: 28444227Free PMC Article
Rose D, Papa A, Tomao S, Greco E, Zacharias J
J Card Surg 2016 May;31(5):289-93. Epub 2016 Mar 20 doi: 10.1111/jocs.12727. PMID: 26996368
Sanford RA, Gajjar A
Clin Neurosurg 1997;44:559-70. PMID: 10080027

Clinical prediction guides

Harlianto NI
Radiol Imaging Cancer 2024 Sep;6(5):e249016. doi: 10.1148/rycan.249016. PMID: 39177471Free PMC Article
Tyagi A, Wu SY, Watabe K
Cancer Lett 2022 Jul 28;539:215713. Epub 2022 May 2 doi: 10.1016/j.canlet.2022.215713. PMID: 35513201Free PMC Article
Li G, Wu F, Zeng F, Zhai Y, Feng Y, Chang Y, Wang D, Jiang T, Zhang W
CNS Neurosci Ther 2021 Feb;27(2):186-195. Epub 2020 Oct 16 doi: 10.1111/cns.13464. PMID: 33063446Free PMC Article
Suh JH, Kotecha R, Chao ST, Ahluwalia MS, Sahgal A, Chang EL
Nat Rev Clin Oncol 2020 May;17(5):279-299. Epub 2020 Feb 20 doi: 10.1038/s41571-019-0320-3. PMID: 32080373
Davis ME
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Recent systematic reviews

Coronatto LH, Formentin C
Rev Assoc Med Bras (1992) 2024;70(suppl 1):e2024S122. Epub 2024 Jun 7 doi: 10.1590/1806-9282.2024S122. PMID: 38865542Free PMC Article
Li Y, Liu Y, Liang Y, Wei R, Zhang W, Yao W, Luo S, Pang X, Wang Y, Jiang X, Lai S, Yang R
Eur Radiol 2022 Nov;32(11):8039-8051. Epub 2022 May 19 doi: 10.1007/s00330-022-08828-x. PMID: 35587827
Gondi V, Bauman G, Bradfield L, Burri SH, Cabrera AR, Cunningham DA, Eaton BR, Hattangadi-Gluth JA, Kim MM, Kotecha R, Kraemer L, Li J, Nagpal S, Rusthoven CG, Suh JH, Tomé WA, Wang TJC, Zimmer AS, Ziu M, Brown PD
Pract Radiat Oncol 2022 Jul-Aug;12(4):265-282. Epub 2022 May 6 doi: 10.1016/j.prro.2022.02.003. PMID: 35534352
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Rosenfelder N, Khoo V
BMJ Clin Evid 2011 Jul 26;2011 PMID: 21791125Free PMC Article

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