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Allergy to peanut

MedGen UID:
108242
•Concept ID:
C0559470
•
Disease or Syndrome
Synonyms: Allergies, Peanut; Allergy, Peanut; Groundnut Hypersensitivity; Hypersensitivity, Groundnut; Hypersensitivity, Peanut; Peanut Allergies; Peanut Allergy; Peanut Hypersensitivity
SNOMED CT: Allergy to peanuts (91935009); Allergy to peanut (91935009)

Definition

Allergic reaction to peanuts that is triggered by the immune system. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAllergy to peanut

Professional guidelines

PubMed

Evaluation and Modification of a Shared Decision-Making Tool for Peanut Allergy Management.
Anagnostou A, Yaworsky A, Brova M, Ibrahim N, Kakked S, Spite S, Duluc L, Shields AL, Lee T, Leonard S, Przywara K, Smith A
Curr Allergy Asthma Rep 2024 Jun;24(6):303-315. Epub 2024 Apr 19 doi: 10.1007/s11882-024-01146-w. PMID: 38639896
Effectiveness of Clinical Decision Support Tools on Pediatrician Adherence to Peanut Allergy Prevention Guidelines.
Bilaver LA, Martusiewicz MN, Jiang J, Gupta RS
JAMA Pediatr 2019 Dec 1;173(12):1198-1199. doi: 10.1001/jamapediatrics.2019.3360. PMID: 31609434Free PMC Article
Oral immunotherapy for the treatment of peanut allergy: systematic review of six case series studies.
Sheikh A, Nurmatov U, Venderbosch I, Bischoff E
Prim Care Respir J 2012 Mar;21(1):41-9. doi: 10.4104/pcrj.2011.00071. PMID: 21938350Free PMC Article

Recent clinical studies

Etiology

Moving Past "Avoid All Nuts": Individualizing Management of Children with Peanut/Tree Nut Allergies.
Schroer B, Bjelac J
Immunol Allergy Clin North Am 2019 Nov;39(4):495-506. doi: 10.1016/j.iac.2019.07.004. PMID: 31563184
GRADE-ing the Benefit/Risk Equation in Food Immunotherapy.
Duca B, Patel N, Turner PJ
Curr Allergy Asthma Rep 2019 Apr 25;19(6):30. doi: 10.1007/s11882-019-0862-6. PMID: 31025125Free PMC Article
Epidemiology of Food Allergy.
Dunlop JH, Keet CA
Immunol Allergy Clin North Am 2018 Feb;38(1):13-25. Epub 2017 Oct 26 doi: 10.1016/j.iac.2017.09.002. PMID: 29132669
The role of environmental exposure to peanut in the development of clinical allergy to peanut.
Foong RX, Brough H
Clin Exp Allergy 2017 Oct;47(10):1232-1238. Epub 2017 Sep 15 doi: 10.1111/cea.12992. PMID: 28779526
Allergy to peanut oil--clinically relevant?
Ring J, Möhrenschlager M
J Eur Acad Dermatol Venereol 2007 Apr;21(4):452-5. doi: 10.1111/j.1468-3083.2006.02133.x. PMID: 17373969

Diagnosis

From Allergen Molecules to Molecular Immunotherapy of Nut Allergy: A Hard Nut to Crack.
Fuhrmann V, Huang HJ, Akarsu A, Shilovskiy I, Elisyutina O, Khaitov M, van Hage M, Linhart B, Focke-Tejkl M, Valenta R, Sekerel BE
Front Immunol 2021;12:742732. Epub 2021 Sep 23 doi: 10.3389/fimmu.2021.742732. PMID: 34630424Free PMC Article
Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life.
Neeland MR, Andorf S, Manohar M, Dunham D, Lyu SC, Dang TD, Peters RL, Perrett KP, Tang MLK, Saffery R, Koplin JJ, Nadeau KC
Nat Commun 2020 Feb 27;11(1):1091. doi: 10.1038/s41467-020-14919-4. PMID: 32107388Free PMC Article
Moving Past "Avoid All Nuts": Individualizing Management of Children with Peanut/Tree Nut Allergies.
Schroer B, Bjelac J
Immunol Allergy Clin North Am 2019 Nov;39(4):495-506. doi: 10.1016/j.iac.2019.07.004. PMID: 31563184
Peanut and tree nut allergy.
Cox A, Sicherer SH
Chem Immunol Allergy 2015;101:131-44. Epub 2015 May 21 doi: 10.1159/000375417. PMID: 26022873
Allergy to peanut lipid transfer protein (LTP): frequency and cross-reactivity between peanut and peach LTP.
Romano A, Fernandez-Rivas M, Caringi M, Amato S, Mistrello G, Asero R
Eur Ann Allergy Clin Immunol 2009 Aug;41(4):106-11. PMID: 19877562

Therapy

Moving Past "Avoid All Nuts": Individualizing Management of Children with Peanut/Tree Nut Allergies.
Schroer B, Bjelac J
Immunol Allergy Clin North Am 2019 Nov;39(4):495-506. doi: 10.1016/j.iac.2019.07.004. PMID: 31563184
The role of environmental exposure to peanut in the development of clinical allergy to peanut.
Foong RX, Brough H
Clin Exp Allergy 2017 Oct;47(10):1232-1238. Epub 2017 Sep 15 doi: 10.1111/cea.12992. PMID: 28779526
Peanut and tree nut allergy.
Cox A, Sicherer SH
Chem Immunol Allergy 2015;101:131-44. Epub 2015 May 21 doi: 10.1159/000375417. PMID: 26022873
Allergy to peanut oil--clinically relevant?
Ring J, Möhrenschlager M
J Eur Acad Dermatol Venereol 2007 Apr;21(4):452-5. doi: 10.1111/j.1468-3083.2006.02133.x. PMID: 17373969
Kiss-induced allergy to peanut.
Wüthrich B, Däscher M, Borelli S
Allergy 2001 Sep;56(9):913. doi: 10.1034/j.1398-9995.2001.00302.x. PMID: 11551258

Prognosis

Food Allergy in Infants With Atopic Dermatitis: Limitations of Food-Specific IgE Measurements.
Spergel JM, Boguniewicz M, Schneider L, Hanifin JM, Paller AS, Eichenfield LF
Pediatrics 2015 Dec;136(6):e1530-8. doi: 10.1542/peds.2015-1444. PMID: 26598458
Ethnic differences in peanut allergy patterns in South African children with atopic dermatitis.
Gray CL, Levin ME, du Toit G
Pediatr Allergy Immunol 2015 Dec;26(8):721-30. Epub 2015 Sep 28 doi: 10.1111/pai.12459. PMID: 26267015
Allergy to peanut lipid transfer protein (LTP): frequency and cross-reactivity between peanut and peach LTP.
Romano A, Fernandez-Rivas M, Caringi M, Amato S, Mistrello G, Asero R
Eur Ann Allergy Clin Immunol 2009 Aug;41(4):106-11. PMID: 19877562
Diagnosing peanut allergy with skin prick and specific IgE testing.
Roberts G, Lack G
J Allergy Clin Immunol 2005 Jun;115(6):1291-6. doi: 10.1016/j.jaci.2005.02.038. PMID: 15940149

Clinical prediction guides

Fecal Microbiome and Food Allergy in Pediatric Atopic Dermatitis: A Cross-Sectional Pilot Study.
Fieten KB, Totté JEE, Levin E, Reyman M, Meijer Y, Knulst A, Schuren F, Pasmans SGMA
Int Arch Allergy Immunol 2018;175(1-2):77-84. Epub 2018 Jan 25 doi: 10.1159/000484897. PMID: 29393195
Clinical allergy to hazelnut and peanut: identification of T cell cross-reactive allergens.
Glaspole IN, de Leon MP, Prickett SR, O'Hehir RE, Rolland JM
Int Arch Allergy Immunol 2011;155(4):345-54. Epub 2011 Feb 22 doi: 10.1159/000321268. PMID: 21346364
Allergy to peanut lipid transfer protein (LTP): frequency and cross-reactivity between peanut and peach LTP.
Romano A, Fernandez-Rivas M, Caringi M, Amato S, Mistrello G, Asero R
Eur Ann Allergy Clin Immunol 2009 Aug;41(4):106-11. PMID: 19877562
Allergy to peanut oil--clinically relevant?
Ring J, Möhrenschlager M
J Eur Acad Dermatol Venereol 2007 Apr;21(4):452-5. doi: 10.1111/j.1468-3083.2006.02133.x. PMID: 17373969
Diagnosing peanut allergy with skin prick and specific IgE testing.
Roberts G, Lack G
J Allergy Clin Immunol 2005 Jun;115(6):1291-6. doi: 10.1016/j.jaci.2005.02.038. PMID: 15940149

Recent systematic reviews

Prevalence of common food allergies in Europe: a systematic review and meta-analysis.
Nwaru BI, Hickstein L, Panesar SS, Roberts G, Muraro A, Sheikh A; EAACI Food Allergy and Anaphylaxis Guidelines Group
Allergy 2014 Aug;69(8):992-1007. Epub 2014 May 10 doi: 10.1111/all.12423. PMID: 24816523

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