CADM3 cell adhesion molecule 3
Gene ID: 57863, updated on 4-Jan-2025Gene type: protein coding
Also known as: BIgR; NECL1; TSLL1; CMT2FF; IGSF4B; Necl-1; synCAM3
- See all available tests in GTR for this gene
- Go to complete Gene record for CADM3
- Go to Variation Viewer for CADM3 variants
Summary
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation. GeneReviews: Not available | |
| Charcot-Marie-Tooth disease, axonal, type 2FF | See labs |
| Genome-wide association with select biomarker traits in the Framingham Heart Study. GeneReviews: Not available |
Genomic context
- Location:
- 1q23.2
- Sequence:
- Chromosome: 1; NC_000001.11 (159171615..159203313)
- Total number of exons:
- 12
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for CADM3 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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