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Sample GSM92538 Query DataSets for GSM92538
Status Public on Apr 01, 2006
Title PC xenograft PC295 after castration replicate_1
Sample type RNA
 
Channel 1
Source name xenograft
Organism Homo sapiens
Characteristics Androgen-dependent xenograft, androgen receptor expressing, 9 days after castration of male host mouse.
Extracted molecule total RNA
Label Cy3
 
Channel 2
Source name common reference of 13 cell lines
Organism Homo sapiens
Characteristics 13 cell lines that originated from prostate cancer (Du145 and LNCaP), breast (MCF7 and ZR75.1), bone (MG63), colon (HT29), endothelium (Ea-hy926), ovary (A2780), skin (SK-MEL-28), B-cell leukemia (Raji), T-cell lymphoblastoma (Jurkat) and fibroblasts (N92-19N and N92-19T).
Extracted molecule total RNA
Label Cy5
 
 
Description The prostate cancer xenografts have been described by van Weerden and Romijn (Prostate 2000; 43:263-271). The xenografts were serially passaged subcutaneously in both shoulders of male Swiss nude mice.
Data processing Normalization was performed using R-routines (Lowess method; http://cmfdb.nki.nl/). All spots with an R-value below 3 or with an average intensity less than 0.4 of the median spot intensity per subarray were considered to be insufficiently reliable and were excluded from the data analysis.
 
Submission date Jan 13, 2006
Last update date Jan 23, 2006
Contact name Peter Hendriksen
E-mail(s) [email protected]
Organization name Wageningen University & Research
Department RIKILT
Street address Akkermaalsbos 2
City Wageningen
ZIP/Postal code 6708 WB
Country Netherlands
 
Platform ID GPL3349
Series (1)
GSE4084 Human prostate cancer xenografts on intact mice or after castration.

Data table header descriptions
ID_REF spot number
VALUE normalized log2 ratio of xenograft / common reference
CH1_SIG_MEAN Mean signal intensity of the spot of channel 1
CH1_BKD_MEAN Mean intensity of the background of channel 1
CH2_SIG_MEAN Mean signal intensity of the spot of channel 2
CH2_BKD_MEAN Mean intensity of the background of channel 2

Data table
ID_REF VALUE CH1_SIG_MEAN CH1_BKD_MEAN CH2_SIG_MEAN CH2_BKD_MEAN
1 -0.26 6327.155556 3371.554717 8174.535032 2868.559671
2 -0.26 3818.690476 3304.025253 3590.391753 2715.644909
3 0.27 6889.653846 3311.091549 7256.688742 2801.044983
4 0.11 4580.257426 3287.588448 4549.378151 2768.501931
5 3256.854839 3222.197279 2701.483871 2661.442177
6 3301.958621 3228.226044 2711.531034 2646.04914
7 3261.376147 3239.190332 2636.440367 2647.280967
8 3290.770642 3262.167116 2750.220183 2711.876011
9 3214.954128 3264.309859 2648.972477 2708.807512
10 3258.041451 3250.855019 2713.378238 2666.572491
11 3289.467742 3247.536 2736.903226 2696.208
12 3325.082569 3272.598187 2754.788991 2712.205438
13 3267.137615 3271.060519 2729.357798 2683.579251
14 3257.903226 3258.566524 2714.854839 2714.482759
15 3332.972477 3262.407767 2767.082569 2707.68932
16 3334.623853 3268.983923 2747.449541 2692.797428
17 3274.481481 3270.560976 2716.027778 2676.538776
18 3251.59633 3254.974504 2714.477064 2712.283286
19 3267.129534 3269.048327 2715.015544 2680.572491
20 3247.080645 3255.905455 2704.758065 2675.178182

Total number of rows: 19185

Table truncated, full table size 1039 Kbytes.




Supplementary data files not provided
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