|
| Status |
Public on Dec 10, 2018 |
| Title |
MMTV-Neu.176661.Untreated.aCGH |
| Sample type |
genomic |
| |
|
| Channel 1 |
| Source name |
DNA reference - UCSC mm7/NCBI release 35 (August 2005)
|
| Organism |
Mus musculus |
| Characteristics |
characteristics: reference: DNA reference
|
| Treatment protocol |
4 different treatments: Untreated, 3 week treatment, 6 week treatment, and Entinostat Progression
|
| Extracted molecule |
genomic DNA |
| Extraction protocol |
genomic DNA isolated using Dneasy kit (Qiagen)
|
| Label |
Cy3
|
| Label protocol |
labeled according to the direct incorporation method (Agilent)
|
| |
|
| Channel 2 |
| Source name |
MMTV-Neu.176661.Untreated.aCGH
|
| Organism |
Mus musculus |
| Characteristics |
cell line: MMTV-Neu
treatment: Untreated
|
| Treatment protocol |
4 different treatments: Untreated, 3 week treatment, 6 week treatment, and Entinostat Progression
|
| Extracted molecule |
genomic DNA |
| Extraction protocol |
genomic DNA isolated using Dneasy kit (Qiagen)
|
| Label |
Cy5
|
| Label protocol |
labeled according to the direct incorporation method (Agilent)
|
| |
|
| |
| Hybridization protocol |
hybridized to Agilent 244k CGH arrays (model G4415A)
|
| Scan protocol |
scanned on Agilent scanner (model G2505B)
|
| Description |
aCGH
|
| Data processing |
Data for both channels were Lowess-normalized and then log(2) ratio was taken
|
| |
|
| Submission date |
Aug 19, 2018 |
| Last update date |
Dec 10, 2018 |
| Contact name |
Charles M. Perou |
| E-mail(s) |
[email protected]
|
| Organization name |
University of North Carolina at Chapel Hill
|
| Department |
Professor of Genetics, and Pathology & Laboratory Medicine; Lineberger Comprehensive Cancer Center
|
| Street address |
12-044 Lineberger Comprehensive Cancer Center CB# 7295
|
| City |
Chapel Hill |
| State/province |
NC |
| ZIP/Postal code |
27599-7264 |
| Country |
USA |
| |
|
| Platform ID |
GPL4092 |
| Series (2) |
| GSE118743 |
Identification of Jun loss that promotes resistance to HDAC inhibitor Entinostat through Myc signaling in Luminal breast cancer [CGH] |
| GSE118744 |
Identification of Jun loss that promotes resistance to HDAC inhibitor Entinostat through Myc signaling in Luminal breast cancer |
|
