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Sample GSM247016 Query DataSets for GSM247016
Status Public on Dec 06, 2007
Title MPR006845
Sample type RNA
 
Source name tumor sample
Organism Homo sapiens
Characteristics studyCode = 39
treatment = Dex
sex = Male
race = Black
Age_at_Randomization = 54
Date_of_Randomization = 10-Feb-03
Myeloma_Measure = IGG
PGx_Response = NC
PGx_Responder = NR
PGx_Progression(0=No,1=Yes) = 1
PGx_Days_To_Progression = 148
Days_Survived_From_Randomization = 844
albumin = 46
C_Reactive_Protein = 4
Beta2_Microglobulin = 3.4
Number_of_Prior_Lines = 2
meanMyelScore = 67.3
Mayo_Clinic_ProliferativeIndex = 0.776351996
TC_Class_2006 = D1
Treatment protocol samples were subject to a rapid enrichment procedure (see details in http://bloodjournal.hematologylibrary.org/cgi/content/full/109/8/3177) and tumor cell pellet was frozen
Growth protocol tumor samples were collected during patient screening period prior to entry into clinical trials for the treatment of multiple myeloma
Extracted molecule total RNA
Extraction protocol Total RNA was isolated using Qiagen RNAeasy kit
Label biotin
Label protocol A standard T7 based amplification protocol (Affymetrix) was used to convert 2.0 microgram of RNA to biotinylated cRNA.
 
Hybridization protocol cRNA for each sample was hybridized in triplicate to the U133A/B array. Data represent median of replicates that passed array QC.
Scan protocol Microarrays were scanned with GeneArray 3000 scaner (Affymetrix).
Description Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
Data processing Dataprocessing used Affymetrix MAS5.0.
 
Submission date Dec 04, 2007
Last update date Dec 05, 2007
Contact name George Mulligan
Organization name Millennium Pharmaceuticals
Department Clinical Development
Street address 35 Landsdowne Stree
City Cambridge
State/province MA
ZIP/Postal code 02139
Country USA
 
Platform ID GPL97
Series (1)
GSE9782 Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

Data table header descriptions
ID_REF
VALUE MAS5 signal intensity

Data table
ID_REF VALUE
200000_s_at 901.418
200001_at 1854.82
200002_at 30766.4
200003_s_at 33142.2
200004_at 3453.75
200005_at 3659.3
200006_at 4631.01
200007_at 3646.09
200008_s_at 987.97
200009_at 2323.63
200010_at 13811
200011_s_at 626.577
200012_x_at 39200.7
200013_at 22616
200014_s_at 833.506
200015_s_at 1094.33
200016_x_at 11753.3
200017_at 11939.8
200018_at 34214
200019_s_at 22706.3

Total number of rows: 22645

Table truncated, full table size 403 Kbytes.




Supplementary data files not provided
Processed data included within Sample table

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