|
| Status |
Public on Jul 23, 2021 |
| Title |
Lin28a and Lin28b are required for lung branching morphogenesis and epithelial cell differentiation via coordination of signaling pathway feedback loops in a let7-independent manner |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We examined the role of Lin28a and b during lung development and found dual loss led to defects in branching.
|
| |
|
| Overall design |
Double knockout of Lin28a and b using the epithelial specific cre, NKX2.1creERT
|
| |
|
| Contributor(s) |
Daley GQ, Osborne J, Han A |
| Citation(s) |
34289374 |
| |
| Submission date |
Jan 12, 2017 |
| Last update date |
Jul 23, 2021 |
| Contact name |
Areum Han |
| E-mail(s) |
[email protected]
|
| Organization name |
Boston Children's Hospital
|
| Lab |
Daley lab
|
| Street address |
Karp Family Building, 7th Floor. 300 Longwood Ave.
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA361148 |
| SRA |
SRP096661 |
