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| Status |
Public on Aug 28, 2018 |
| Title |
microRNA-seq of TPR50 Tau P301S Transgenic Mouse in different brain regions and time-points |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Purpose: The goal of this study was to assess miRNA expression changes in TPR50 Tau transgenic mice. The mice was backcrossed with 2 divergent mouse strains - DBA and FVB along with the parent C57BL6 strain. The resulting F1 hybrids were used for further analysis.
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| Overall design |
Brain samples from F1 hybrids were isolated and falsh frozen. RNA was isolated using miRNeasy kit and RNA-seq was performed using standard Illumina kit for small RNA sequencing
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| Contributor(s) |
Swarup V, Geschwind DH |
| Citation(s) |
30510257 |
| |
| Submission date |
Nov 17, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Vivek Swarup |
| E-mail(s) |
[email protected]
|
| Organization name |
University of California Irvine
|
| Department |
Neurobiology and Behavior
|
| Street address |
3400 Bio Sci 3
|
| City |
Irvine |
| State/province |
CALIFORNIA |
| ZIP/Postal code |
92697 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (276)
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| This SubSeries is part of SuperSeries: |
| GSE90696 |
Identification of evolutionary conserved gene networks that mediate neurodegenerative dementia |
|
| Relations |
| BioProject |
PRJNA354345 |
| SRA |
SRP093622 |
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