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Status |
Public on Feb 08, 2017 |
Title |
Impact of Visceral Fat Adiposity on Gene Expression Profile in Peripheral Blood Cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We profiled gene expression in peripheral blood cells from 17 obese patients by microarray analysis and revealed that visceral fat adiposity impact on gene expression profile in peripheral blood cells compared to subcutaneous fat accumulation.
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Overall design |
Obesity was defined as body mass index (BMI) greater than 25 kg/m2 according to the Japanese criteria. Visceral fat area (VFA) and subcutaneous fat area (SFA) were measured by computed tomography (CT) and determined in the cross-sectional slice at the umbilical level. Subjects with type 1 diabetes mellitus, malignant diseases, autoimmune diseases, and infectious diseases were excluded. Patients treated with anti-diabetic drugs were also excluded.
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Contributor(s) |
Obata Y, Maeda N, Nakamura S, Funahashi T, Matsubara K, Matsuzawa Y, Shimomura I |
Citation(s) |
27899146 |
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Submission date |
Aug 05, 2016 |
Last update date |
Jan 09, 2018 |
Contact name |
Norikazu Maeda |
Organization name |
Osaka University
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Department |
Graduate School of Medicine
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Lab |
Metabolic Medicine
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Street address |
2-2-B5
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City |
Suita |
State/province |
Osaka |
ZIP/Postal code |
565-0871 |
Country |
Japan |
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Platforms (1) |
GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
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Samples (17)
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Relations |
BioProject |
PRJNA337900 |