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| Status |
Public on Jun 13, 2017 |
| Title |
PBMC transcriptome profiles identifies potential candidate genes and functional networks controlling the innate and the adaptive immune response to PRRSV vaccine in Pietrain pig |
| Organism |
Sus scrofa |
| Experiment type |
Expression profiling by array
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| Summary |
In vivo microarray study of global gene expression changes in peripheral blood mononuclear cells (PBMCs) of Pietrain pigs during the stage of inatte immune and adaptive immune response to porcine reproductive and respiratory syndrome virus vaccination.
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| Overall design |
PBMCs samples collected at three time points (0, 1 and 28 d post ) from PRRSV vaccinated Pietrain pigs were subjected for hybridization of 9 arrays. Samples from each of time points were hybridized with three biological replications. To characterize the gene expression changes, we compared the PBMCs transcriptome profiles in two contrast pairs: day 1 post vaccination versus day 0 or just before vaccination (D1 vs. D0) and day 28 post vaccination versus day 0 or just before vaccination (D28 vs. D0).
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| Contributor(s) |
Islam A, Schellander K, Neuhoff C |
| Citation(s) |
28278192, 31536525 |
| |
| Submission date |
Jul 18, 2016 |
| Last update date |
Oct 08, 2019 |
| Contact name |
Chritiane Neuhoff |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Bonn
|
| Department |
Institute of Animal Science
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| Lab |
Animal Breeding and Husbandry group
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| Street address |
Endenicher Allee 15
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| City |
Bonn |
| State/province |
NRW |
| ZIP/Postal code |
53115 |
| Country |
Germany |
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| Platforms (2) |
| GPL16493 |
[PorGene-1_0-st] Porcine Gene 1.0 ST Array [transcript (gene) version] |
| GPL21514 |
[PorGene-1_0-st] Porcine Gene 1.0 ST Array [probe set (exon) version] |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA329532 |
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