|
| Status |
Public on Jul 25, 2016 |
| Title |
Transcriptomics response to miR-644 overexpression in three breast cancer cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The goal of the study is to investigate the effect of microRNA-644 overexpression by chemical mimics on gene expression in breast cancer cell lines. To this purpose control and microRNA-644 mimics are used to transfect MDA-MB-231 cells, SK-BR-3 cells, and MCF-7 cells respectively. Transcriptomics profiling was performed with Illumina HumanHT-12 V4.0 BeadChip microarray.
|
| |
|
| Overall design |
Three cell lines are treated with scramble microRNA mimic (control herein) and microRNA-644 mimic (miR-644 herein), with two replicates per condition. mRNA expression is compared between miR-644 and control treatment within each cell line, respectively.
|
| |
|
| Contributor(s) |
Uhlmann S, Zhang JD, Sahin Ö |
| Citation(s) |
27409664 |
| |
| Submission date |
May 31, 2016 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Jitao David Zhang |
| E-mail(s) |
[email protected]
|
| Phone |
+41616886251
|
| Organization name |
F. Hoffmann-La Roche
|
| Department |
Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel
|
| Lab |
Pharmaceutical Sciences
|
| Street address |
Grenzacherstrasse 124
|
| City |
Basel |
| ZIP/Postal code |
4070 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA323851 |
Less...
More...