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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Aug 22, 2016 |
| Title |
RIPK3 restricts myeloid leukemogenesis by promoting cell death and differentiation of leukemia initiating cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Examination of gene expression patterns in lineage negative FLT3-ITD– and pMIG-transduced BM cells via microarray study.
We performed a global mRNA profiling analysis of murine Lin– FLT3-ITD+ cells compared to empty-vector controls, purified 48h after transduction. We examined association patterns of FLT3-ITD and pMIG cells and identified a specific gene expression signature associated with FLT3-ITD signalling.
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| Overall design |
Total RNA obtained from isolated lineage negative BM cells subjected to 48h of FLT3-ITD signalling compared to empty vector control.
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| Contributor(s) |
Höckendorf U, Yabal M, Herold T, Munkhbaatar E, Rott S, Jilg S, Kauschinger J, Magnani G, Reisinger F, Heuser M, Kreipe H, Sotlar K, Engleitner T, Rad R, Weichert W, Peschel C, Ruland J, Heikenwalder M, Spiekermann K, Slotta J, Groß O, Jost PJ |
| Citation(s) |
27411587 |
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| Submission date |
Mar 09, 2016 |
| Last update date |
Nov 24, 2017 |
| Contact name |
Sebastian Mueller |
| E-mail(s) |
[email protected]
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| Organization name |
Klinikum rechts der Isar
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| Department |
Institut für Molekulare Onkologie und Funktionelle Genomik
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| Street address |
Ismaninger Strasse 22
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| City |
München |
| ZIP/Postal code |
81675 |
| Country |
Germany |
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| Platforms (1) |
| GPL17543 |
Illumina MouseWG-6 v2.0 R2 expression beadchip |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA314776 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE79040_Non-normalized_data.txt.gz |
898.6 Kb |
(ftp)(http) |
TXT |
| GSE79040_RAW.tar |
3.6 Mb |
(http)(custom) |
TAR (of IDAT) |
| Processed data included within Sample table |
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