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| Status |
Public on Jul 30, 2016 |
| Title |
Investigation of miRNA expression signatures in mTORC1 -stimulated osteoarthritis |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
To further explain pathology of mTORC1 -stimulated osteoarthritis, we have employed whole genome microarray expression profiling as a discovery platform to identify miRNAs which involved in development of mTORC1-stimulated osteoarthritis
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| Overall design |
We generated Col2a1-specific deletion of Tsc1 mice. mTORC1 induced miRNAs expression in development of osteoarthritis was measured at eight weeks after birth. Independent experiments were performed using knee joint cartilage from Col2a1Tsc1KO and control mice.
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| Contributor(s) |
Bai X, Wang H |
| Citation missing |
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| |
| Submission date |
Jul 29, 2015 |
| Last update date |
Sep 27, 2016 |
| Contact name |
hua wang |
| E-mail(s) |
[email protected]
|
| Organization name |
southern medical university
|
| Department |
cell biology
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| Street address |
gongzhou dadao bei
|
| City |
guanghzou |
| State/province |
guangdong |
| ZIP/Postal code |
510515 |
| Country |
China |
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| Platforms (1) |
| GPL17912 |
Agilent-046065 Mouse_miRNA_V19.0_Microarray (miRNA ID version) |
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| Samples (2) |
| GSM1835358 |
control_knee joint cartilage_male_8 weeks |
| GSM1835359 |
Col2a1Tsc1KO_knee joint cartilage_male_8 weeks |
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| Relations |
| BioProject |
PRJNA291366 |
