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| Status |
Public on Oct 28, 2015 |
| Title |
Genome-wide analysis of TRA (tissue restricted antigen)-specific co-expression groups in mouse medullary thymic epithelial cells (mTECs) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of gene co-expression patterns in TRA-specific medullary thymic epithelial cell (mTEC) subsets. The whole genome gene signatures of purified mTEC subsets respectively positive for the TRAs Gp2, Pdpn, Cea1, Gad1, Ins2, Tspan8 were compared to their corresponding TRA-negative mTEC subset control. Results provide the enriched and depleted gene expressions in the different subsets.
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| |
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| Overall design |
Total RNA obtained from FACS isolated mTECs positive for the respective TRAs were compared to their TRA-negative mTEC subsets using specific antibodies (Pdpn, Gp2, Cea1, Tspan8) or reporter mice (Gad1, Ins2).
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| |
|
| Contributor(s) |
Rattay K, Kyewski B |
| Citation(s) |
26481130 |
| |
| Submission date |
Jun 01, 2015 |
| Last update date |
Nov 24, 2017 |
| Contact name |
Kristin Rattay |
| E-mail(s) |
[email protected]
|
| Organization name |
German Cancer Research Center
|
| Department |
D090
|
| Lab |
Developmental Immunology
|
| Street address |
Im Neuenheimer Feld 280
|
| City |
Heidelberg |
| ZIP/Postal code |
69120 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL17543 |
Illumina MouseWG-6 v2.0 R2 expression beadchip |
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| Samples (35)
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| Relations |
| BioProject |
PRJNA285490 |
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