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| Status |
Public on Feb 28, 2015 |
| Title |
Autoimmune peptide antigen reactivity in BXD2 mice with spontaneous systemic autoimmune disease |
| Platform organisms |
Klebsiella pneumoniae; Proteus mirabilis; Mycobacterium tuberculosis; Homo sapiens; Human alphaherpesvirus 2; human gammaherpesvirus 4; Caprine arthritis encephalitis virus; Human endogenous retrovirus K; Torque teno virus |
| Sample organism |
Mus musculus |
| Experiment type |
Protein profiling by protein array
|
| Summary |
The aim of the study was to determine autoimmune BXD2 mouse sera reactivity to linear peptide epitopes from the Immune Epitope Database. Pooled sera from six 8-10 month old BXD2 mice was diluted at 1:1000 and incubated on a PEPperPRINT peptide microarray platform printed with peptide autoantigens.
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| Overall design |
In this study, pooled sera from six 8-10 month old BXD2 mice was profiled for anti-mouse IgG (H+L) analysis of autoantibody reactivity to peptide auto-epitopes printed in duplicate on a PepperPrint Chip.
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| Contributor(s) |
Hamilton JA, Mountz JD, Hsu H |
| Citation(s) |
25888644 |
| |
| Submission date |
Jan 26, 2015 |
| Last update date |
May 30, 2015 |
| Contact name |
Jennie Hamilton |
| Organization name |
University of Alabama Birmingham
|
| Department |
Department of Medicine, Division of Clinical Immunology and Rheumatology
|
| Street address |
1825 University Blvd.
|
| City |
Birmingham |
| State/province |
AL |
| ZIP/Postal code |
35294 |
| Country |
USA |
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| Platforms (1) |
| GPL19700 |
PEPperCHIP Autoimmunity Microarray |
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| Samples (1) |
| GSM1591569 |
pooled sera from six 8-10 month old BXD2 mice |
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| This SubSeries is part of SuperSeries: |
| GSE65290 |
General Approach for Tetramer Based Identification of Autoantigen Reactive B Cells: Characterization of La and snRNP Reactive B Cells in Autoimmune BXD2 Mice |
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| Relations |
| BioProject |
PRJNA273612 |
