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| Status |
Public on Oct 17, 2014 |
| Title |
FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Single-color gene expression profiles from 3 neuroblastoma cell lines were generated using 44K oligonucleotide microarrays. To gain insights into the molecular processes occurring upon FOXP1 re-expression, we performed series of time-resolved gene expression measurements in FOXP1 and GFP transgenic neuroblastoma cell lines.
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| Overall design |
Single-color gene expression profiles from 3 neuroblastoma cell lines were generated using 44K oligonucleotide microarrays. Total RNA of FOXP1- and GFP-expressing IMR-32, CHP-212 and SK-N-BE(2) cells was isolated at 0, 12, 24 and 72 h using Trizol. To determine global differences in the expression profiles of FOXP1- and GFP-induced IMR-32, CHP-212 and SK-N-BE(2) cells, mean expression levels of each gene between FOXP1-induced and control (GFP) cells were compared.
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| Contributor(s) |
Ackermann S, Fischer M, Roels F |
| Citation(s) |
25406647 |
| |
| Submission date |
Oct 16, 2014 |
| Last update date |
Jan 16, 2015 |
| Contact name |
Sandra Ackermann |
| E-mail(s) |
[email protected]
|
| Organization name |
University Hospital of Cologne
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| Department |
Pediatric Oncology and Hematology
|
| Street address |
Kerpener Str. 62, Geb. 26, UG
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| City |
Cologne |
| ZIP/Postal code |
50924 |
| Country |
Germany |
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| Platforms (1) |
| GPL16876 |
Agilent-020382 Human Custom Microarray 44k (Feature Number version) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA264062 |
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