|
| Status |
Public on Oct 01, 2015 |
| Title |
mRNA sequencing of Trim71 conditional ("WT") and Trim71 KO mES cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report that Trim71 mutation does not lead to significant changes within the core regulatory network of mES cells, however, there is an upregulation of specific genes involved in neural differentiation. We thus conclude that Trim71 KO mES cells are poised for differentiation.
|
| |
|
| Overall design |
Analysis of changes in the expression of mRNAs in two different genotypes
|
| |
|
| Contributor(s) |
Mitschka S, Goller T, Schneider K, Kolanus W, Egert A, Schorle H, Ulas T, Günther P, Bassler K, Xue J, Schultze JL |
| Citation(s) |
26057209 |
| |
| Submission date |
Oct 16, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Joachim Schultze |
| E-mail(s) |
[email protected]
|
| Organization name |
LIMES (Life and Medical Sciences Center Genomics and Immunoregulation)
|
| Department |
Genomics and Immunoregulation
|
| Street address |
Carl-Troll-Strasse 31
|
| City |
Bonn |
| State/province |
NRW |
| ZIP/Postal code |
53115 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA264013 |
| SRA |
SRP048967 |
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