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| Status |
Public on May 01, 2015 |
| Title |
Treatment of C3H/HeJ grafted mice with baricitinib [prevention] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The C3H/HeJ grafted model of alopecia areata was used to determine the efficacy of systemic baricitinib at preventing alopecia or treating established disease.
The efficacy of topical baricitinib at treating established alopecia in the C3H/HeJ grafted model was also assessed. Microarrays were performed on skin RNA at week 0 and week 12 after starting treatment in all models.
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| Overall design |
Baricitinib was administered in systemic form at the time of grafting. Skin samples were taken after 12 weeks.
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| Contributor(s) |
Jabbari A, Cerise JE, Christiano AM |
| Citation(s) |
26137574 |
| |
| Submission date |
Sep 18, 2014 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Ali Jabbari |
| Organization name |
University of Iowa
|
| Street address |
200 Hawkins Dr, 40025 PFP
|
| City |
Iowa City |
| State/province |
IA |
| ZIP/Postal code |
52242 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE61555 |
Treatment of C3H/HeJ grafted mice with baricitinib |
|
| Relations |
| BioProject |
PRJNA261448 |
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