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| Status |
Public on Dec 31, 2014 |
| Title |
Expression data from MDA-MB-231 cells over-expressing RRP1B and MDA-MB-231 control cells with endogenous RRP1B levels |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
RRP1B is a breast cancer metastasis suppressor that interacts with various regulators of gene transcription
We examined the changes in gene expression caused by the stable over-expression of RRP1B using lentiviral transduction in the human breast cancer cell line MDA-MB-231.
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| Overall design |
10 total samples were analyzed. We generated the following pairwise comparisons using Partek: WT<Ctrl;. Genes with a Benjamini-Hochberg corrected p-value <0.05 and a fold-change ≥abs(2.5) were selected.
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| Contributor(s) |
Lee M, Dworkin AM, Trivedi NS |
| Citation(s) |
25092915 |
| |
| Submission date |
Jan 10, 2014 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Nigel P.S. Crawford |
| E-mail(s) |
[email protected]
|
| Organization name |
Human Genome Research Institute
|
| Street address |
50 South Drive, Room 5154
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (10)
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| GSM1304748 |
MDA-MB-231 RRP1B over-expressing clone #5 |
| GSM1304749 |
MDA-MB-231 RRP1B over-expressing clone #7 |
| GSM1304750 |
MDA-MB-231 RRP1B over-expressing clone #8 |
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| Relations |
| BioProject |
PRJNA234272 |
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