|
| Status |
Public on Sep 04, 2013 |
| Title |
Histone Deacetylase Inhibition Promotes Osteoblast Maturation by Altering the Histone 4 (H4) Epigenome (BeadChip) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Suberoylanilidehydroxamic acid (SAHA) significantly increased the expression levels of 127 transcripts and suppressed expression of 130 genes by more than 2-fold within 3 standard deviations of the mean in differentiating MC3T3 sc4 osteoblasts
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| |
|
| Overall design |
Total RNA was obtained from differentiating MC3T3 sc4 cells treated with SAHA or vehicle (DMSO).
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| |
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| Contributor(s) |
Dudakovic A, Evans JM, Li Y, Middha S, McGee-Lawrence ME, van Wijnen AJ, Westendorf JJ |
| Citation(s) |
23940046 |
| |
| Submission date |
Sep 03, 2013 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Jennifer Westendorf |
| Organization name |
Mayo Clinic
|
| Street address |
200 1st St SW
|
| City |
Rochester |
| ZIP/Postal code |
55901 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
|
| Samples (12)
|
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| This SubSeries is part of SuperSeries: |
| GSE50552 |
Histone Deacetylase Inhibition Promotes Osteoblast Maturation by Altering the Histone 4 (H4) Epigenome |
|
| Relations |
| BioProject |
PRJNA217928 |
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