|
| Status |
Public on Jul 16, 2003 |
| Title |
Alveoli septation inhibition and protection |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
It has been shown that dexamethasone (Dex) impairs the normal lung septation that occurs in the early postnatal period. Treatment with retinoic acid (ATRA) abrogates the effects of Dex. To understand the molecular basis for the Dex indiced inhibition of the formation of the alveoli and the ability of ATRA to prevent the inhibition of septation, gene expression was analyzed in 4-day old mice treated with diluent (control), Dex-treated and ATRA+Dex-treated.
Keywords: other
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| Contributor(s) |
Clerch L |
| Citation(s) |
14607780 |
| |
| Submission date |
Jun 27, 2003 |
| Last update date |
Oct 01, 2019 |
| Contact name |
Eric P Hoffman |
| E-mail(s) |
[email protected]
|
| Organization name |
Binghamton University - SUNY
|
| Department |
Pharmaceutical Sciences
|
| Street address |
PO Box 6000
|
| City |
Binghamton |
| State/province |
NY |
| ZIP/Postal code |
13902 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL81 |
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA85175 |
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