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| Status |
Public on Oct 17, 2012 |
| Title |
Deletion effect of HstD in gene expression |
| Platform organism |
Aspergillus oryzae RIB40 |
| Sample organism |
Aspergillus oryzae |
| Experiment type |
Expression profiling by array
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| Summary |
In eukaryotic cells , histone deactylase plays key roles in the diverse process such as genomic stabillity, differenciation, and metabolism. These enzymes also conserved in filamentous fungi, and their functios has been started to understand some fungal biological process such as development, stress responce, and secondary metabolism. We found deletion of HstD homolog of yeast Hst4, affected development, secondary metabolism in aspergillyus oryzae. To acess the global effect of gene expression by HstD deletion, we performed microarray analysis, and results showed metabolite related gene was mainly alterd in DHstD. This result sugested the HstD will concerned golobal regulation of secondary metabolism in filmatous fungi.
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| Overall design |
Control strain was used as refrence of dHstD strain. Two indipendent strain was used to this experiment.
biological replicate: Control-1, Control-2
biological replicate: dHstD-1, dHstD-2
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| Contributor(s) |
Iwashita K, Kawauchi M |
| Citation(s) |
23729383 |
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| Submission date |
Oct 16, 2012 |
| Last update date |
Sep 03, 2013 |
| Contact name |
Kazuhiro Iwashita |
| E-mail(s) |
[email protected]
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| Phone |
+81-82-420-0824
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| Fax |
+81-82-420-0808
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| Organization name |
National Research Institute of Brewing
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| Street address |
3-7-1, Kagamiyama
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| City |
Higashihiroshima |
| State/province |
Hiroshima |
| ZIP/Postal code |
739-0046 |
| Country |
Japan |
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| Platforms (1) |
| GPL16184 |
[Aoryzaea520360F] Affymetrix Aspergillus oryzae DNAchip |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA177685 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE41612_RAW.tar |
20.9 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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