NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE276027 Query DataSets for GSE276027
Status Public on Oct 25, 2024
Title Pathogenic mtDNA mutations inhibit melanoma metastasis
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We report the transcriptome profiles of A375 melanoma tumors containing distinct mtDNA mutations. This study was performed using subcutaneous tumors implanted into NSG mice, and identifies transcriptomice changes in response to pathogenic mtDNA mutations.
 
Overall design A375 cells containing various mtDNA mutations were implanted into NSG mice to create subcutaneous tumors. Subcutaneous tumors were harvested at 20-25mm in diameter for RNAseq analysis.
 
Contributor(s) Mishra P, Tasdogan A, Shelton S
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Aug 29, 2024
Last update date Oct 25, 2024
Contact name Prashant Mishra
E-mail(s) [email protected]
Organization name University of Texas Southwestern Medical Center
Street address 5323 Harry Hines Blvd
City Dallas
State/province TX
ZIP/Postal code 75390
Country USA
 
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (13)
GSM8489717 A375, WT mtDNA, replicate (mouse) 1
GSM8489718 A375, WT mtDNA, replicate (mouse) 2
GSM8489719 A375, WT mtDNA, replicate (mouse) 3
Relations
BioProject PRJNA1154298

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE276027_counts.xlsx 3.5 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap